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228 related items for PubMed ID: 12741817

  • 1. Identification of the residues in the helix F/G loop important to catalytic function of membrane-bound prostacyclin synthase.
    Deng H, Wu J, So SP, Ruan KH.
    Biochemistry; 2003 May 20; 42(19):5609-17. PubMed ID: 12741817
    [Abstract] [Full Text] [Related]

  • 2. Topology of catalytic portion of prostaglandin I(2) synthase: identification by molecular modeling-guided site-specific antibodies.
    Lin YZ, Deng H, Ruan KH.
    Arch Biochem Biophys; 2000 Jul 15; 379(2):188-97. PubMed ID: 10898934
    [Abstract] [Full Text] [Related]

  • 3. Determination of the membrane contact residues and solution structure of the helix F/G loop of prostaglandin I2 synthase.
    Wu J, So SP, Ruan KH.
    Arch Biochem Biophys; 2003 Mar 01; 411(1):27-35. PubMed ID: 12590920
    [Abstract] [Full Text] [Related]

  • 4. Substrate access channel topology in membrane-bound prostacyclin synthase.
    Deng H, Huang A, So SP, Lin YZ, Ruan KH.
    Biochem J; 2002 Mar 15; 362(Pt 3):545-51. PubMed ID: 11879180
    [Abstract] [Full Text] [Related]

  • 5. The N-terminal membrane anchor domain of the membrane-bound prostacyclin synthase involved in the substrate presentation of the coupling reaction with cyclooxygenase.
    Ruan KH, Deng H, Wu J, So SP.
    Arch Biochem Biophys; 2005 Mar 15; 435(2):372-81. PubMed ID: 15708381
    [Abstract] [Full Text] [Related]

  • 6. Characterization of the substrate mimic bound to engineered prostacyclin synthase in solution using high-resolution NMR spectroscopy and mutagenesis: implication of the molecular mechanism in biosynthesis of prostacyclin.
    Ruan KH, Wu J, Cervantes V.
    Biochemistry; 2008 Jan 15; 47(2):680-8. PubMed ID: 18081314
    [Abstract] [Full Text] [Related]

  • 7. Structural and functional characterization of the first intracellular loop of human thromboxane A2 receptor.
    Geng L, Wu J, So SP, Huang G, Ruan KH.
    Arch Biochem Biophys; 2004 Mar 15; 423(2):253-65. PubMed ID: 15001390
    [Abstract] [Full Text] [Related]

  • 8. Molecular cloning and characterization of bovine prostacyclin synthase.
    Pereira B, Wu KK, Wang LH.
    Biochem Biophys Res Commun; 1994 Aug 30; 203(1):59-66. PubMed ID: 8074709
    [Abstract] [Full Text] [Related]

  • 9. Cellular and molecular biology of prostacyclin synthase.
    Wu KK, Liou JY.
    Biochem Biophys Res Commun; 2005 Dec 09; 338(1):45-52. PubMed ID: 16115610
    [Abstract] [Full Text] [Related]

  • 10. A profile of the residues in the first intracellular loop critical for Gs-mediated signaling of human prostacyclin receptor characterized by an integrative approach of NMR-experiment and mutagenesis.
    Zhang L, Huang G, Wu J, Ruan KH.
    Biochemistry; 2005 Aug 30; 44(34):11389-401. PubMed ID: 16114876
    [Abstract] [Full Text] [Related]

  • 11. The roles of active-site residues in the catalytic mechanism of trans-3-chloroacrylic acid dehalogenase: a kinetic, NMR, and mutational analysis.
    Azurmendi HF, Wang SC, Massiah MA, Poelarends GJ, Whitman CP, Mildvan AS.
    Biochemistry; 2004 Apr 13; 43(14):4082-91. PubMed ID: 15065850
    [Abstract] [Full Text] [Related]

  • 12. NMR studies of the secondary structure in solution and the steroid binding site of delta5-3-ketosteroid isomerase in complexes with diamagnetic and paramagnetic steroids.
    Zhao Q, Abeygunawardana C, Mildvan AS.
    Biochemistry; 1997 Mar 25; 36(12):3458-72. PubMed ID: 9131995
    [Abstract] [Full Text] [Related]

  • 13. Structural characterization of the interaction of the delta and alpha subunits of the Escherichia coli F1F0-ATP synthase by NMR spectroscopy.
    Wilkens S, Borchardt D, Weber J, Senior AE.
    Biochemistry; 2005 Sep 06; 44(35):11786-94. PubMed ID: 16128580
    [Abstract] [Full Text] [Related]

  • 14. Characterization of the secondary structure and membrane interaction of the putative membrane anchor domains of prostaglandin I2 synthase and cytochrome P450 2C1.
    Lin Y, Wu KK, Ruan KH.
    Arch Biochem Biophys; 1998 Apr 01; 352(1):78-84. PubMed ID: 9521818
    [Abstract] [Full Text] [Related]

  • 15. NMR solution structure of a cytoplasmic surface loop of the human red cell anion transporter, band 3.
    Askin D, Bloomberg GB, Chambers EJ, Tanner MJ.
    Biochemistry; 1998 Aug 18; 37(33):11670-8. PubMed ID: 9709005
    [Abstract] [Full Text] [Related]

  • 16. The NMR solution structure of a mutant of the Max b/HLH/LZ free of DNA: insights into the specific and reversible DNA binding mechanism of dimeric transcription factors.
    Sauvé S, Tremblay L, Lavigne P.
    J Mol Biol; 2004 Sep 17; 342(3):813-32. PubMed ID: 15342239
    [Abstract] [Full Text] [Related]

  • 17. Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450.
    Matsunaga I, Ueda A, Sumimoto T, Ichihara K, Ayata M, Ogura H.
    Arch Biochem Biophys; 2001 Oct 01; 394(1):45-53. PubMed ID: 11566026
    [Abstract] [Full Text] [Related]

  • 18. Glycine-rich loop of mitochondrial processing peptidase alpha-subunit is responsible for substrate recognition by a mechanism analogous to mitochondrial receptor Tom20.
    Dvoráková-Holá K, Matusková A, Kubala M, Otyepka M, Kucera T, Vecer J, Herman P, Parkhomenko N, Kutejova E, Janata J.
    J Mol Biol; 2010 Mar 12; 396(5):1197-210. PubMed ID: 20053354
    [Abstract] [Full Text] [Related]

  • 19. Arginines 97 and 108 in CYP2C9 are important determinants of the catalytic function.
    Ridderström M, Masimirembwa C, Trump-Kallmeyer S, Ahlefelt M, Otter C, Andersson TB.
    Biochem Biophys Res Commun; 2000 Apr 21; 270(3):983-7. PubMed ID: 10772937
    [Abstract] [Full Text] [Related]

  • 20. Probing the interaction between prostacyclin synthase and prostaglandin H2 analogues or inhibitors via a combination of resonance Raman spectroscopy and molecular dynamics simulation approaches.
    Chao WC, Lu JF, Wang JS, Yang HC, Chen HH, Lan YK, Yu YC, Chou PT, Wang LH.
    J Am Chem Soc; 2011 Nov 23; 133(46):18870-9. PubMed ID: 21978190
    [Abstract] [Full Text] [Related]

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