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Journal Abstract Search

228 related items for PubMed ID: 12699388

  • 1. Synthesis and biological evaluation of N-heterocyclic indolyl glyoxylamides as orally active anticancer agents.
    Li WT, Hwang DR, Chen CP, Shen CW, Huang CL, Chen TW, Lin CH, Chang YL, Chang YY, Lo YK, Tseng HY, Lin CC, Song JS, Chen HC, Chen SJ, Wu SH, Chen CT.
    J Med Chem; 2003 Apr 24; 46(9):1706-15. PubMed ID: 12699388
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological activities of 2-amino-1-arylidenamino imidazoles as orally active anticancer agents.
    Li WT, Hwang DR, Song JS, Chen CP, Chuu JJ, Hu CB, Lin HL, Huang CL, Huang CY, Tseng HY, Lin CC, Chen TW, Lin CH, Wang HS, Shen CC, Chang CM, Chao YS, Chen CT.
    J Med Chem; 2010 Mar 25; 53(6):2409-17. PubMed ID: 20170097
    [Abstract] [Full Text] [Related]

  • 3. Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
    Hoch U, Lynch J, Sato Y, Kashimoto S, Kajikawa F, Furutani Y, Silverman JA.
    Cancer Chemother Pharmacol; 2009 Jun 25; 64(1):53-65. PubMed ID: 18931998
    [Abstract] [Full Text] [Related]

  • 4. BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities.
    Hu CB, Chen CP, Yeh TK, Song JS, Chang CY, Chuu JJ, Tung FF, Ho PY, Chen TW, Lin CH, Wang MH, Chang KY, Huang CL, Lin HL, Li WT, Hwang DR, Chern JH, Hwang LL, Chang JY, Chao YS, Chen CT.
    Cancer Sci; 2011 Jan 25; 102(1):182-91. PubMed ID: 21040217
    [Abstract] [Full Text] [Related]

  • 5. An efficient synthesis and biological study of novel indolyl-1,3,4-oxadiazoles as potent anticancer agents.
    Kumar D, Sundaree S, Johnson EO, Shah K.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4492-4. PubMed ID: 19559607
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and anticancer activity of 5-(3-indolyl)-1,3,4-thiadiazoles.
    Kumar D, Maruthi Kumar N, Chang KH, Shah K.
    Eur J Med Chem; 2010 Oct 01; 45(10):4664-8. PubMed ID: 20692741
    [Abstract] [Full Text] [Related]

  • 7. Antitumor activity of new substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and 3-(5-imidazo[2,1-b]thiadiazolylmethylene)-2-indolinones: selectivity against colon tumor cells and effect on cell cycle-related events.
    Andreani A, Burnelli S, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Calonghi N, Cappadone C, Voltattorni M, Zini M, Stefanelli C, Masotti L, Shoemaker RH.
    J Med Chem; 2008 Dec 11; 51(23):7508-13. PubMed ID: 19006285
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation of 1-(4'-Indolyl and 6'-Quinolinyl) indoles as a new class of potent anticancer agents.
    Lai MJ, Chang JY, Lee HY, Kuo CC, Lin MH, Hsieh HP, Chang CY, Wu JS, Wu SY, Shey KS, Liou JP.
    Eur J Med Chem; 2011 Sep 11; 46(9):3623-9. PubMed ID: 21641700
    [Abstract] [Full Text] [Related]

  • 9. 8,11-dihydroxy-6-[(aminoalkyl)amino]-7H-benzo[e]perimidin-7-ones with activity in multidrug-resistant cell lines: synthesis and antitumor evaluation.
    Stefańska B, Dzieduszycka M, Bontemps-Gracz MM, Borowski E, Martelli S, Supino R, Pratesi G, De Cesare M, Zunino F, Kuśnierczyk H, Radzikowski C.
    J Med Chem; 1999 Sep 09; 42(18):3494-501. PubMed ID: 10479282
    [Abstract] [Full Text] [Related]

