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Pubmed for Handhelds

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Journal Abstract Search

898 related items for PubMed ID: 12778055

  • 1. Development of potent monoclonal antibody auristatin conjugates for cancer therapy.
    Doronina SO, Toki BE, Torgov MY, Mendelsohn BA, Cerveny CG, Chace DF, DeBlanc RL, Gearing RP, Bovee TD, Siegall CB, Francisco JA, Wahl AF, Meyer DL, Senter PD.
    Nat Biotechnol; 2003 Jul; 21(7):778-84. PubMed ID: 12778055
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  • 2. Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity.
    Doronina SO, Mendelsohn BA, Bovee TD, Cerveny CG, Alley SC, Meyer DL, Oflazoglu E, Toki BE, Sanderson RJ, Zabinski RF, Wahl AF, Senter PD.
    Bioconjug Chem; 2006 Jul; 17(1):114-24. PubMed ID: 16417259
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  • 3. In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate.
    Sanderson RJ, Hering MA, James SF, Sun MM, Doronina SO, Siadak AW, Senter PD, Wahl AF.
    Clin Cancer Res; 2005 Jan 15; 11(2 Pt 1):843-52. PubMed ID: 15701875
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  • 4. Secondary mAb--vcMMAE conjugates are highly sensitive reporters of antibody internalization via the lysosome pathway.
    Klussman K, Mixan BJ, Cerveny CG, Meyer DL, Senter PD, Wahl AF.
    Bioconjug Chem; 2004 Jan 15; 15(4):765-73. PubMed ID: 15264863
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  • 5. Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate.
    Hamblett KJ, Senter PD, Chace DF, Sun MM, Lenox J, Cerveny CG, Kissler KM, Bernhardt SX, Kopcha AK, Zabinski RF, Meyer DL, Francisco JA.
    Clin Cancer Res; 2004 Oct 15; 10(20):7063-70. PubMed ID: 15501986
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  • 9. Targeted cancer therapy: conferring specificity to cytotoxic drugs.
    Chari RV.
    Acc Chem Res; 2008 Jan 15; 41(1):98-107. PubMed ID: 17705444
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  • 13. Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates.
    Law CL, Cerveny CG, Gordon KA, Klussman K, Mixan BJ, Chace DF, Meyer DL, Doronina SO, Siegall CB, Francisco JA, Senter PD, Wahl AF.
    Clin Cancer Res; 2004 Dec 01; 10(23):7842-51. PubMed ID: 15585616
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  • 15. Design, synthesis, and in vitro evaluation of dipeptide-based antibody minor groove binder conjugates.
    Jeffrey SC, Torgov MY, Andreyka JB, Boddington L, Cerveny CG, Denny WA, Gordon KA, Gustin D, Haugen J, Kline T, Nguyen MT, Senter PD.
    J Med Chem; 2005 Mar 10; 48(5):1344-58. PubMed ID: 15743178
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  • 16. Antibody-cytotoxic agent conjugates for cancer therapy.
    Chen J, Jaracz S, Zhao X, Chen S, Ojima I.
    Expert Opin Drug Deliv; 2005 Sep 10; 2(5):873-90. PubMed ID: 16296784
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  • 17. Design, synthesis, and biological evaluation of antibody-drug conjugates comprised of potent camptothecin analogues.
    Burke PJ, Senter PD, Meyer DW, Miyamoto JB, Anderson M, Toki BE, Manikumar G, Wani MC, Kroll DJ, Jeffrey SC.
    Bioconjug Chem; 2009 Jun 10; 20(6):1242-50. PubMed ID: 19469529
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  • 20. Preparation, phototoxicity and biodistribution studies of anti-carcinoembryonic antigen monoclonal antibody-phthalocyanine conjugates.
    Carcenac M, Larroque C, Langlois R, van Lier JE, Artus JC, Pèlegrin A.
    Photochem Photobiol; 1999 Dec 10; 70(6):930-6. PubMed ID: 10628305
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