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174 related items for PubMed ID: 12706337

  • 1. Substrate inhibition of Lactococcus lactis cytidine 5'-triphosphate synthase by ammonium chloride is enhanced by salt-dependent tetramer dissociation.
    Willemoës M, Larsen S.
    Arch Biochem Biophys; 2003 May 01; 413(1):17-22. PubMed ID: 12706337
    [Abstract] [Full Text] [Related]

  • 2. Competition between ammonia derived from internal glutamine hydrolysis and hydroxylamine present in the solution for incorporation into UTP as catalysed by Lactococcus lactis CTP synthase.
    Willemoës M.
    Arch Biochem Biophys; 2004 Apr 01; 424(1):105-11. PubMed ID: 15019842
    [Abstract] [Full Text] [Related]

  • 3. Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis. The role of the allosteric activator GTP incoupling between glutamine hydrolysis and CTP synthesis.
    Willemoës M, Sigurskjold BW.
    Eur J Biochem; 2002 Oct 01; 269(19):4772-9. PubMed ID: 12354108
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of E. coli CTP synthase by the "positive" allosteric effector GTP.
    MacDonnell JE, Lunn FA, Bearne SL.
    Biochim Biophys Acta; 2004 Jun 01; 1699(1-2):213-20. PubMed ID: 15158730
    [Abstract] [Full Text] [Related]

  • 5. Thr-431 and Arg-433 are part of a conserved sequence motif of the glutamine amidotransferase domain of CTP synthases and are involved in GTP activation of the Lactococcus lactis enzyme.
    Willemoës M.
    J Biol Chem; 2003 Mar 14; 278(11):9407-11. PubMed ID: 12522217
    [Abstract] [Full Text] [Related]

  • 6. Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax.
    Lunn FA, MacDonnell JE, Bearne SL.
    J Biol Chem; 2008 Jan 25; 283(4):2010-20. PubMed ID: 18003612
    [Abstract] [Full Text] [Related]

  • 7. Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus.
    Lauritsen I, Willemoës M, Jensen KF, Johansson E, Harris P.
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2011 Feb 01; 67(Pt 2):201-8. PubMed ID: 21301086
    [Abstract] [Full Text] [Related]

  • 8. Cloning and verification of the Lactococcus lactis pyrG gene and characterization of the gene product, CTP synthase.
    Wadskov-Hansen SL, Willemoës M, Martinussen J, Hammer K, Neuhard J, Larsen S.
    J Biol Chem; 2001 Oct 12; 276(41):38002-9. PubMed ID: 11500486
    [Abstract] [Full Text] [Related]

  • 9. Limited proteolysis of Escherichia coli cytidine 5'-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis.
    Simard D, Hewitt KA, Lunn F, Iyengar A, Bearne SL.
    Eur J Biochem; 2003 May 12; 270(10):2195-206. PubMed ID: 12752439
    [Abstract] [Full Text] [Related]

  • 10. Alternative substrates for wild-type and L109A E. coli CTP synthases: kinetic evidence for a constricted ammonia tunnel.
    Lunn FA, Bearne SL.
    Eur J Biochem; 2004 Nov 12; 271(21):4204-12. PubMed ID: 15511226
    [Abstract] [Full Text] [Related]

  • 11. The role of lysine residues 297 and 306 in nucleoside triphosphate regulation of E. coli CTP synthase: inactivation by 2',3'-dialdehyde ATP and mutational analyses.
    MacLeod TJ, Lunn FA, Bearne SL.
    Biochim Biophys Acta; 2006 Feb 12; 1764(2):199-210. PubMed ID: 16427816
    [Abstract] [Full Text] [Related]

  • 12. CTP synthetase from Escherichia coli: an improved purification procedure and characterization of hysteretic and enzyme concentration effects on kinetic properties.
    Anderson PM.
    Biochemistry; 1983 Jun 21; 22(13):3285-92. PubMed ID: 6349684
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of Escherichia coli CTP synthase by glutamate gamma-semialdehyde and the role of the allosteric effector GTP in glutamine hydrolysis.
    Bearne SL, Hekmat O, Macdonnell JE.
    Biochem J; 2001 May 15; 356(Pt 1):223-32. PubMed ID: 11336655
    [Abstract] [Full Text] [Related]

  • 14. Mutational analysis of conserved glycine residues 142, 143 and 146 reveals Gly(142) is critical for tetramerization of CTP synthase from Escherichia coli.
    Lunn FA, Macleod TJ, Bearne SL.
    Biochem J; 2008 May 15; 412(1):113-21. PubMed ID: 18260824
    [Abstract] [Full Text] [Related]

  • 15. Substrate specificity of CTP synthetase from Escherichia coli.
    Scheit KH, Linke HJ.
    Eur J Biochem; 1982 Aug 15; 126(1):57-60. PubMed ID: 6751817
    [Abstract] [Full Text] [Related]

  • 16. "Pinching" the ammonia tunnel of CTP synthase unveils coordinated catalytic and allosteric-dependent control of ammonia passage.
    McCluskey GD, Bearne SL.
    Biochim Biophys Acta Gen Subj; 2018 Dec 15; 1862(12):2714-2727. PubMed ID: 30251661
    [Abstract] [Full Text] [Related]

  • 17. CTP limitation increases expression of CTP synthase in Lactococcus lactis.
    Jørgensen CM, Hammer K, Martinussen J.
    J Bacteriol; 2003 Nov 15; 185(22):6562-74. PubMed ID: 14594829
    [Abstract] [Full Text] [Related]

  • 18. Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase.
    Iyengar A, Bearne SL.
    Biochem J; 2003 Feb 01; 369(Pt 3):497-507. PubMed ID: 12383057
    [Abstract] [Full Text] [Related]

  • 19. Expression of the pyrG gene determines the pool sizes of CTP and dCTP in Lactococcus lactis.
    Jørgensen CM, Hammer K, Jensen PR, Martinussen J.
    Eur J Biochem; 2004 Jun 01; 271(12):2438-45. PubMed ID: 15182359
    [Abstract] [Full Text] [Related]

  • 20. Structural basis for ligand binding modes of CTP synthase.
    Zhou X, Guo CJ, Chang CC, Zhong J, Hu HH, Lu GM, Liu JL.
    Proc Natl Acad Sci U S A; 2021 Jul 27; 118(30):. PubMed ID: 34301892
    [Abstract] [Full Text] [Related]

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