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198 related items for PubMed ID: 12769745
21. 1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies. Tsirkone VG, Tsoukala E, Lamprakis C, Manta S, Hayes JM, Skamnaki VT, Drakou C, Zographos SE, Komiotis D, Leonidas DD. Bioorg Med Chem; 2010 May 15; 18(10):3413-25. PubMed ID: 20430629 [Abstract] [Full Text] [Related]
22. New inhibitors of glycogen phosphorylase as potential antidiabetic agents. Somsák L, Czifrák K, Tóth M, Bokor E, Chrysina ED, Alexacou KM, Hayes JM, Tiraidis C, Lazoura E, Leonidas DD, Zographos SE, Oikonomakos NG. Curr Med Chem; 2008 May 15; 15(28):2933-83. PubMed ID: 19075645 [Abstract] [Full Text] [Related]
23. Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase. Kantsadi AL, Bokor É, Kun S, Stravodimos GA, Chatzileontiadou DSM, Leonidas DD, Juhász-Tóth É, Szakács A, Batta G, Docsa T, Gergely P, Somsák L. Eur J Med Chem; 2016 Nov 10; 123():737-745. PubMed ID: 27522507 [Abstract] [Full Text] [Related]
24. Glycogen phosphorylase inhibitors: a free energy perturbation analysis of glucopyranose spirohydantoin analogues. Archontis G, Watson KA, Xie Q, Andreou G, Chrysina ED, Zographos SE, Oikonomakos NG, Karplus M. Proteins; 2005 Dec 01; 61(4):984-98. PubMed ID: 16245298 [Abstract] [Full Text] [Related]
27. Synthesis, enzyme kinetics and computational evaluation of N-(β-D-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors. Polyák M, Varga G, Szilágyi B, Juhász L, Docsa T, Gergely P, Begum J, Hayes JM, Somsák L. Bioorg Med Chem; 2013 Sep 15; 21(18):5738-47. PubMed ID: 23938052 [Abstract] [Full Text] [Related]
28. Glycogen phosphorylase inhibitor N-(3,5-dimethyl-Benzoyl)-N'-(β-D-glucopyranosyl)urea improves glucose tolerance under normoglycemic and diabetic conditions and rearranges hepatic metabolism. Nagy L, Docsa T, Szántó M, Brunyánszki A, Hegedűs C, Márton J, Kónya B, Virág L, Somsák L, Gergely P, Bai P. PLoS One; 2013 Sep 15; 8(7):e69420. PubMed ID: 23936011 [Abstract] [Full Text] [Related]
29. Design and Synthesis of 3-(β-d-Glucopyranosyl)-4-amino/4-guanidino Pyrazole Derivatives and Analysis of Their Glycogen Phosphorylase Inhibitory Potential. Kun S, Mathomes RT, Docsa T, Somsák L, Hayes JM. Molecules; 2023 Mar 28; 28(7):. PubMed ID: 37049768 [Abstract] [Full Text] [Related]
30. Recent advances in the allosteric inhibition of glycogen phosphorylase. Loughlin WA. Mini Rev Med Chem; 2010 Oct 28; 10(12):1139-55. PubMed ID: 20716052 [Abstract] [Full Text] [Related]
31. Synthesis of C-xylopyranosyl- and xylopyranosylidene-spiro-heterocycles as potential inhibitors of glycogen phosphorylase. Somsák L, Bokor É, Czibere B, Czifrák K, Koppány C, Kulcsár L, Kun S, Szilágyi E, Tóth M, Docsa T, Gergely P. Carbohydr Res; 2014 Nov 18; 399():38-48. PubMed ID: 25081322 [Abstract] [Full Text] [Related]
32. Dual-Target Compounds against Type 2 Diabetes Mellitus: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors. Sipos Á, Szennyes E, Hajnal NÉ, Kun S, Szabó KE, Uray K, Somsák L, Docsa T, Bokor É. Pharmaceuticals (Basel); 2021 Apr 15; 14(4):. PubMed ID: 33920838 [Abstract] [Full Text] [Related]
33. Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase. Anagnostou E, Kosmopoulou MN, Chrysina ED, Leonidas DD, Hadjiloi T, Tiraidis C, Zographos SE, Györgydeák Z, Somsák L, Docsa T, Gergely P, Kolisis FN, Oikonomakos NG. Bioorg Med Chem; 2006 Jan 01; 14(1):181-9. PubMed ID: 16213146 [Abstract] [Full Text] [Related]
34. Combined in silico and in vitro studies to identify novel antidiabetic flavonoids targeting glycogen phosphorylase. Brás NF, Neves RPP, Lopes FAA, Correia MAS, Palma AS, Sousa SF, Ramos MJ. Bioorg Chem; 2021 Mar 01; 108():104552. PubMed ID: 33357981 [Abstract] [Full Text] [Related]
35. Synthesis and biological evaluation of asiatic acid derivatives as inhibitors of glycogen phosphorylases. Zhang L, Chen J, Gong Y, Liu J, Zhang L, Hua W, Sun H. Chem Biodivers; 2009 Jun 01; 6(6):864-74. PubMed ID: 19551727 [Abstract] [Full Text] [Related]
36. Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Kyriakis E, Solovou TGA, Kun S, Czifrák K, Szőcs B, Juhász L, Bokor É, Stravodimos GA, Kantsadi AL, Chatzileontiadou DSM, Skamnaki VT, Somsák L, Leonidas DD. Bioorg Chem; 2018 Apr 01; 77():485-493. PubMed ID: 29454281 [Abstract] [Full Text] [Related]