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203 related items for PubMed ID: 12700394

  • 1. Expression and activity of cytochromes P450 2E1, 2A, and 2B in the mouse ovary: the effect of 4-vinylcyclohexene and its diepoxide metabolite.
    Cannady EA, Dyer CA, Christian PJ, Sipes IG, Hoyer PB.
    Toxicol Sci; 2003 Jun; 73(2):423-30. PubMed ID: 12700394
    [Abstract] [Full Text] [Related]

  • 2. Enhanced expression of bax in small preantral follicles during 4-vinylcyclohexene diepoxide-induced ovotoxicity in the rat.
    Springer LN, Tilly JL, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 1996 Aug; 139(2):402-10. PubMed ID: 8806858
    [Abstract] [Full Text] [Related]

  • 3. Induction of cytochrome P-450 enzymes after repeated exposure to 4-vinylcyclohexene in B6C3F1 mice.
    Doerr-Stevens JK, Liu J, Stevens GJ, Kraner JC, Fontaine SM, Halpert JR, Sipes IG.
    Drug Metab Dispos; 1999 Feb; 27(2):281-7. PubMed ID: 9929517
    [Abstract] [Full Text] [Related]

  • 4. Expression and activity of microsomal epoxide hydrolase in follicles isolated from mouse ovaries.
    Cannady EA, Dyer CA, Christian PJ, Sipes IG, Hoyer PB.
    Toxicol Sci; 2002 Jul; 68(1):24-31. PubMed ID: 12075107
    [Abstract] [Full Text] [Related]

  • 5. Involvement of apoptosis in 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats.
    Springer LN, McAsey ME, Flaws JA, Tilly JL, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 1996 Aug; 139(2):394-401. PubMed ID: 8806857
    [Abstract] [Full Text] [Related]

  • 6. Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss.
    Thompson KE, Bourguet SM, Christian PJ, Benedict JC, Sipes IG, Flaws JA, Hoyer PB.
    Toxicol Appl Pharmacol; 2005 Mar 01; 203(2):114-23. PubMed ID: 15710172
    [Abstract] [Full Text] [Related]

  • 7. Ovotoxicity in female Fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index.
    Borman SM, Christian PJ, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 2000 Sep 15; 167(3):191-8. PubMed ID: 10986010
    [Abstract] [Full Text] [Related]

  • 8. Characterization of a rat in vitro ovarian culture system to study the ovarian toxicant 4-vinylcyclohexene diepoxide.
    Devine PJ, Sipes IG, Skinner MK, Hoyer PB.
    Toxicol Appl Pharmacol; 2002 Oct 15; 184(2):107-15. PubMed ID: 12408955
    [Abstract] [Full Text] [Related]

  • 9. A single dose of the ovotoxicant 4-vinylcyclohexene diepoxide is protective in rat primary ovarian follicles.
    Borman SM, VanDePol BJ, Kao S, Thompson KE, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 1999 Aug 01; 158(3):244-52. PubMed ID: 10438657
    [Abstract] [Full Text] [Related]

  • 10. Stereochemical aspects of vinylcyclohexene bioactivation in rodent hepatic microsomes and purified human cytochrome P450 enzyme systems.
    Fontaine SM, Mash EA, Hoyer PB, Sipes IG.
    Drug Metab Dispos; 2001 Feb 01; 29(2):179-84. PubMed ID: 11159809
    [Abstract] [Full Text] [Related]

  • 11. Role of induction of specific hepatic cytochrome P450 isoforms in epoxidation of 4-vinylcyclohexene.
    Fontaine SM, Hoyer PB, Halpert JR, Sipes IG.
    Drug Metab Dispos; 2001 Sep 01; 29(9):1236-42. PubMed ID: 11502734
    [Abstract] [Full Text] [Related]

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  • 13. Involvement of CYP 2E1 enzyme in ovotoxicity caused by 4-vinylcyclohexene and its metabolites.
    Rajapaksa KS, Cannady EA, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 2007 Jun 01; 221(2):215-21. PubMed ID: 17462685
    [Abstract] [Full Text] [Related]

  • 14. Initiation of delayed ovotoxicity by in vitro and in vivo exposures of rat ovaries to 4-vinylcyclohexene diepoxide.
    Devine PJ, Sipes IG, Hoyer PB.
    Reprod Toxicol; 2004 Nov 01; 19(1):71-7. PubMed ID: 15336714
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  • 16. Expression and redistribution of cellular Bad, Bax, and Bcl-X(L) protein is associated with VCD-induced ovotoxicity in rats.
    Hu X, Christian P, Sipes IG, Hoyer PB.
    Biol Reprod; 2001 Nov 01; 65(5):1489-95. PubMed ID: 11673266
    [Abstract] [Full Text] [Related]

  • 17. Evaluation of hepatic cytochrome P4502E1 in the species-dependent bioactivation of 4-vinylcyclohexene.
    Fontaine SM, Hoyer PB, Sipes IG.
    Life Sci; 2001 Jul 13; 69(8):923-34. PubMed ID: 11488405
    [Abstract] [Full Text] [Related]

  • 18. In vitro metabolism of 4-vinylcyclohexene in rat and mouse liver, lung, and ovary.
    Keller DA, Carpenter SC, Cagen SZ, Reitman FA.
    Toxicol Appl Pharmacol; 1997 May 13; 144(1):36-44. PubMed ID: 9169067
    [Abstract] [Full Text] [Related]

  • 19. Follicular mechanisms associated with 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats.
    Springer LN, Flaws JA, Sipes IG, Hoyer PB.
    Reprod Toxicol; 1996 May 13; 10(2):137-43. PubMed ID: 8919611
    [Abstract] [Full Text] [Related]

  • 20. Development of an animal model for ovotoxicity using 4-vinylcyclohexene: a case study.
    Hoyer PB, Sipes IG.
    Birth Defects Res B Dev Reprod Toxicol; 2007 Apr 13; 80(2):113-25. PubMed ID: 17342769
    [Abstract] [Full Text] [Related]

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