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671 related items for PubMed ID: 12759354

  • 1. Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.
    Lekmine F, Uddin S, Sassano A, Parmar S, Brachmann SM, Majchrzak B, Sonenberg N, Hay N, Fish EN, Platanias LC.
    J Biol Chem; 2003 Jul 25; 278(30):27772-80. PubMed ID: 12759354
    [Abstract] [Full Text] [Related]

  • 2. Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells.
    Parmar S, Smith J, Sassano A, Uddin S, Katsoulidis E, Majchrzak B, Kambhampati S, Eklund EA, Tallman MS, Fish EN, Platanias LC.
    Blood; 2005 Oct 01; 106(7):2436-43. PubMed ID: 15790787
    [Abstract] [Full Text] [Related]

  • 3. Interferon-gamma engages the p70 S6 kinase to regulate phosphorylation of the 40S S6 ribosomal protein.
    Lekmine F, Sassano A, Uddin S, Smith J, Majchrzak B, Brachmann SM, Hay N, Fish EN, Platanias LC.
    Exp Cell Res; 2004 Apr 15; 295(1):173-82. PubMed ID: 15051500
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1.
    El-Chaâr D, Gagnon A, Sorisky A.
    Int J Obes Relat Metab Disord; 2004 Feb 15; 28(2):191-8. PubMed ID: 14970836
    [Abstract] [Full Text] [Related]

  • 5. Regulatory effects of mammalian target of rapamycin-activated pathways in type I and II interferon signaling.
    Kaur S, Lal L, Sassano A, Majchrzak-Kita B, Srikanth M, Baker DP, Petroulakis E, Hay N, Sonenberg N, Fish EN, Platanias LC.
    J Biol Chem; 2007 Jan 19; 282(3):1757-68. PubMed ID: 17114181
    [Abstract] [Full Text] [Related]

  • 6. Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.
    Shi Y, Hsu JH, Hu L, Gera J, Lichtenstein A.
    J Biol Chem; 2002 May 03; 277(18):15712-20. PubMed ID: 11872747
    [Abstract] [Full Text] [Related]

  • 7. Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells.
    Lal L, Li Y, Smith J, Sassano A, Uddin S, Parmar S, Tallman MS, Minucci S, Hay N, Platanias LC.
    Blood; 2005 Feb 15; 105(4):1669-77. PubMed ID: 15471950
    [Abstract] [Full Text] [Related]

  • 8. Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.
    Pham PT, Heydrick SJ, Fox HL, Kimball SR, Jefferson LS, Lynch CJ.
    J Cell Biochem; 2000 Sep 07; 79(3):427-41. PubMed ID: 10972980
    [Abstract] [Full Text] [Related]

  • 9. 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway.
    Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N.
    Genes Dev; 1998 Feb 15; 12(4):502-13. PubMed ID: 9472019
    [Abstract] [Full Text] [Related]

  • 10. Translational homeostasis: eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities.
    Khaleghpour K, Pyronnet S, Gingras AC, Sonenberg N.
    Mol Cell Biol; 1999 Jun 15; 19(6):4302-10. PubMed ID: 10330171
    [Abstract] [Full Text] [Related]

  • 11. ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells.
    Hafizi S, Wang X, Chester AH, Yacoub MH, Proud CG.
    Am J Physiol Heart Circ Physiol; 2004 Sep 15; 287(3):H1232-8. PubMed ID: 15317677
    [Abstract] [Full Text] [Related]

  • 12. Activation of mRNA translation in rat cardiac myocytes by insulin involves multiple rapamycin-sensitive steps.
    Wang L, Wang X, Proud CG.
    Am J Physiol Heart Circ Physiol; 2000 Apr 15; 278(4):H1056-68. PubMed ID: 10749698
    [Abstract] [Full Text] [Related]

  • 13. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1.
    Burnett PE, Barrow RK, Cohen NA, Snyder SH, Sabatini DM.
    Proc Natl Acad Sci U S A; 1998 Feb 17; 95(4):1432-7. PubMed ID: 9465032
    [Abstract] [Full Text] [Related]

  • 14. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism.
    Hara K, Yonezawa K, Weng QP, Kozlowski MT, Belham C, Avruch J.
    J Biol Chem; 1998 Jun 05; 273(23):14484-94. PubMed ID: 9603962
    [Abstract] [Full Text] [Related]

  • 15. Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR.
    Dutton A, Reynolds GM, Dawson CW, Young LS, Murray PG.
    J Pathol; 2005 Mar 05; 205(4):498-506. PubMed ID: 15714459
    [Abstract] [Full Text] [Related]

  • 16. Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
    Bishop JD, Nien WL, Dauphinee SM, Too CK.
    J Endocrinol; 2006 Aug 05; 190(2):307-12. PubMed ID: 16899564
    [Abstract] [Full Text] [Related]

  • 17. Cytoplasmic-nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation.
    Kim JE, Chen J.
    Proc Natl Acad Sci U S A; 2000 Dec 19; 97(26):14340-5. PubMed ID: 11114166
    [Abstract] [Full Text] [Related]

  • 18. mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control.
    Polakiewicz RD, Schieferl SM, Gingras AC, Sonenberg N, Comb MJ.
    J Biol Chem; 1998 Sep 04; 273(36):23534-41. PubMed ID: 9722592
    [Abstract] [Full Text] [Related]

  • 19. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway.
    Nathan CO, Amirghahari N, Abreo F, Rong X, Caldito G, Jones ML, Zhou H, Smith M, Kimberly D, Glass J.
    Clin Cancer Res; 2004 Sep 01; 10(17):5820-7. PubMed ID: 15355912
    [Abstract] [Full Text] [Related]

  • 20. Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway.
    Thyrell L, Hjortsberg L, Arulampalam V, Panaretakis T, Uhles S, Dagnell M, Zhivotovsky B, Leibiger I, Grandér D, Pokrovskaja K.
    J Biol Chem; 2004 Jun 04; 279(23):24152-62. PubMed ID: 15056668
    [Abstract] [Full Text] [Related]

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