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163 related items for PubMed ID: 12790537

  • 1. Synthetic studies on ecteinascidin-743: constructing a versatile pentacyclic intermediate for the synthesis of ecteinascidins and saframycins.
    Jin W, Metobo S, Williams RM.
    Org Lett; 2003 Jun 12; 5(12):2095-8. PubMed ID: 12790537
    [Abstract] [Full Text] [Related]

  • 2. Enantioselective synthesis of saframycin A and evaluation of antitumor activity relative to ecteinascidin/saframycin hybrids.
    Martinez EJ, Corey EJ.
    Org Lett; 1999 Jul 15; 1(1):75-7. PubMed ID: 10822537
    [Abstract] [Full Text] [Related]

  • 3. Synthesis of ecteinascidin ET-743 and phthalascidin Pt-650 from cyanosafracin B.
    Cuevas C, Pérez M, Martín MJ, Chicharro JL, Fernández-Rivas C, Flores M, Francesch A, Gallego P, Zarzuelo M, de La Calle F, García J, Polanco C, Rodríguez I, Manzanares I.
    Org Lett; 2000 Aug 10; 2(16):2545-8. PubMed ID: 10956543
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and cytotoxic evaluation of some cribrostatin-ecteinascidin analogues.
    Wright BJ, Chan C, Danishefsky SJ.
    J Nat Prod; 2008 Mar 10; 71(3):409-14. PubMed ID: 18278868
    [Abstract] [Full Text] [Related]

  • 5. Total synthesis of ecteinascidin 743.
    Chen J, Chen X, Bois-Choussy M, Zhu J.
    J Am Chem Soc; 2006 Jan 11; 128(1):87-9. PubMed ID: 16390134
    [Abstract] [Full Text] [Related]

  • 6. The potent anticancer compound ecteinascidin-743 (ET-743) as its 2-propanol disolvate.
    Sainz-Diaz CI, Manzanares I, Francesch A, Garcia-Ruiz J.
    Acta Crystallogr C; 2003 Apr 11; 59(Pt 4):O197-8. PubMed ID: 12682407
    [Abstract] [Full Text] [Related]

  • 7. Studies directed to the total synthesis of ET 743 and analogues thereof: an expeditious route to the ABFGH subunit.
    Zhou B, Guo J, Danishefsky SJ.
    Org Lett; 2002 Jan 10; 4(1):43-6. PubMed ID: 11772086
    [Abstract] [Full Text] [Related]

  • 8. Stereospecific formal total synthesis of ecteinascidin 743.
    Zheng S, Chan C, Furuuchi T, Wright BJ, Zhou B, Guo J, Danishefsky SJ.
    Angew Chem Int Ed Engl; 2006 Mar 03; 45(11):1754-9. PubMed ID: 16496274
    [No Abstract] [Full Text] [Related]

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  • 10. A practical synthesis of the ABC ring model of ecteinascidins.
    Saito N, Tachi M, Seki R, Kamayachi H, Kubo A.
    Chem Pharm Bull (Tokyo); 2000 Oct 03; 48(10):1549-57. PubMed ID: 11045468
    [Abstract] [Full Text] [Related]

  • 11. Synthetic studies toward ecteinascidin 743.
    Chen X, Chen J, De Paolis M, Zhu J.
    J Org Chem; 2005 May 27; 70(11):4397-408. PubMed ID: 15903318
    [Abstract] [Full Text] [Related]

  • 12. Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove.
    Zewail-Foote M, Hurley LH.
    J Med Chem; 1999 Jul 15; 42(14):2493-7. PubMed ID: 10411470
    [Abstract] [Full Text] [Related]

  • 13. A new, more efficient, and effective process for the synthesis of a key pentacyclic intermediate for production of ecteinascidin and phthalascidin antitumor agents.
    Martinez EJ, Corey EJ.
    Org Lett; 2000 Apr 06; 2(7):993-6. PubMed ID: 10768205
    [Abstract] [Full Text] [Related]

  • 14. Development of Yondelis (trabectedin, ET-743). A semisynthetic process solves the supply problem.
    Cuevas C, Francesch A.
    Nat Prod Rep; 2009 Mar 06; 26(3):322-37. PubMed ID: 19240944
    [Abstract] [Full Text] [Related]

  • 15. Ecteinascidins. A review of the chemistry, biology and clinical utility of potent tetrahydroisoquinoline antitumor antibiotics.
    Le VH, Inai M, Williams RM, Kan T.
    Nat Prod Rep; 2015 Feb 06; 32(2):328-47. PubMed ID: 25273374
    [Abstract] [Full Text] [Related]

  • 16. DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata.
    Pommier Y, Kohlhagen G, Bailly C, Waring M, Mazumder A, Kohn KW.
    Biochemistry; 1996 Oct 15; 35(41):13303-9. PubMed ID: 8873596
    [Abstract] [Full Text] [Related]

  • 17. Synthetic studies on Et-743. Assembly of the pentacyclic core and a formal total synthesis.
    Fishlock D, Williams RM.
    J Org Chem; 2008 Dec 19; 73(24):9594-600. PubMed ID: 18687003
    [Abstract] [Full Text] [Related]

  • 18. Increased DNA binding specificity for antitumor ecteinascidin 743 through protein-DNA interactions?
    García-Nieto R, Manzanares I, Cuevas C, Gago F.
    J Med Chem; 2000 Nov 16; 43(23):4367-9. PubMed ID: 11087561
    [No Abstract] [Full Text] [Related]

  • 19. Trabectedin: ET 743, ecteinascidin 743, Yondelis.
    Drugs R D; 2003 Nov 16; 4(1):75-81. PubMed ID: 12568645
    [No Abstract] [Full Text] [Related]

  • 20. Further insight into the DNA recognition mechanism of trabectedin from the differential affinity of its demethylated analogue ecteinascidin ET729 for the triplet DNA binding site CGA.
    Marco E, David-Cordonnier MH, Bailly C, Cuevas C, Gago F.
    J Med Chem; 2006 Nov 16; 49(23):6925-9. PubMed ID: 17154523
    [Abstract] [Full Text] [Related]

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