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170 related items for PubMed ID: 12790579
21. Expedient solid-phase synthesis of both symmetric and asymmetric diol libraries targeting aspartic proteases. Shi H, Liu K, Leong WW, Yao SQ. Bioorg Med Chem Lett; 2009 Jul 15; 19(14):3945-8. PubMed ID: 19328682 [Abstract] [Full Text] [Related]
22. On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 A resolution. Dusková J, Dohnálek J, Skálová T, Petroková H, Vondrácková E, Hradílek M, Konvalinka J, Soucek M, Brynda J, Fábry M, Sedlácek J, Hasek J. Acta Crystallogr D Biol Crystallogr; 2006 May 15; 62(Pt 5):489-97. PubMed ID: 16627941 [Abstract] [Full Text] [Related]
23. Stereoselective synthesis of (Z)-alkene-containing proline dipeptide mimetics. Sasaki Y, Niida A, Tsuji T, Shigenaga A, Fujii N, Otaka A. J Org Chem; 2006 Jun 23; 71(13):4969-79. PubMed ID: 16776529 [Abstract] [Full Text] [Related]
24. Design of inhibitors against HIV, HTLV-I, and Plasmodium falciparum aspartic proteases. Abdel-Rahman HM, Kimura T, Hidaka K, Kiso A, Nezami A, Freire E, Hayashi Y, Kiso Y. Biol Chem; 2004 Nov 23; 385(11):1035-9. PubMed ID: 15576323 [Abstract] [Full Text] [Related]
25. Design of potent aspartic protease inhibitors to treat various diseases. Nguyen JT, Hamada Y, Kimura T, Kiso Y. Arch Pharm (Weinheim); 2008 Sep 23; 341(9):523-35. PubMed ID: 18763714 [Abstract] [Full Text] [Related]
26. Novel cyclourethane-derived HIV protease inhibitors: a ring-closing olefin metathesis based strategy. Ghosh AK, Swanson LM, Liu C, Hussain KA, Cho H, Walters DE, Holland L, Buthod J. Bioorg Med Chem Lett; 2002 Aug 05; 12(15):1993-6. PubMed ID: 12113826 [Abstract] [Full Text] [Related]
29. Synthesis of potent beta-secretase inhibitors containing a hydroxyethylamine dipeptide isostere and their structure-activity relationship studies. Tamamura H, Kato T, Otaka A, Fujii N. Org Biomol Chem; 2003 Jul 21; 1(14):2468-73. PubMed ID: 12956063 [Abstract] [Full Text] [Related]
30. The Effects of Side-Chain Configurations of a Retro-Inverso-Type Inhibitor on the Human T-Cell Leukemia Virus (HTLV)-1 Protease. Awahara C, Oku D, Furuta S, Kobayashi K, Teruya K, Akaji K, Hattori Y. Molecules; 2022 Mar 02; 27(5):. PubMed ID: 35268749 [Abstract] [Full Text] [Related]
31. Achiral oligoamines as versatile tool for the development of aspartic protease inhibitors. Blum A, Böttcher J, Sammet B, Luksch T, Heine A, Klebe G, Diederich WE. Bioorg Med Chem; 2008 Sep 15; 16(18):8574-86. PubMed ID: 18760609 [Abstract] [Full Text] [Related]
33. A novel dipeptide-based HIV protease inhibitor containing allophenylnorstatine. Abdel-Rahman HM, el-Koussi NA, Alkaramany GS, Youssef AF, Kiso Y. Arch Pharm (Weinheim); 2004 Nov 15; 337(11):587-98. PubMed ID: 15540219 [Abstract] [Full Text] [Related]
34. Synthesis and activity of tetrapeptidic HTLV-I protease inhibitors possessing different P3-cap moieties. Zhang M, Nguyen JT, Kumada HO, Kimura T, Cheng M, Hayashi Y, Kiso Y. Bioorg Med Chem; 2008 May 15; 16(10):5795-802. PubMed ID: 18400502 [Abstract] [Full Text] [Related]
35. Lysine sulfonamides as novel HIV-protease inhibitors: Nepsilon-disubstituted ureas. Stranix BR, Sauvé G, Bouzide A, Coté A, Sévigny G, Yelle J, Perron V. Bioorg Med Chem Lett; 2004 Aug 02; 14(15):3971-4. PubMed ID: 15225709 [Abstract] [Full Text] [Related]
36. Effect of prime-site sequence of retro-inverso-modified HTLV-1 protease inhibitor. Awahara C, Tatsumi T, Furuta S, Shinjoh G, Konno H, Nosaka K, Kobayashi K, Hattori Y, Akaji K. Bioorg Med Chem; 2014 Apr 15; 22(8):2482-8. PubMed ID: 24680060 [Abstract] [Full Text] [Related]
37. Alpha-ketoamide Phe-Pro isostere as a new core structure for the inhibition of HIV protease. Munoz B, Giam CZ, Wong CH. Bioorg Med Chem; 1994 Oct 15; 2(10):1085-90. PubMed ID: 7773625 [Abstract] [Full Text] [Related]
38. Amino-zinc-enolate carbometalation reactions: application to ring closure of terminally substituted olefin for the asymmetric synthesis of cis- and trans-3-prolinoleucine. Karoyan P, Quancard J, Vaissermann J, Chassaing G. J Org Chem; 2003 Mar 21; 68(6):2256-65. PubMed ID: 12636389 [Abstract] [Full Text] [Related]
39. Pentaerythrityltetramine scaffolds for solid-phase combinatorial chemistry. Virta P, Leppänen M, Lönnberg H. J Org Chem; 2004 Mar 19; 69(6):2008-16. PubMed ID: 15058947 [Abstract] [Full Text] [Related]
40. BACE-1 inhibitors part 1: identification of novel hydroxy ethylamines (HEAs). Clarke B, Demont E, Dingwall C, Dunsdon R, Faller A, Hawkins J, Hussain I, MacPherson D, Maile G, Matico R, Milner P, Mosley J, Naylor A, O'Brien A, Redshaw S, Riddell D, Rowland P, Soleil V, Smith KJ, Stanway S, Stemp G, Sweitzer S, Theobald P, Vesey D, Walter DS, Ward J, Wayne G. Bioorg Med Chem Lett; 2008 Feb 01; 18(3):1011-6. PubMed ID: 18171614 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]