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Journal Abstract Search

127 related items for PubMed ID: 12729656

  • 1. Piperazinyl-linked fluoroquinolone dimers possessing potent antibacterial activity against drug-resistant strains of Staphylococcus aureus.
    Kerns RJ, Rybak MJ, Kaatz GW, Vaka F, Cha R, Grucz RG, Diwadkar VU, Ward TD.
    Bioorg Med Chem Lett; 2003 May 19; 13(10):1745-9. PubMed ID: 12729656
    [Abstract] [Full Text] [Related]

  • 2. Structural features of piperazinyl-linked ciprofloxacin dimers required for activity against drug-resistant strains of Staphylococcus aureus.
    Kerns RJ, Rybak MJ, Kaatz GW, Vaka F, Cha R, Grucz RG, Diwadkar VU.
    Bioorg Med Chem Lett; 2003 Jul 07; 13(13):2109-12. PubMed ID: 12798315
    [Abstract] [Full Text] [Related]

  • 3. Relationship between mutations in the DNA gyrase and topoisomerase IV genes and nadifloxacin resistance in clinically isolated quinolone-resistant Staphylococcus aureus.
    Oizumi N, Kawabata S, Hirao M, Watanabe K, Okuno S, Fujiwara T, Kikuchi M.
    J Infect Chemother; 2001 Sep 07; 7(3):191-4. PubMed ID: 11810583
    [Abstract] [Full Text] [Related]

  • 4. Bactericidal activity and target preference of a piperazinyl-cross-linked ciprofloxacin dimer with Staphylococcus aureus and Escherichia coli.
    Zhao X, Quinn B, Kerns R, Drlica K.
    J Antimicrob Chemother; 2006 Dec 07; 58(6):1283-6. PubMed ID: 17003060
    [Abstract] [Full Text] [Related]

  • 5. Antimicrobial activity of Mimosa caesalpiniifolia Benth and its interaction with antibiotics against Staphylococcus aureus strains overexpressing efflux pump genes.
    Silva SWC, Monção NBN, Araújo BQ, Arcanjo DDR, Ferreira JHL, Lima Neto JS, Citó AMGL, de Siqueira Júnior JP, Kaatz GW, Barreto HM.
    Lett Appl Microbiol; 2019 Jul 07; 69(1):57-63. PubMed ID: 31002429
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and in vitro antibacterial activity of 7-(3-alkoxyimino-5-amino/methylaminopiperidin-1-yl)fluoroquinolone derivatives.
    Zhang Y, Li G, Liu M, You X, Feng L, Lv K, Cao J, Guo H.
    Bioorg Med Chem Lett; 2011 Feb 01; 21(3):928-31. PubMed ID: 21232952
    [Abstract] [Full Text] [Related]

  • 7. Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance.
    Sabatini S, Gosetto F, Iraci N, Barreca ML, Massari S, Sancineto L, Manfroni G, Tabarrini O, Dimovska M, Kaatz GW, Cecchetti V.
    J Med Chem; 2013 Jun 27; 56(12):4975-89. PubMed ID: 23710549
    [Abstract] [Full Text] [Related]

  • 8. 1-(1H-indol-3-yl)ethanamine derivatives as potent Staphylococcus aureus NorA efflux pump inhibitors.
    Hequet A, Burchak ON, Jeanty M, Guinchard X, Le Pihive E, Maigre L, Bouhours P, Schneider D, Maurin M, Paris JM, Denis JN, Jolivalt C.
    ChemMedChem; 2014 Jul 27; 9(7):1534-45. PubMed ID: 24677763
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of the NorA efflux pump of Staphylococcus aureus by synthetic riparins.
    Costa LM, de Macedo EV, Oliveira FA, Ferreira JH, Gutierrez SJ, Peláez WJ, Lima FC, de Siqueira Júnior JP, Coutinho HD, Kaatz GW, de Freitas RM, Barreto HM.
    J Appl Microbiol; 2016 Nov 27; 121(5):1312-1322. PubMed ID: 27537678
    [Abstract] [Full Text] [Related]

  • 10. Comparison of the nucleotide sequence and expression of norA genes and microbial susceptibility in 21 strains of Staphylococcus aureus.
    Noguchi N, Okada H, Narui K, Sasatsu M.
    Microb Drug Resist; 2004 Nov 27; 10(3):197-203. PubMed ID: 15383162
    [Abstract] [Full Text] [Related]

  • 11. Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump.
    Sabatini S, Gosetto F, Manfroni G, Tabarrini O, Kaatz GW, Patel D, Cecchetti V.
    J Med Chem; 2011 Aug 25; 54(16):5722-36. PubMed ID: 21751791
    [Abstract] [Full Text] [Related]

