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403 related items for PubMed ID: 12765951

  • 1. Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice.
    Liu Y, Nakagawa Y, Wang Y, Li R, Li X, Ohzeki T, Friedman TC.
    Diabetes; 2003 Jun; 52(6):1409-16. PubMed ID: 12765951
    [Abstract] [Full Text] [Related]

  • 2. Increased glucocorticoid receptor and 11{beta}-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db/db mice.
    Liu Y, Nakagawa Y, Wang Y, Sakurai R, Tripathi PV, Lutfy K, Friedman TC.
    Diabetes; 2005 Jan; 54(1):32-40. PubMed ID: 15616008
    [Abstract] [Full Text] [Related]

  • 3. Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice.
    Liu Y, Nakagawa Y, Wang Y, Liu L, Du H, Wang W, Ren X, Lutfy K, Friedman TC.
    J Mol Endocrinol; 2008 Aug; 41(2):53-64. PubMed ID: 18524870
    [Abstract] [Full Text] [Related]

  • 4. Regulation of 11beta-hydroxysteroid dehydrogenase type 1 and glucose-stimulated insulin secretion in pancreatic islets of Langerhans.
    Ortsäter H, Alberts P, Warpman U, Engblom LO, Abrahmsén L, Bergsten P.
    Diabetes Metab Res Rev; 2005 Aug; 21(4):359-66. PubMed ID: 15586384
    [Abstract] [Full Text] [Related]

  • 5. In obese mice, exercise training increases 11β-HSD1 expression, contributing to glucocorticoid activation and suppression of pulmonary inflammation.
    Du SF, Yu Q, Chuan K, Ye CL, He ZJ, Liu SJ, Zhu XY, Liu YJ.
    J Appl Physiol (1985); 2017 Oct 01; 123(4):717-727. PubMed ID: 28663379
    [Abstract] [Full Text] [Related]

  • 6. MRNA and enzyme activity of hepatic 11beta-hydroxysteroid dehydrogenase type 1 are elevated in C57BL/KsJ-db/db mice.
    Aoki K, Homma M, Hirano T, Oka K, Satoh S, Mukasa K, Ito S, Sekihara H.
    Life Sci; 2001 Oct 12; 69(21):2543-9. PubMed ID: 11693261
    [Abstract] [Full Text] [Related]

  • 7. Overexpression of 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue and portal hypercortisolism in non-alcoholic fatty liver disease.
    Candia R, Riquelme A, Baudrand R, Carvajal CA, Morales M, Solís N, Pizarro M, Escalona A, Carrasco G, Boza C, Pérez G, Padilla O, Cerda J, Fardella CE, Arrese M.
    Liver Int; 2012 Mar 12; 32(3):392-9. PubMed ID: 22136330
    [Abstract] [Full Text] [Related]

  • 8. The 11β-hydroxysteroid dehydrogenase type 1 inhibitor protects against the insulin resistance and hepatic steatosis in db/db mice.
    Yuan X, Li H, Bai H, Zhao X, Zhang C, Liu H, Zhang Y, Zhao B, Wu Y, Liu J, Xiang Q, Feng B, Chu Y, Huang Y.
    Eur J Pharmacol; 2016 Oct 05; 788():140-151. PubMed ID: 27242185
    [Abstract] [Full Text] [Related]

  • 9. 11-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice.
    Harno E, Cottrell EC, Keevil BG, DeSchoolmeester J, Bohlooly-Y M, Andersén H, Turnbull AV, Leighton B, White A.
    Endocrinology; 2013 Oct 05; 154(10):3599-609. PubMed ID: 23832962
    [Abstract] [Full Text] [Related]

  • 10. Vitamin A decreases pre-receptor amplification of glucocorticoids in obesity: study on the effect of vitamin A on 11beta-hydroxysteroid dehydrogenase type 1 activity in liver and visceral fat of WNIN/Ob obese rats.
    Sakamuri VP, Ananthathmakula P, Veettil GN, Ayyalasomayajula V.
    Nutr J; 2011 Jun 23; 10():70. PubMed ID: 21696642
    [Abstract] [Full Text] [Related]

