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Journal Abstract Search

331 related items for PubMed ID: 12776987

  • 1.
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  • 2. GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase.
    Annerén C, Reedquist KA, Bos JL, Welsh M.
    J Biol Chem; 2000 Sep 15; 275(37):29153-61. PubMed ID: 10878015
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  • 4. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
    Welsh N, Makeeva N, Welsh M.
    Mol Med; 2002 Nov 15; 8(11):695-704. PubMed ID: 12520086
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  • 5. The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells.
    Holmqvist K, Cross M, Riley D, Welsh M.
    Cell Signal; 2003 Feb 15; 15(2):171-9. PubMed ID: 12464388
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  • 6. The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.
    Cross MJ, Lu L, Magnusson P, Nyqvist D, Holmqvist K, Welsh M, Claesson-Welsh L.
    Mol Biol Cell; 2002 Aug 15; 13(8):2881-93. PubMed ID: 12181353
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  • 9. Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins.
    Karlsson T, Songyang Z, Landgren E, Lavergne C, Di Fiore PP, Anafi M, Pawson T, Cantley LC, Claesson-Welsh L, Welsh M.
    Oncogene; 1995 Apr 20; 10(8):1475-83. PubMed ID: 7537362
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  • 10. The SHB adapter protein is required for efficient multilineage differentiation of mouse embryonic stem cells.
    Kriz V, Annerén C, Lai C, Karlsson J, Mares J, Welsh M.
    Exp Cell Res; 2003 May 15; 286(1):40-56. PubMed ID: 12729793
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  • 11. Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells.
    Lindholm CK, Henriksson ML, Hallberg B, Welsh M.
    Eur J Biochem; 2002 Jul 15; 269(13):3279-88. PubMed ID: 12084069
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  • 12. Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization.
    Hooshmand-Rad R, Lu L, Heldin CH, Claesson-Welsh L, Welsh M.
    Exp Cell Res; 2000 Jun 15; 257(2):245-54. PubMed ID: 10837138
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  • 13. The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.
    Holmqvist K, Cross MJ, Rolny C, Hägerkvist R, Rahimi N, Matsumoto T, Claesson-Welsh L, Welsh M.
    J Biol Chem; 2004 May 21; 279(21):22267-75. PubMed ID: 15026417
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  • 14. NGF-Dependent neurite outgrowth in PC12 cells overexpressing the Src homology 2-domain protein shb requires activation of the Rap1 pathway.
    Lu L, Annerén C, Reedquist KA, Bos JL, Welsh M.
    Exp Cell Res; 2000 Sep 15; 259(2):370-7. PubMed ID: 10964504
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  • 15. Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells.
    Lindholm CK, Gylfe E, Zhang W, Samelson LE, Welsh M.
    J Biol Chem; 1999 Sep 24; 274(39):28050-7. PubMed ID: 10488157
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  • 16. Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb.
    Funa NS, Saldeen J, Akerblom B, Welsh M.
    Differentiation; 2008 May 24; 76(5):443-53. PubMed ID: 18093225
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  • 17. Shb is a ubiquitously expressed Src homology 2 protein.
    Welsh M, Mares J, Karlsson T, Lavergne C, Bréant B, Claesson-Welsh L.
    Oncogene; 1994 Jan 24; 9(1):19-27. PubMed ID: 8302579
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  • 20. The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity.
    Welsh M, Welsh C, Ekman M, Dixelius J, Hägerkvist R, Annerén C, Akerblom B, Mahboobi S, Chandrasekharan S, Liu ET.
    Biochem J; 2004 Aug 15; 382(Pt 1):261-8. PubMed ID: 15186217
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