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Journal Abstract Search

169 related items for PubMed ID: 12755596

  • 1.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 2. Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens.
    Wang M, Cheng G, Sturla SJ, Shi Y, McIntee EJ, Villalta PW, Upadhyaya P, Hecht SS.
    Chem Res Toxicol; 2003 May; 16(5):616-26. PubMed ID: 12755591
    [Abstract] [Full Text] [Related]

  • 3. Identification of O2-substituted pyrimidine adducts formed in reactions of 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone and 4-(acetoxymethylnitros- amino)-1-(3-pyridyl)-1-butanol with DNA.
    Hecht SS, Villalta PW, Sturla SJ, Cheng G, Yu N, Upadhyaya P, Wang M.
    Chem Res Toxicol; 2004 May; 17(5):588-97. PubMed ID: 15144215
    [Abstract] [Full Text] [Related]

  • 4. Mass spectrometric analysis of relative levels of pyridyloxobutylation adducts formed in the reaction of DNA with a chemically activated form of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Sturla SJ, Scott J, Lao Y, Hecht SS, Villalta PW.
    Chem Res Toxicol; 2005 Jun; 18(6):1048-55. PubMed ID: 15962940
    [Abstract] [Full Text] [Related]

  • 5. Mass spectrometric analysis of 4-hydroxy-1-(3-pyridyl)-1-butanone-releasing DNA adducts in human lung.
    Hölzle D, Schlöbe D, Tricker AR, Richter E.
    Toxicology; 2007 Apr 11; 232(3):277-85. PubMed ID: 17321028
    [Abstract] [Full Text] [Related]

  • 6. Stereoselective metabolism of nicotine and tobacco-specific N-nitrosamines to 4-hydroxy-4-(3-pyridyl)butanoic acid in rats.
    Trushin N, Hecht SS.
    Chem Res Toxicol; 1999 Feb 11; 12(2):164-71. PubMed ID: 10027794
    [Abstract] [Full Text] [Related]

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  • 8. 4-Hydroxy-1-(3-pyridyl)-1-butanone-hemoglobin adducts as biomarkers of exposure to tobacco smoke: validation of a method to be used in multicenter studies.
    Atawodi SE, Lea S, Nyberg F, Mukeria A, Constantinescu V, Ahrens W, Brueske-Hohlfeld I, Fortes C, Boffetta P, Friesen MD.
    Cancer Epidemiol Biomarkers Prev; 1998 Sep 11; 7(9):817-21. PubMed ID: 9752992
    [Abstract] [Full Text] [Related]

  • 9.
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  • 10. Detection and quantification of 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB) from smoker albumin and its potential as a surrogate biomarker of tobacco-specific nitrosamines exposure and bioactivation.
    Wang Y, Narayanapillai SC, Hu Q, Fujioka N, Xing C.
    Toxicol Lett; 2019 Sep 01; 311():11-16. PubMed ID: 31026483
    [Abstract] [Full Text] [Related]

  • 11. 4-Hydroxy-1-(3-pyridyl)-1-butanone-releasing DNA adducts in lung, lower esophagus and cardia of sudden death victims.
    Schlöbe D, Hölzle D, Hatz D, von Meyer L, Tricker AR, Richter E.
    Toxicology; 2008 Mar 12; 245(1-2):154-61. PubMed ID: 18243467
    [Abstract] [Full Text] [Related]

  • 12. Pyridyloxobutylation of guanine residues by 4-[(acetoxymethyl)nitrosamino]-1-(3-pyridyl)-1-butanone generates substrates of O6-alkylguanine-DNA alkyltransferase.
    Liu XK, Spratt TE, Murphy SE, Peterson LA.
    Chem Res Toxicol; 1996 Sep 12; 9(6):949-53. PubMed ID: 8870981
    [Abstract] [Full Text] [Related]

  • 13. Evidence that a hemoglobin adduct of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a 4-(3-pyridyl)-4-oxobutyl carboxylic acid ester.
    Carmella SG, Kagan SS, Hecht SS.
    Chem Res Toxicol; 1992 Sep 12; 5(1):76-80. PubMed ID: 1581541
    [Abstract] [Full Text] [Related]

  • 14. Acute and subacute effects of tobacco alkaloids, tobacco-specific nitrosamines and phenethyl isothiocyanate on N'-nitrosonornicotine metabolism in rats.
    Tyroller S, Zwickenpflug W, Thalheim C, Richter E.
    Toxicology; 2005 Nov 15; 215(3):245-53. PubMed ID: 16118032
    [Abstract] [Full Text] [Related]

  • 15. Two types of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone hemoglobin adducts, from metabolites which migrate into or are formed in red blood cells.
    Murphy SE, Coletta KA.
    Cancer Res; 1993 Feb 15; 53(4):777-83. PubMed ID: 8428358
    [Abstract] [Full Text] [Related]

  • 16. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM, Kenney PM, Peterson LA.
    Chem Res Toxicol; 2003 Jan 15; 16(1):1-6. PubMed ID: 12693024
    [Abstract] [Full Text] [Related]

  • 17. Investigation of the reaction of myosmine with sodium nitrite in vitro and in rats.
    Hecht SS, Han S, Kenney PM, Wang M, Lindgren B, Wang Y, Lao Y, Hochalter JB, Upadhyaya P.
    Chem Res Toxicol; 2007 Mar 15; 20(3):543-9. PubMed ID: 17291014
    [Abstract] [Full Text] [Related]

  • 18. Pyridyloxobutyl adduct O6-[4-oxo-4-(3-pyridyl)butyl]guanine is present in 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-treated DNA and is a substrate for O6-alkylguanine-DNA alkyltransferase.
    Wang L, Spratt TE, Liu XK, Hecht SS, Pegg AE, Peterson LA.
    Chem Res Toxicol; 1997 May 15; 10(5):562-7. PubMed ID: 9168254
    [Abstract] [Full Text] [Related]

  • 19. Formation of hemoglobin adducts upon treatment of F344 rats with the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine.
    Carmella SG, Hecht SS.
    Cancer Res; 1987 May 15; 47(10):2626-30. PubMed ID: 3567895
    [Abstract] [Full Text] [Related]

  • 20. Tobacco-specific nitrosamine adducts: studies in laboratory animals and humans.
    Hecht SS, Carmella SG, Foiles PG, Murphy SE, Peterson LA.
    Environ Health Perspect; 1993 Mar 15; 99():57-63. PubMed ID: 8319660
    [Abstract] [Full Text] [Related]

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