  • 10. A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties.
    Kupchinsky S, Centioni S, Howard T, Trzupek J, Roller S, Carnahan V, Townes H, Purnell B, Price C, Handl H, Summerville K, Johnson K, Toth J, Hudson S, Kiakos K, Hartley JA, Lee M.
    Bioorg Med Chem; 2004 Dec 01; 12(23):6221-36. PubMed ID: 15519165
    [Abstract] [Full Text] [Related]

  • 11. Antitumor agents 253. Design, synthesis, and antitumor evaluation of novel 9-substituted phenanthrene-based tylophorine derivatives as potential anticancer agents.
    Wei L, Shi Q, Bastow KF, Brossi A, Morris-Natschke SL, Nakagawa-Goto K, Wu TS, Pan SL, Teng CM, Lee KH.
    J Med Chem; 2007 Jul 26; 50(15):3674-80. PubMed ID: 17585747
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridines.
    Deady LW, Rodemann T, Zhuang L, Baguley BC, Denny WA.
    J Med Chem; 2003 Mar 13; 46(6):1049-54. PubMed ID: 12620081
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and in vitro evaluation of the anticancer activity of novel fluorinated thiazolo[4, 5-d]pyrimidines.
    Fahmy HT, Rostom SA, Saudi MN, Zjawiony JK, Robins DJ.
    Arch Pharm (Weinheim); 2003 Jul 13; 336(4-5):216-25. PubMed ID: 12916055
    [Abstract] [Full Text] [Related]

  • 14. Effect of stealthy liposomal topotecan plus amlodipine on the multidrug-resistant leukaemia cells in vitro and xenograft in mice.
    Li X, Lu WL, Liang GW, Ruan GR, Hong HY, Long C, Zhang YT, Liu Y, Wang JC, Zhang X, Zhang Q.
    Eur J Clin Invest; 2006 Jun 13; 36(6):409-18. PubMed ID: 16684125
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and evaluation of novel 7-azaindazolyl-indolyl-maleimide derivatives as antitumor agents and protein kinase C inhibitors.
    Ye Q, Cao J, Zhou X, Lv D, He Q, Yang B, Hu Y.
    Bioorg Med Chem; 2009 Jul 01; 17(13):4763-72. PubMed ID: 19447039
    [Abstract] [Full Text] [Related]

  • 16. Novel multidrug resistance reversal agents.
    Berger D, Citarella R, Dutia M, Greenberger L, Hallett W, Paul R, Powell D.
    J Med Chem; 1999 Jun 17; 42(12):2145-61. PubMed ID: 10377220
    [Abstract] [Full Text] [Related]

  • 17. A novel class of in vivo active anticancer agents: achiral seco-amino- and seco-hydroxycyclopropylbenz[e]indolone (seco-CBI) analogues of the duocarmycins and CC-1065.
    Sato A, McNulty L, Cox K, Kim S, Scott A, Daniell K, Summerville K, Price C, Hudson S, Kiakos K, Hartley JA, Asao T, Lee M.
    J Med Chem; 2005 Jun 02; 48(11):3903-18. PubMed ID: 15916443
    [Abstract] [Full Text] [Related]

  • 18. Novel antitumor agent family of 1H-benzo[c,d]indol-2-one with flexible basic side chains: synthesis and biological evaluation.
    Yin H, Xu Y, Qian X.
    Bioorg Med Chem; 2007 Feb 01; 15(3):1356-62. PubMed ID: 17129733
    [Abstract] [Full Text] [Related]

  • 19. 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors.
    Beckers T, Reissmann T, Schmidt M, Burger AM, Fiebig HH, Vanhoefer U, Pongratz H, Hufsky H, Hockemeyer J, Frieser M, Mahboobi S.
    Cancer Res; 2002 Jun 01; 62(11):3113-9. PubMed ID: 12036922
    [Abstract] [Full Text] [Related]

  • 20. One pot synthesis of thiazolodihydropyrimidinones and evaluation of their anticancer activity.
    Holla BS, Rao BS, Sarojini BK, Akberali PM.
    Eur J Med Chem; 2004 Sep 01; 39(9):777-83. PubMed ID: 15337290
    [Abstract] [Full Text] [Related]

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