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183 related items for PubMed ID: 12711631

  • 21. Antimitogenic and proapoptotic activities of methylseleninic acid in vascular endothelial cells and associated effects on PI3K-AKT, ERK, JNK and p38 MAPK signaling.
    Wang Z, Jiang C, Ganther H, Lü J.
    Cancer Res; 2001 Oct 01; 61(19):7171-8. PubMed ID: 11585751
    [Abstract] [Full Text] [Related]

  • 22. FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma.
    Liu Q, Zhao X, Frissora F, Ma Y, Santhanam R, Jarjoura D, Lehman A, Perrotti D, Chen CS, Dalton JT, Muthusamy N, Byrd JC.
    Blood; 2008 Jan 01; 111(1):275-84. PubMed ID: 17761520
    [Abstract] [Full Text] [Related]

  • 23. Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development.
    Burchert A, Wang Y, Cai D, von Bubnoff N, Paschka P, Müller-Brüsselbach S, Ottmann OG, Duyster J, Hochhaus A, Neubauer A.
    Leukemia; 2005 Oct 01; 19(10):1774-82. PubMed ID: 16136169
    [Abstract] [Full Text] [Related]

  • 24. FTY720 reduces migration and invasion of human glioblastoma cell lines via inhibiting the PI3K/AKT/mTOR/p70S6K signaling pathway.
    Zhang L, Wang H, Zhu J, Ding K, Xu J.
    Tumour Biol; 2014 Nov 01; 35(11):10707-14. PubMed ID: 25070489
    [Abstract] [Full Text] [Related]

  • 25. Ceramide produces apoptosis through induction of p27(kip1) by protein phosphatase 2A-dependent Akt dephosphorylation in PC-3 prostate cancer cells.
    Kim SW, Kim HJ, Chun YJ, Kim MY.
    J Toxicol Environ Health A; 2010 Nov 01; 73(21-22):1465-76. PubMed ID: 20954073
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  • 26. Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin.
    Hayakawa J, Ohmichi M, Kurachi H, Kanda Y, Hisamoto K, Nishio Y, Adachi K, Tasaka K, Kanzaki T, Murata Y.
    Cancer Res; 2000 Nov 01; 60(21):5988-94. PubMed ID: 11085518
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  • 27. Inactive caspase 3 activates Akt in human leukemia cells susceptible or resistant to apoptosis induced by phorbol ester.
    Hah JO, Lee KA, Choi YJ, Kim WD, Park JW, Kwon TK.
    Int J Oncol; 2003 May 01; 22(5):1111-6. PubMed ID: 12684678
    [Abstract] [Full Text] [Related]

  • 28. Role of AKT kinase in sphingosine-induced apoptosis in human hepatoma cells.
    Chang HC, Tsai LH, Chuang LY, Hung WC.
    J Cell Physiol; 2001 Aug 01; 188(2):188-93. PubMed ID: 11424085
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  • 29. Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process.
    Yu C, Rahmani M, Almenara J, Sausville EA, Dent P, Grant S.
    Oncogene; 2004 Feb 19; 23(7):1364-76. PubMed ID: 14647418
    [Abstract] [Full Text] [Related]

  • 30. Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt.
    Asnaghi L, Calastretti A, Bevilacqua A, D'Agnano I, Gatti G, Canti G, Delia D, Capaccioli S, Nicolin A.
    Oncogene; 2004 Jul 29; 23(34):5781-91. PubMed ID: 15208671
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  • 31. HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway.
    Kakazu A, Chandrasekher G, Bazan HE.
    Invest Ophthalmol Vis Sci; 2004 Oct 29; 45(10):3485-92. PubMed ID: 15452053
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  • 32. Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.
    Sinha D, Wang Z, Ruchalski KL, Levine JS, Krishnan S, Lieberthal W, Schwartz JH, Borkan SC.
    Am J Physiol Renal Physiol; 2005 Apr 29; 288(4):F703-13. PubMed ID: 15572521
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  • 33. FTY720 induces apoptosis in hepatocellular carcinoma cells through activation of protein kinase C delta signaling.
    Hung JH, Lu YS, Wang YC, Ma YH, Wang DS, Kulp SK, Muthusamy N, Byrd JC, Cheng AL, Chen CS.
    Cancer Res; 2008 Feb 15; 68(4):1204-12. PubMed ID: 18281497
    [Abstract] [Full Text] [Related]

  • 34. Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B.
    Fujita H, Utsumi T, Muranaka S, Ogino T, Yano H, Akiyama J, Yasuda T, Utsumi K.
    Biochem Pharmacol; 2005 Jun 15; 69(12):1773-84. PubMed ID: 15869745
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  • 35. Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies.
    Oaks JJ, Santhanam R, Walker CJ, Roof S, Harb JG, Ferenchak G, Eisfeld AK, Van Brocklyn JR, Briesewitz R, Saddoughi SA, Nagata K, Bittman R, Caligiuri MA, Abdel-Wahab O, Levine R, Arlinghaus RB, Quintas-Cardama A, Goldman JM, Apperley J, Reid A, Milojkovic D, Ziolo MT, Marcucci G, Ogretmen B, Neviani P, Perrotti D.
    Blood; 2013 Sep 12; 122(11):1923-34. PubMed ID: 23926298
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  • 36. Role of extracelluar regulated protein kinases in FTY720-induced apoptosis of leukemia cell lines HL-60 and U937.
    Li D, Zhang Y, Hu X, Cao W, Huang W.
    J Huazhong Univ Sci Technolog Med Sci; 2004 Sep 12; 24(1):45-7. PubMed ID: 15165113
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  • 37. Attenuation of small-for-size liver graft injury by FTY720: significance of cell-survival Akt signaling pathway.
    Zhao Y, Man K, Lo CM, Ng KT, Li XL, Sun CK, Lee TK, Dai XW, Fan ST.
    Am J Transplant; 2004 Sep 12; 4(9):1399-407. PubMed ID: 15307827
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  • 38. FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells.
    Wallington-Beddoe CT, Hewson J, Bradstock KF, Bendall LJ.
    Autophagy; 2011 Jul 12; 7(7):707-15. PubMed ID: 21460633
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  • 39. [Influence of PP2A activator on proliferation of HL-60 cells and analysis of PP2A activity changes in patients with acute myeloid leukemia].
    Yang Y, Li XQ, Huang Q, Huang SA.
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2011 Jun 12; 19(3):594-7. PubMed ID: 21729530
    [Abstract] [Full Text] [Related]

  • 40. PTH inactivates the AKT survival pathway in the colonic cell line Caco-2.
    Calvo N, de Boland AR, Gentili C.
    Biochim Biophys Acta; 2010 Mar 12; 1803(3):343-51. PubMed ID: 20005908
    [Abstract] [Full Text] [Related]

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