These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Thermodynamic consequences of grafting enhanced affinity toward the mutated antigen onto an antibody. The case of anti-lysozyme antibody, HyHEL-10. Nishimiya Y, Tsumoto K, Shiroishi M, Yutani K, Kumagai I. J Biol Chem; 2000 Apr 28; 275(17):12813-20. PubMed ID: 10777579 [Abstract] [Full Text] [Related]
4. Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,). Li Y, Li H, Smith-Gill SJ, Mariuzza RA. Biochemistry; 2000 May 30; 39(21):6296-309. PubMed ID: 10828942 [Abstract] [Full Text] [Related]
6. Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen. Li Y, Urrutia M, Smith-Gill SJ, Mariuzza RA. Biochemistry; 2003 Jan 14; 42(1):11-22. PubMed ID: 12515535 [Abstract] [Full Text] [Related]
7. Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfaces. Kondo H, Shiroishi M, Matsushima M, Tsumoto K, Kumagai I. J Biol Chem; 1999 Sep 24; 274(39):27623-31. PubMed ID: 10488102 [Abstract] [Full Text] [Related]
8. Modeling the binding sites of anti-hen egg white lysozyme antibodies HyHEL-8 and HyHEL-26: an insight into the molecular basis of antibody cross-reactivity and specificity. Mohan S, Sinha N, Smith-Gill SJ. Biophys J; 2003 Nov 24; 85(5):3221-36. PubMed ID: 14581222 [Abstract] [Full Text] [Related]
9. Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10. Nakanishi T, Tsumoto K, Yokota A, Kondo H, Kumagai I. Protein Sci; 2008 Feb 24; 17(2):261-70. PubMed ID: 18227432 [Abstract] [Full Text] [Related]
12. Interaction between the antigen and antibody is controlled by the constant domains: normal mode dynamics of the HEL-HyHEL-10 complex. Adachi M, Kurihara Y, Nojima H, Takeda-Shitaka M, Kamiya K, Umeyama H. Protein Sci; 2003 Oct 24; 12(10):2125-31. PubMed ID: 14500870 [Abstract] [Full Text] [Related]
13. Experimental analysis by site-directed mutagenesis of somatic mutation effects on affinity and fine specificity in antibodies specific for lysozyme. Lavoie TB, Drohan WN, Smith-Gill SJ. J Immunol; 1992 Jan 15; 148(2):503-13. PubMed ID: 1729369 [Abstract] [Full Text] [Related]
14. High-resolution mapping of the HyHEL-10 epitope of chicken lysozyme by site-directed mutagenesis. Kam-Morgan LN, Smith-Gill SJ, Taylor MG, Zhang L, Wilson AC, Kirsch JF. Proc Natl Acad Sci U S A; 1993 May 01; 90(9):3958-62. PubMed ID: 7683415 [Abstract] [Full Text] [Related]
17. Molecular dynamics simulation of a high-affinity antibody-protein complex: the binding site is a mosaic of locally flexible and preorganized rigid regions. Sinha N, Smith-Gill SJ. Cell Biochem Biophys; 2005 May 01; 43(2):253-73. PubMed ID: 16049350 [Abstract] [Full Text] [Related]
18. On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5. Novotny J, Bruccoleri RE, Saul FA. Biochemistry; 1989 May 30; 28(11):4735-49. PubMed ID: 2475171 [Abstract] [Full Text] [Related]
20. A mutational analysis of binding interactions in an antigen-antibody protein-protein complex. Dall'Acqua W, Goldman ER, Lin W, Teng C, Tsuchiya D, Li H, Ysern X, Braden BC, Li Y, Smith-Gill SJ, Mariuzza RA. Biochemistry; 1998 Jun 02; 37(22):7981-91. PubMed ID: 9609690 [Abstract] [Full Text] [Related] Page: [Next] [New Search]