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157 related items for PubMed ID: 12700301

  • 1. Attenuated nuclear shrinkage in neurones with nuclear inclusions of SCA1 brains.
    Nagaoka U, Uchihara T, Iwabuchi K, Konno H, Tobita M, Funata N, Yagishita S, Kato T.
    J Neurol Neurosurg Psychiatry; 2003 May; 74(5):597-601. PubMed ID: 12700301
    [Abstract] [Full Text] [Related]

  • 2. Attenuated nuclear shrinkage in neurons with nuclear aggregates--a morphometric study on pontine neurons of Machado-Joseph disease brains.
    Uchihara T, Iwabuchi K, Funata N, Yagishita S.
    Exp Neurol; 2002 Nov; 178(1):124-8. PubMed ID: 12460614
    [Abstract] [Full Text] [Related]

  • 3. Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.
    Chen HK, Fernandez-Funez P, Acevedo SF, Lam YC, Kaytor MD, Fernandez MH, Aitken A, Skoulakis EM, Orr HT, Botas J, Zoghbi HY.
    Cell; 2003 May 16; 113(4):457-68. PubMed ID: 12757707
    [Abstract] [Full Text] [Related]

  • 4. Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice.
    Emamian ES, Kaytor MD, Duvick LA, Zu T, Tousey SK, Zoghbi HY, Clark HB, Orr HT.
    Neuron; 2003 May 08; 38(3):375-87. PubMed ID: 12741986
    [Abstract] [Full Text] [Related]

  • 5. Progress in pathogenesis studies of spinocerebellar ataxia type 1.
    Cummings CJ, Orr HT, Zoghbi HY.
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun 29; 354(1386):1079-81. PubMed ID: 10434309
    [Abstract] [Full Text] [Related]

  • 6. Non-expanded polyglutamine proteins in intranuclear inclusions of hereditary ataxias--triple-labeling immunofluorescence study.
    Uchihara T, Fujigasaki H, Koyano S, Nakamura A, Yagishita S, Iwabuchi K.
    Acta Neuropathol; 2001 Aug 29; 102(2):149-52. PubMed ID: 11563629
    [Abstract] [Full Text] [Related]

  • 7. Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.
    Cummings CJ, Reinstein E, Sun Y, Antalffy B, Jiang Y, Ciechanover A, Orr HT, Beaudet AL, Zoghbi HY.
    Neuron; 1999 Dec 29; 24(4):879-92. PubMed ID: 10624951
    [Abstract] [Full Text] [Related]

  • 8. Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death.
    Okazawa H, Rich T, Chang A, Lin X, Waragai M, Kajikawa M, Enokido Y, Komuro A, Kato S, Shibata M, Hatanaka H, Mouradian MM, Sudol M, Kanazawa I.
    Neuron; 2002 May 30; 34(5):701-13. PubMed ID: 12062018
    [Abstract] [Full Text] [Related]

  • 9. USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.
    Hong S, Kim SJ, Ka S, Choi I, Kang S.
    Mol Cell Neurosci; 2002 Jun 30; 20(2):298-306. PubMed ID: 12093161
    [Abstract] [Full Text] [Related]

  • 10. Reduction of Purkinje cell pathology in SCA1 transgenic mice by p53 deletion.
    Shahbazian MD, Orr HT, Zoghbi HY.
    Neurobiol Dis; 2001 Dec 30; 8(6):974-81. PubMed ID: 11741393
    [Abstract] [Full Text] [Related]

  • 11. Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.
    Brusco A, Gellera C, Cagnoli C, Saluto A, Castucci A, Michielotto C, Fetoni V, Mariotti C, Migone N, Di Donato S, Taroni F.
    Arch Neurol; 2004 May 30; 61(5):727-33. PubMed ID: 15148151
    [Abstract] [Full Text] [Related]

  • 12. 14-3-3 proteins and spinocerebellar ataxia type 1: from molecular interaction to human neuropathology.
    Umahara T, Uchihara T.
    Cerebellum; 2010 Jun 30; 9(2):183-9. PubMed ID: 20155408
    [Abstract] [Full Text] [Related]

  • 13. Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice.
    Zu T, Duvick LA, Kaytor MD, Berlinger MS, Zoghbi HY, Clark HB, Orr HT.
    J Neurosci; 2004 Oct 06; 24(40):8853-61. PubMed ID: 15470152
    [Abstract] [Full Text] [Related]

  • 14. Neuropathological staging of spinocerebellar ataxia type 2 by semiquantitative 1C2-positive neuron typing. Nuclear translocation of cytoplasmic 1C2 underlies disease progression of spinocerebellar ataxia type 2.
    Koyano S, Yagishita S, Kuroiwa Y, Tanaka F, Uchihara T.
    Brain Pathol; 2014 Nov 06; 24(6):599-606. PubMed ID: 24674145
    [Abstract] [Full Text] [Related]

  • 15. Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions.
    Holmberg M, Duyckaerts C, Dürr A, Cancel G, Gourfinkel-An I, Damier P, Faucheux B, Trottier Y, Hirsch EC, Agid Y, Brice A.
    Hum Mol Genet; 1998 May 06; 7(5):913-8. PubMed ID: 9536097
    [Abstract] [Full Text] [Related]

  • 16. Dopamine D2 receptor signaling modulates mutant ataxin-1 S776 phosphorylation and aggregation.
    Hearst SM, Lopez ME, Shao Q, Liu Y, Vig PJ.
    J Neurochem; 2010 Aug 06; 114(3):706-16. PubMed ID: 20477910
    [Abstract] [Full Text] [Related]

  • 17. Glial S100B protein modulates mutant ataxin-1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy.
    Vig PJ, Hearst S, Shao Q, Lopez ME, Murphy HA, Safaya E.
    Cerebellum; 2011 Jun 06; 10(2):254-66. PubMed ID: 21384195
    [Abstract] [Full Text] [Related]

  • 18. Intranuclear immunolocalization of 14-3-3 protein isoforms in brains with spinocerebellar ataxia type 1.
    Umahara T, Uchihara T, Yagishita S, Nakamura A, Tsuchiya K, Iwamoto T.
    Neurosci Lett; 2007 Mar 06; 414(2):130-5. PubMed ID: 17224237
    [Abstract] [Full Text] [Related]

  • 19. Neuronal intranuclear inclusions in spinocerebellar ataxia type 2: triple-labeling immunofluorescent study.
    Koyano S, Uchihara T, Fujigasaki H, Nakamura A, Yagishita S, Iwabuchi K.
    Neurosci Lett; 1999 Oct 01; 273(2):117-20. PubMed ID: 10505630
    [Abstract] [Full Text] [Related]

  • 20. Spinocerebellar ataxia type 1--modeling the pathogenesis of a polyglutamine neurodegenerative disorder in transgenic mice.
    Clark HB, Orr HT.
    J Neuropathol Exp Neurol; 2000 Apr 01; 59(4):265-70. PubMed ID: 10759181
    [Abstract] [Full Text] [Related]

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