  • 11. 11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.
    Pereira CD, Azevedo I, Monteiro R, Martins MJ.
    Diabetes Obes Metab; 2012 Oct 23; 14(10):869-81. PubMed ID: 22321826
    [Abstract] [Full Text] [Related]

  • 12. Tissue-specific dysregulation of hexose-6-phosphate dehydrogenase and glucose-6-phosphate transporter production in db/db mice as a model of type 2 diabetes.
    Wang Y, Nakagawa Y, Liu L, Wang W, Ren X, Anghel A, Lutfy K, Friedman TC, Liu Y.
    Diabetologia; 2011 Feb 23; 54(2):440-50. PubMed ID: 21052977
    [Abstract] [Full Text] [Related]

  • 13. Carbenoxolone treatment ameliorated metabolic syndrome in WNIN/Ob obese rats, but induced severe fat loss and glucose intolerance in lean rats.
    Prasad Sakamuri SS, Sukapaka M, Prathipati VK, Nemani H, Putcha UK, Pothana S, Koppala SR, Ponday LR, Acharya V, Veetill GN, Ayyalasomayajula V.
    PLoS One; 2012 Feb 23; 7(12):e50216. PubMed ID: 23284633
    [Abstract] [Full Text] [Related]

  • 14. Specific reduction of G6PT may contribute to downregulation of hepatic 11β-HSD1 in diabetic mice.
    Du H, Liu L, Wang Y, Nakagawa Y, Lyzlov A, Lutfy K, Friedman TC, Peng X, Liu Y.
    J Mol Endocrinol; 2013 Apr 23; 50(2):167-78. PubMed ID: 23267038
    [Abstract] [Full Text] [Related]

  • 15. Feeding Obese Diabetic Mice a Genistein Diet Induces Thermogenic and Metabolic Change.
    Rockwood S, Broderick TL, Al-Nakkash L.
    J Med Food; 2018 Apr 23; 21(4):332-339. PubMed ID: 29261006
    [Abstract] [Full Text] [Related]

  • 16. Different responsiveness in body weight and hepatic 11beta-hydroxysteroid dehydrogenase (11beta-HSD) type 1 mrna to 11beta-HSD inhibition by glycyrrhetinic acid treatment in obese and lean zucker rats.
    Li RS, Nakagawa Y, Nakanishi T, Fujisawa Y, Ohzeki T.
    Metabolism; 2004 May 23; 53(5):600-6. PubMed ID: 15131764
    [Abstract] [Full Text] [Related]

  • 17. Is 11beta-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of carbenoxolone in lean and obese Zucker rats.
    Livingstone DE, Walker BR.
    J Pharmacol Exp Ther; 2003 Apr 23; 305(1):167-72. PubMed ID: 12649365
    [Abstract] [Full Text] [Related]

  • 18. Pharmacological evaluation of adipose dysfunction via 11β-hydroxysteroid dehydrogenase type 1 in the development of diabetes in diet-induced obese mice with cortisone pellet implantation.
    Akiyama N, Akiyama Y, Kato H, Kuroda T, Ono T, Imagawa K, Asakura K, Shinosaki T, Murayama T, Hanasaki K.
    J Pharmacol Exp Ther; 2014 Apr 23; 349(1):66-74. PubMed ID: 24511146
    [Abstract] [Full Text] [Related]

  • 19. Emodin, an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, regulates adipocyte function in vitro and exerts anti-diabetic effect in ob/ob mice.
    Wang YJ, Huang SL, Feng Y, Ning MM, Leng Y.
    Acta Pharmacol Sin; 2012 Sep 23; 33(9):1195-203. PubMed ID: 22922341
    [Abstract] [Full Text] [Related]

  • 20. Dysregulation of glucocorticoid metabolism in murine obesity: comparable effects of leptin resistance and deficiency.
    Livingstone DE, Grassick SL, Currie GL, Walker BR, Andrew R.
    J Endocrinol; 2009 May 23; 201(2):211-8. PubMed ID: 19223399
    [Abstract] [Full Text] [Related]

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