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392 related items for PubMed ID: 12734391

  • 1. Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons.
    Takada Y, Yonezawa A, Kume T, Katsuki H, Kaneko S, Sugimoto H, Akaike A.
    J Pharmacol Exp Ther; 2003 Aug; 306(2):772-7. PubMed ID: 12734391
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of neuroprotection by donepezil pretreatment in rat cortical neurons chronically treated with donepezil.
    Takada-Takatori Y, Kume T, Ohgi Y, Izumi Y, Niidome T, Fujii T, Sugimoto H, Akaike A.
    J Neurosci Res; 2008 Dec; 86(16):3575-83. PubMed ID: 18655200
    [Abstract] [Full Text] [Related]

  • 3. Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade.
    Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Sugimoto H, Akaike A.
    Neuropharmacology; 2006 Sep; 51(3):474-86. PubMed ID: 16762377
    [Abstract] [Full Text] [Related]

  • 4. 5-Iodo-A-85380, a specific ligand for alpha 4 beta 2 nicotinic acetylcholine receptors, prevents glutamate neurotoxicity in rat cortical cultured neurons.
    Ueda M, Iida Y, Kitamura Y, Kawashima H, Ogawa M, Magata Y, Saji H.
    Brain Res; 2008 Mar 14; 1199():46-52. PubMed ID: 18269932
    [Abstract] [Full Text] [Related]

  • 5. Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity.
    Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Niidome T, Sugimoto H, Fujii T, Okabe S, Akaike A.
    Eur J Pharmacol; 2006 Nov 07; 549(1-3):19-26. PubMed ID: 16996497
    [Abstract] [Full Text] [Related]

  • 6. New insight into the functional role of acetylcholine in developing embryonic rat retinal neurons.
    Yasuyoshi H, Kashii S, Kikuchi M, Zhang S, Honda Y, Akaike A.
    Invest Ophthalmol Vis Sci; 2002 Feb 07; 43(2):446-51. PubMed ID: 11818389
    [Abstract] [Full Text] [Related]

  • 7. Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons.
    Kume T, Sugimoto M, Takada Y, Yamaguchi T, Yonezawa A, Katsuki H, Sugimoto H, Akaike A.
    Eur J Pharmacol; 2005 Dec 19; 527(1-3):77-85. PubMed ID: 16313899
    [Abstract] [Full Text] [Related]

  • 8. Donepezil attenuates excitotoxic damage induced by membrane depolarization of cortical neurons exposed to veratridine.
    Akasofu S, Sawada K, Kosasa T, Hihara H, Ogura H, Akaike A.
    Eur J Pharmacol; 2008 Jul 07; 588(2-3):189-97. PubMed ID: 18508044
    [Abstract] [Full Text] [Related]

  • 9. Preclinical evidence of neuroprotection by cholinesterase inhibitors.
    Akaike A.
    Alzheimer Dis Assoc Disord; 2006 Jul 07; 20(2 Suppl 1):S8-11. PubMed ID: 16772755
    [Abstract] [Full Text] [Related]

  • 10. [Mechanisms of neuroprotective effects of therapeutic acetylcholinesterase inhibitors used in treatment of Alzheimer's disease].
    Takatori Y.
    Yakugaku Zasshi; 2006 Aug 07; 126(8):607-16. PubMed ID: 16880719
    [Abstract] [Full Text] [Related]

  • 11. Protective effect of donepezil in primary-cultured rat cortical neurons exposed to N-methyl-d-aspartate (NMDA) toxicity.
    Akasofu S, Kimura M, Kosasa T, Ogura H, Sawada K.
    Eur J Pharmacol; 2006 Jan 20; 530(3):215-22. PubMed ID: 16406045
    [Abstract] [Full Text] [Related]

  • 12. Study of neuroprotection of donepezil, a therapy for Alzheimer's disease.
    Akasofu S, Kimura M, Kosasa T, Sawada K, Ogura H.
    Chem Biol Interact; 2008 Sep 25; 175(1-3):222-6. PubMed ID: 18571635
    [Abstract] [Full Text] [Related]

  • 13. Neuroprotective effects of donepezil through inhibition of GSK-3 activity in amyloid-beta-induced neuronal cell death.
    Noh MY, Koh SH, Kim Y, Kim HY, Cho GW, Kim SH.
    J Neurochem; 2009 Mar 25; 108(5):1116-25. PubMed ID: 19077054
    [Abstract] [Full Text] [Related]

  • 14. Neuroprotective effect of donepezil, a nicotinic acetylcholine-receptor activator, on cerebral infarction in rats.
    Fujiki M, Kobayashi H, Uchida S, Inoue R, Ishii K.
    Brain Res; 2005 May 10; 1043(1-2):236-41. PubMed ID: 15862539
    [Abstract] [Full Text] [Related]

  • 15. Comparison of donepezil and memantine for protective effect against amyloid-beta(1-42) toxicity in rat septal neurons.
    Kimura M, Komatsu H, Ogura H, Sawada K.
    Neurosci Lett; 2005 Dec 31; 391(1-2):17-21. PubMed ID: 16154269
    [Abstract] [Full Text] [Related]

  • 16. Protective effect of donepezil against Abeta(1-40) neurotoxicity in rat septal neurons.
    Kimura M, Akasofu S, Ogura H, Sawada K.
    Brain Res; 2005 Jun 14; 1047(1):72-84. PubMed ID: 15893738
    [Abstract] [Full Text] [Related]

  • 17. Galantamine modulates nicotinic receptor and blocks Abeta-enhanced glutamate toxicity.
    Kihara T, Sawada H, Nakamizo T, Kanki R, Yamashita H, Maelicke A, Shimohama S.
    Biochem Biophys Res Commun; 2004 Dec 17; 325(3):976-82. PubMed ID: 15541385
    [Abstract] [Full Text] [Related]

  • 18. Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity.
    Kihara T, Shimohama S, Sawada H, Kimura J, Kume T, Kochiyama H, Maeda T, Akaike A.
    Ann Neurol; 1997 Aug 17; 42(2):159-63. PubMed ID: 9266724
    [Abstract] [Full Text] [Related]

  • 19. Protective effect of bradykinin against glutamate neurotoxicity in cultured rat retinal neurons.
    Yasuyoshi H, Kashii S, Zhang S, Nishida A, Yamauchi T, Honda Y, Asano Y, Sato S, Akaike A.
    Invest Ophthalmol Vis Sci; 2000 Jul 17; 41(8):2273-8. PubMed ID: 10892873
    [Abstract] [Full Text] [Related]

  • 20. Neuroprotective and antiamnesic effect of donepezil, a nicotinic acetylcholine-receptor activator, on rats with concussive mild traumatic brain injury.
    Fujiki M, Kubo T, Kamida T, Sugita K, Hikawa T, Abe T, Ishii K, Kobayashi H.
    J Clin Neurosci; 2008 Jul 17; 15(7):791-6. PubMed ID: 18407501
    [Abstract] [Full Text] [Related]


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