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802 related items for PubMed ID: 12717389

  • 1. Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.
    Koga H, Harada M, Ohtsubo M, Shishido S, Kumemura H, Hanada S, Taniguchi E, Yamashita K, Kumashiro R, Ueno T, Sata M.
    Hepatology; 2003 May; 37(5):1086-96. PubMed ID: 12717389
    [Abstract] [Full Text] [Related]

  • 2. Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines.
    Koga H, Sakisaka S, Harada M, Takagi T, Hanada S, Taniguchi E, Kawaguchi T, Sasatomi K, Kimura R, Hashimoto O, Ueno T, Yano H, Kojiro M, Sata M.
    Hepatology; 2001 May; 33(5):1087-97. PubMed ID: 11343236
    [Abstract] [Full Text] [Related]

  • 3. Growth arrest by troglitazone is mediated by p27Kip1 accumulation, which results from dual inhibition of proteasome activity and Skp2 expression in human hepatocellular carcinoma cells.
    Motomura W, Takahashi N, Nagamine M, Sawamukai M, Tanno S, Kohgo Y, Okumura T.
    Int J Cancer; 2004 Jan 01; 108(1):41-6. PubMed ID: 14618613
    [Abstract] [Full Text] [Related]

  • 4. Troglitazone but not rosiglitazone induces G1 cell cycle arrest and apoptosis in human and rat hepatoma cell lines.
    Bae MA, Rhee H, Song BJ.
    Toxicol Lett; 2003 Mar 20; 139(1):67-75. PubMed ID: 12595159
    [Abstract] [Full Text] [Related]

  • 5. Activation of peroxisome proliferator-activated receptor gamma by troglitazone inhibits cell growth through the increase of p27KiP1 in human. Pancreatic carcinoma cells.
    Motomura W, Okumura T, Takahashi N, Obara T, Kohgo Y.
    Cancer Res; 2000 Oct 01; 60(19):5558-64. PubMed ID: 11034103
    [Abstract] [Full Text] [Related]

  • 6. Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.
    Di Gennaro E, Barbarino M, Bruzzese F, De Lorenzo S, Caraglia M, Abbruzzese A, Avallone A, Comella P, Caponigro F, Pepe S, Budillon A.
    J Cell Physiol; 2003 Apr 01; 195(1):139-50. PubMed ID: 12599217
    [Abstract] [Full Text] [Related]

  • 7. Troglitazone induces G1 arrest by p27(Kip1) induction that is mediated by inhibition of proteasome in human gastric cancer cells.
    Takeuchi S, Okumura T, Motomura W, Nagamine M, Takahashi N, Kohgo Y.
    Jpn J Cancer Res; 2002 Jul 01; 93(7):774-82. PubMed ID: 12149143
    [Abstract] [Full Text] [Related]

  • 8. Troglitazone inhibits growth of MCF-7 breast carcinoma cells by targeting G1 cell cycle regulators.
    Yin F, Wakino S, Liu Z, Kim S, Hsueh WA, Collins AR, Van Herle AJ, Law RE.
    Biochem Biophys Res Commun; 2001 Sep 07; 286(5):916-22. PubMed ID: 11527386
    [Abstract] [Full Text] [Related]

  • 9. Differential effects of transforming growth factor on cell cycle regulatory molecules in human myeloid leukemia cells.
    Hu X, Zhang X, Zhong Q, Fisher AB, Bryington M, Zuckerman KS.
    Oncogene; 2001 Oct 18; 20(47):6840-50. PubMed ID: 11687963
    [Abstract] [Full Text] [Related]

  • 10. Accumulation of a form of p27(Kip1) not associated with Cdk-cyclin complexes in transforming growth factor-beta-arrested Mv1Lu cells.
    Taipale M, Tiihonen E, Heiskanen A, Laiho M.
    Exp Cell Res; 2000 Aug 25; 259(1):107-16. PubMed ID: 10942583
    [Abstract] [Full Text] [Related]

  • 11. Troglitazone inhibits tumor growth in hepatocellular carcinoma in vitro and in vivo.
    Yu J, Qiao L, Zimmermann L, Ebert MP, Zhang H, Lin W, Röcken C, Malfertheiner P, Farrell GC.
    Hepatology; 2006 Jan 25; 43(1):134-43. PubMed ID: 16374840
    [Abstract] [Full Text] [Related]

  • 12. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
    Patel V, Lahusen T, Leethanakul C, Igishi T, Kremer M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS, Senderowicz AM.
    Clin Cancer Res; 2002 Nov 25; 8(11):3549-60. PubMed ID: 12429646
    [Abstract] [Full Text] [Related]

  • 13. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S, Lowe M, Herliczek TW, Keyomarsi K.
    Oncogene; 1998 Nov 05; 17(18):2393-402. PubMed ID: 9811471
    [Abstract] [Full Text] [Related]

  • 14. Mimosine arrests cells in G1 by enhancing the levels of p27(Kip1).
    Wang G, Miskimins R, Miskimins WK.
    Exp Cell Res; 2000 Jan 10; 254(1):64-71. PubMed ID: 10623466
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
    Coppock DL, Buffolino P, Kopman C, Nathanson L.
    Exp Cell Res; 1995 Nov 10; 221(1):92-102. PubMed ID: 7589260
    [Abstract] [Full Text] [Related]

  • 16. Peroxisome proliferator-activated receptor gamma ligand troglitazone induces cell cycle arrest and apoptosis of hepatocellular carcinoma cell lines.
    Yoshizawa K, Cioca DP, Kawa S, Tanaka E, Kiyosawa K.
    Cancer; 2002 Nov 15; 95(10):2243-51. PubMed ID: 12412180
    [Abstract] [Full Text] [Related]

  • 17. Oncostatin M induces growth arrest by inhibition of Skp2, Cks1, and cyclin A expression and induced p21 expression.
    Halfter H, Friedrich M, Resch A, Kullmann M, Stögbauer F, Ringelstein EB, Hengst L.
    Cancer Res; 2006 Jul 01; 66(13):6530-9. PubMed ID: 16818624
    [Abstract] [Full Text] [Related]

  • 18. Increased cdc2 and cdk2 kinase activity by retinoid X receptor gamma-mediated transcriptional down-regulation of the cyclin-dependent kinase inhibitor p21Cip1/WAF1 correlates with terminal differentiation of squamous cell carcinoma lines.
    Crowe DL, Shuler CF.
    Cell Growth Differ; 1998 Aug 01; 9(8):619-27. PubMed ID: 9716179
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
    Lin R, Wang TT, Miller WH, White JH.
    Endocrinology; 2003 Mar 01; 144(3):749-53. PubMed ID: 12586749
    [Abstract] [Full Text] [Related]

  • 20. Limiting amounts of p27Kip1 correlates with constitutive activation of cyclin E-CDK2 complex in HTLV-I-transformed T-cells.
    Cereseto A, Washington Parks R, Rivadeneira E, Franchini G.
    Oncogene; 1999 Apr 15; 18(15):2441-50. PubMed ID: 10229195
    [Abstract] [Full Text] [Related]

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