  • 12. First identification of boronic species as novel potential inhibitors of the Staphylococcus aureus NorA efflux pump.
    Fontaine F, Hequet A, Voisin-Chiret AS, Bouillon A, Lesnard A, Cresteil T, Jolivalt C, Rault S.
    J Med Chem; 2014 Mar 27; 57(6):2536-48. PubMed ID: 24499135
    [Abstract] [Full Text] [Related]

  • 13. Antimicrobial susceptibility of Staphylococcus species isolated from prosthetic joints with a focus on fluoroquinolone-resistance mechanisms.
    Darboe KS, Oh TH, Choi SM, Kim HK, Kim SE, Kim UJ, Kang SJ, Jang HC, Jung SI, Park KH.
    Diagn Microbiol Infect Dis; 2021 Jan 27; 99(1):115173. PubMed ID: 32992142
    [Abstract] [Full Text] [Related]

  • 14. New fluoroquinolone compounds with endo-nortropine derivatives at C-7 position show antibacterial activity against fluoroquinolone-resistant strains of Staphylococcus aureus.
    Salunke RA, Shukla M, Kaul G, Bansal BR, Chopra S, Chhibber M.
    Chem Biol Drug Des; 2019 Sep 27; 94(3):1626-1633. PubMed ID: 30860312
    [Abstract] [Full Text] [Related]

  • 15. Antimicrobial activity of Phyllanthus amarus Schumach. & Thonn and inhibition of the NorA efflux pump of Staphylococcus aureus by Phyllanthin.
    Braga Ribeiro AM, Sousa JN, Costa LM, Oliveira FAA, Dos Santos RC, Silva Nunes AS, da Silva WO, Marques Cordeiro PJ, de Sousa Lima Neto J, de Siqueira-Júnior JP, Kaatz GW, Barreto HM, de Oliveira AP.
    Microb Pathog; 2019 May 27; 130():242-246. PubMed ID: 30876871
    [Abstract] [Full Text] [Related]

  • 16. Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.
    Skepper CK, Armstrong D, Balibar CJ, Bauer D, Bellamacina C, Benton BM, Bussiere D, De Pascale G, De Vicente J, Dean CR, Dhumale B, Fisher LM, Fuller J, Fulsunder M, Holder LM, Hu C, Kantariya B, Lapointe G, Leeds JA, Li X, Lu P, Lvov A, Ma S, Madhavan S, Malekar S, McKenney D, Mergo W, Metzger L, Moser HE, Mutnick D, Noeske J, Osborne C, Patel A, Patel D, Patel T, Prajapati K, Prosen KR, Reck F, Richie DL, Rico A, Sanderson MR, Satasia S, Sawyer WS, Selvarajah J, Shah N, Shanghavi K, Shu W, Thompson KV, Traebert M, Vala A, Vala L, Veselkov DA, Vo J, Wang M, Widya M, Williams SL, Xu Y, Yue Q, Zang R, Zhou B, Rivkin A.
    J Med Chem; 2020 Jul 23; 63(14):7773-7816. PubMed ID: 32634310
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of amides from (E)-3-(1-chloro-3,4-dihydronaphthalen-2-yl)acrylic acid and substituted amino acid esters as NorA efflux pump inhibitors of Staphylococcus aureus.
    Rath SK, Singh S, Kumar S, Wani NA, Rai R, Koul S, Khan IA, Sangwan PL.
    Bioorg Med Chem; 2019 Jan 15; 27(2):343-353. PubMed ID: 30552006
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps.
    German N, Wei P, Kaatz GW, Kerns RJ.
    Eur J Med Chem; 2008 Nov 15; 43(11):2453-63. PubMed ID: 18358571
    [Abstract] [Full Text] [Related]

  • 19. A novel bi-functional chalcone inhibits multi-drug resistant Staphylococcus aureus and potentiates the activity of fluoroquinolones.
    Gupta VK, Gaur R, Sharma A, Akther J, Saini M, Bhakuni RS, Pathania R.
    Bioorg Chem; 2019 Mar 15; 83():214-225. PubMed ID: 30380450
    [Abstract] [Full Text] [Related]

  • 20. Novel structural analogues of piperine as inhibitors of the NorA efflux pump of Staphylococcus aureus.
    Kumar A, Khan IA, Koul S, Koul JL, Taneja SC, Ali I, Ali F, Sharma S, Mirza ZM, Kumar M, Sangwan PL, Gupta P, Thota N, Qazi GN.
    J Antimicrob Chemother; 2008 Jun 15; 61(6):1270-6. PubMed ID: 18334493
    [Abstract] [Full Text] [Related]

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