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340 related items for PubMed ID: 12774017

  • 1. Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development.
    Kamiya A, Inoue Y, Gonzalez FJ.
    Hepatology; 2003 Jun; 37(6):1375-84. PubMed ID: 12774017
    [Abstract] [Full Text] [Related]

  • 2. Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis.
    Hayhurst GP, Lee YH, Lambert G, Ward JM, Gonzalez FJ.
    Mol Cell Biol; 2001 Feb; 21(4):1393-403. PubMed ID: 11158324
    [Abstract] [Full Text] [Related]

  • 3. TNF-alpha regulates mouse fetal hepatic maturation induced by oncostatin M and extracellular matrices.
    Kamiya A, Gonzalez FJ.
    Hepatology; 2004 Sep; 40(3):527-36. PubMed ID: 15349890
    [Abstract] [Full Text] [Related]

  • 4. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
    Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB.
    Nat Med; 2003 Feb; 9(2):220-4. PubMed ID: 12514743
    [Abstract] [Full Text] [Related]

  • 5. Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus-mediated antisense targeting.
    Jover R, Bort R, Gómez-Lechón MJ, Castell JV.
    Hepatology; 2001 Mar; 33(3):668-75. PubMed ID: 11230748
    [Abstract] [Full Text] [Related]

  • 6. Transcriptional regulation of the PXR gene: identification and characterization of a functional peroxisome proliferator-activated receptor alpha binding site within the proximal promoter of PXR.
    Aouabdi S, Gibson G, Plant N.
    Drug Metab Dispos; 2006 Jan; 34(1):138-44. PubMed ID: 16243957
    [Abstract] [Full Text] [Related]

  • 7. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
    Ferguson SS, Chen Y, LeCluyse EL, Negishi M, Goldstein JA.
    Mol Pharmacol; 2005 Sep; 68(3):747-57. PubMed ID: 15933212
    [Abstract] [Full Text] [Related]

  • 8. Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.
    Li J, Ning G, Duncan SA.
    Genes Dev; 2000 Feb 15; 14(4):464-74. PubMed ID: 10691738
    [Abstract] [Full Text] [Related]

  • 9. Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis.
    Parviz F, Matullo C, Garrison WD, Savatski L, Adamson JW, Ning G, Kaestner KH, Rossi JM, Zaret KS, Duncan SA.
    Nat Genet; 2003 Jul 15; 34(3):292-6. PubMed ID: 12808453
    [Abstract] [Full Text] [Related]

  • 10. Activation of glucokinase gene expression by hepatic nuclear factor 4alpha in primary hepatocytes.
    Roth U, Jungermann K, Kietzmann T.
    Biochem J; 2002 Jul 01; 365(Pt 1):223-8. PubMed ID: 11950391
    [Abstract] [Full Text] [Related]

  • 11. Hepatocyte nuclear factors 1alpha and 4alpha control expression of proline oxidase in adult liver.
    Kamiya A, Inoue Y, Kodama T, Gonzalez FJ.
    FEBS Lett; 2004 Dec 03; 578(1-2):63-8. PubMed ID: 15581617
    [Abstract] [Full Text] [Related]

  • 12. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase.
    Echchgadda I, Song CS, Oh T, Ahmed M, De La Cruz IJ, Chatterjee B.
    Mol Endocrinol; 2007 Sep 03; 21(9):2099-111. PubMed ID: 17595319
    [Abstract] [Full Text] [Related]

  • 13. Growth hormone regulates the expression of hepatocyte nuclear factor-3 gamma and other liver-enriched transcription factors in the bovine liver.
    Eleswarapu S, Jiang H.
    J Endocrinol; 2005 Jan 03; 184(1):95-105. PubMed ID: 15642787
    [Abstract] [Full Text] [Related]

  • 14. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
    Roth A, Looser R, Kaufmann M, Blättler SM, Rencurel F, Huang W, Moore DD, Meyer UA.
    Mol Pharmacol; 2008 Apr 03; 73(4):1282-9. PubMed ID: 18187584
    [Abstract] [Full Text] [Related]

  • 15. Characterization of glucocorticoid receptor and hepatocyte nuclear factor 4alpha (HNF4alpha) binding to the hnf4alpha gene in the liver.
    Bailly A, Briançon N, Weiss MC.
    Biochimie; 2009 Sep 03; 91(9):1095-103. PubMed ID: 19540905
    [Abstract] [Full Text] [Related]

  • 16. The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter.
    Chen Y, Kissling G, Negishi M, Goldstein JA.
    J Pharmacol Exp Ther; 2005 Sep 03; 314(3):1125-33. PubMed ID: 15919766
    [Abstract] [Full Text] [Related]

  • 17. Adenovirus-mediated hepatocyte nuclear factor-4alpha overexpression maintains liver phenotype in cultured rat hepatocytes.
    Naiki T, Nagaki M, Asano T, Kimata T, Moriwaki H.
    Biochem Biophys Res Commun; 2005 Sep 23; 335(2):496-500. PubMed ID: 16087161
    [Abstract] [Full Text] [Related]

  • 18. Nuclear receptor expression in fetal and pediatric liver: correlation with CYP3A expression.
    Vyhlidal CA, Gaedigk R, Leeder JS.
    Drug Metab Dispos; 2006 Jan 23; 34(1):131-7. PubMed ID: 16243958
    [Abstract] [Full Text] [Related]

  • 19. Expression of Wilms' tumor suppressor in the liver with cirrhosis: relation to hepatocyte nuclear factor 4 and hepatocellular function.
    Berasain C, Herrero JI, García-Trevijano ER, Avila MA, Esteban JI, Mato JM, Prieto J.
    Hepatology; 2003 Jul 23; 38(1):148-57. PubMed ID: 12829997
    [Abstract] [Full Text] [Related]

  • 20. Perinatal lipopolysaccharide exposure downregulates pregnane X receptor and Cyp3a11 expression in fetal mouse liver.
    Xu DX, Chen YH, Wang JP, Sun MF, Wang H, Wei LZ, Wei W.
    Toxicol Sci; 2005 Sep 23; 87(1):38-45. PubMed ID: 15976188
    [Abstract] [Full Text] [Related]

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