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135 related items for PubMed ID: 12791699
1. An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells. Wang X, Khadpe J, Hu B, Iliakis G, Wang Y. J Biol Chem; 2003 Aug 15; 278(33):30869-74. PubMed ID: 12791699 [Abstract] [Full Text] [Related]
2. CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses. Yan T, Desai AB, Jacobberger JW, Sramkoski RM, Loh T, Kinsella TJ. Mol Cancer Ther; 2004 Sep 15; 3(9):1147-57. PubMed ID: 15367709 [Abstract] [Full Text] [Related]
3. Irradiation-induced G2/M checkpoint response requires ERK1/2 activation. Yan Y, Black CP, Cowan KH. Oncogene; 2007 Jul 12; 26(32):4689-98. PubMed ID: 17297454 [Abstract] [Full Text] [Related]
4. Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation. Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK. J Biol Chem; 2003 Apr 25; 278(17):14806-11. PubMed ID: 12588868 [Abstract] [Full Text] [Related]
5. Tachpyridine, a metal chelator, induces G2 cell-cycle arrest, activates checkpoint kinases, and sensitizes cells to ionizing radiation. Turner J, Koumenis C, Kute TE, Planalp RP, Brechbiel MW, Beardsley D, Cody B, Brown KD, Torti FM, Torti SV. Blood; 2005 Nov 01; 106(9):3191-9. PubMed ID: 16014567 [Abstract] [Full Text] [Related]
6. RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation. Yan Y, Greer PM, Cao PT, Kolb RH, Cowan KH. Breast Cancer Res; 2012 Apr 11; 14(2):R60. PubMed ID: 22494620 [Abstract] [Full Text] [Related]
7. Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive. Guo N, Faller DV, Vaziri C. Cell Growth Differ; 2002 Feb 11; 13(2):77-86. PubMed ID: 11864911 [Abstract] [Full Text] [Related]
8. Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chk1 pathway. Yamane K, Taylor K, Kinsella TJ. Biochem Biophys Res Commun; 2004 May 21; 318(1):297-302. PubMed ID: 15110787 [Abstract] [Full Text] [Related]
9. Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase. Stojic L, Mojas N, Cejka P, Di Pietro M, Ferrari S, Marra G, Jiricny J. Genes Dev; 2004 Jun 01; 18(11):1331-44. PubMed ID: 15175264 [Abstract] [Full Text] [Related]
10. Ku affects the CHK1-dependent G(2) checkpoint after ionizing radiation. Wang X, Li GC, Iliakis G, Wang Y. Cancer Res; 2002 Nov 01; 62(21):6031-4. PubMed ID: 12414624 [Abstract] [Full Text] [Related]
11. Three independent mechanisms for arrest in G2 after ionizing radiation. Landsverk KS, Patzke S, Rein ID, Stokke C, Lyng H, De Angelis PM, Stokke T. Cell Cycle; 2011 Mar 01; 10(5):819-29. PubMed ID: 21325885 [Abstract] [Full Text] [Related]
12. Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases. Cortez D. J Biol Chem; 2003 Sep 26; 278(39):37139-45. PubMed ID: 12847089 [Abstract] [Full Text] [Related]
13. DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells. Arlander SJ, Greene BT, Innes CL, Paules RS. Cancer Res; 2008 Jan 01; 68(1):89-97. PubMed ID: 18172300 [Abstract] [Full Text] [Related]
14. Ataxia-telangiectasia and Rad3-related and DNA-dependent protein kinase cooperate in G2 checkpoint activation by the DNA strand-breaking nucleoside analogue 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine. Liu X, Matsuda A, Plunkett W. Mol Cancer Ther; 2008 Jan 01; 7(1):133-42. PubMed ID: 18202016 [Abstract] [Full Text] [Related]
15. Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity. Walker M, Black EJ, Oehler V, Gillespie DA, Scott MT. Oncogene; 2009 Jun 18; 28(24):2314-23. PubMed ID: 19421147 [Abstract] [Full Text] [Related]
16. Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing. Feijoo C, Hall-Jackson C, Wu R, Jenkins D, Leitch J, Gilbert DM, Smythe C. J Cell Biol; 2001 Sep 03; 154(5):913-23. PubMed ID: 11535615 [Abstract] [Full Text] [Related]
17. Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway. Lee HJ, Hwang HI, Jang YJ. Cell Cycle; 2010 Jun 15; 9(12):2389-98. PubMed ID: 20581453 [Abstract] [Full Text] [Related]
18. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional. Lossaint G, Besnard E, Fisher D, Piette J, Dulić V. Oncogene; 2011 Oct 13; 30(41):4261-74. PubMed ID: 21532626 [Abstract] [Full Text] [Related]
19. Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage. Ha K, Fiskus W, Rao R, Balusu R, Venkannagari S, Nalabothula NR, Bhalla KN. Mol Cancer Ther; 2011 Jul 13; 10(7):1194-206. PubMed ID: 21566061 [Abstract] [Full Text] [Related]
20. Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Zhang X, Succi J, Feng Z, Prithivirajsingh S, Story MD, Legerski RJ. Mol Cell Biol; 2004 Oct 13; 24(20):9207-20. PubMed ID: 15456891 [Abstract] [Full Text] [Related] Page: [Next] [New Search]