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Journal Abstract Search


91 related items for PubMed ID: 12761496

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  • 2. Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity.
    Giannakakou P, Robey R, Fojo T, Blagosklonny MV.
    Oncogene; 2001 Jun 28; 20(29):3806-13. PubMed ID: 11439344
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  • 5. Rapamycin and p53 act on different pathways to induce G1 arrest in mammalian cells.
    Metcalfe SM, Canman CE, Milner J, Morris RE, Goldman S, Kastan MB.
    Oncogene; 1997 Oct 02; 15(14):1635-42. PubMed ID: 9349496
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  • 7. Mechanisms of Taxol-induced cell death are concentration dependent.
    Torres K, Horwitz SB.
    Cancer Res; 1998 Aug 15; 58(16):3620-6. PubMed ID: 9721870
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  • 10. TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest.
    Schneider L, Essmann F, Kletke A, Rio P, Hanenberg H, Schulze-Osthoff K, Nürnberg B, Piekorz RP.
    Oncogene; 2008 Jan 03; 27(1):116-25. PubMed ID: 17599038
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  • 12. Perifosine, a novel alkylphospholipid, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway, leading to loss in cyclin-dependent kinase activity and cell cycle arrest.
    Patel V, Lahusen T, Sy T, Sausville EA, Gutkind JS, Senderowicz AM.
    Cancer Res; 2002 Mar 01; 62(5):1401-9. PubMed ID: 11888912
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  • 13. Taxol induction of p21WAF1 and p53 requires c-raf-1.
    Blagosklonny MV, Schulte TW, Nguyen P, Mimnaugh EG, Trepel J, Neckers L.
    Cancer Res; 1995 Oct 15; 55(20):4623-6. PubMed ID: 7553639
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  • 15. Paclitaxel selects for mutant or pseudo-null p53 in drug resistance associated with tubulin mutations in human cancer.
    Giannakakou P, Poy G, Zhan Z, Knutsen T, Blagosklonny MV, Fojo T.
    Oncogene; 2000 Jun 22; 19(27):3078-85. PubMed ID: 10871860
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  • 16. Inactivation of wild-type p53 by a dominant negative mutant renders MCF-7 cells resistant to tubulin-binding agent cytotoxicity.
    Galmarini CM, Falette N, Tabone E, Levrat C, Britten R, Voorzanger-Rousselot N, Roesch-Gateau O, Vanier-Viornery A, Puisieux A, Dumontet C.
    Br J Cancer; 2001 Sep 14; 85(6):902-8. PubMed ID: 11556844
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  • 17. Characterization of adriamycin-induced G2 arrest and its abrogation by caffeine in FL-amnion cells with or without p53.
    Minemoto Y, Gannon J, Masutani M, Nakagama H, Sasagawa T, Inoue M, Masamune Y, Yamashita K.
    Exp Cell Res; 2001 Jan 01; 262(1):37-48. PubMed ID: 11120603
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  • 18. Flavopiridol inversely affects p21(WAF1/CIP1) and p53 and protects p21-sensitive cells from paclitaxel.
    Blagosklonny MV, Darzynkiewicz Z, Figg WD.
    Cancer Biol Ther; 2002 Jan 01; 1(4):420-5. PubMed ID: 12432259
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  • 19. Overexpression of p21(waf1) decreases G2-M arrest and apoptosis induced by paclitaxel in human sarcoma cells lacking both p53 and functional Rb protein.
    Li W, Fan J, Banerjee D, Bertino JR.
    Mol Pharmacol; 1999 Jun 01; 55(6):1088-93. PubMed ID: 10347252
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  • 20. Cytoplasmic p21 is responsible for paclitaxel resistance in ovarian cancer A2780 cells.
    Xia X, Ji T, Liu R, Weng Y, Fang Y, Wang Z, Xu H.
    Eur J Gynaecol Oncol; 2015 Jun 01; 36(6):662-6. PubMed ID: 26775347
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