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496 related items for PubMed ID: 12794826
1. In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes. Pelletier JP, Fernandes JC, Brunet J, Moldovan F, Schrier D, Flory C, Martel-Pelletier J. Arthritis Rheum; 2003 Jun; 48(6):1582-93. PubMed ID: 12794826 [Abstract] [Full Text] [Related]
2. Chondrocyte death in experimental osteoarthritis is mediated by MEK 1/2 and p38 pathways: role of cyclooxygenase-2 and inducible nitric oxide synthase. Pelletier JP, Fernandes JC, Jovanovic DV, Reboul P, Martel-Pelletier J. J Rheumatol; 2001 Nov; 28(11):2509-19. PubMed ID: 11708426 [Abstract] [Full Text] [Related]
7. [In vitro effect of alendronate on chondrocytes and articular cartilage and subchondral bone in rabbit anterior cruciate ligament transection model]. Hu H, Zhang L, Li B, Zhang Y, Liu X, Tian F, Cheng T, Wang Z. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2009 Dec; 23(12):1474-81. PubMed ID: 20073314 [Abstract] [Full Text] [Related]
8. Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes. Afif H, Benderdour M, Mfuna-Endam L, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Arthritis Res Ther; 2007 Dec; 9(2):R31. PubMed ID: 17386086 [Abstract] [Full Text] [Related]
9. Selective inhibition of inducible nitric oxide synthase reduces progression of experimental osteoarthritis in vivo: possible link with the reduction in chondrocyte apoptosis and caspase 3 level. Pelletier JP, Jovanovic DV, Lascau-Coman V, Fernandes JC, Manning PT, Connor JR, Currie MG, Martel-Pelletier J. Arthritis Rheum; 2000 Jun; 43(6):1290-9. PubMed ID: 10857787 [Abstract] [Full Text] [Related]
10. Esculetin (dihydroxycoumarin) inhibits the production of matrix metalloproteinases in cartilage explants, and oral administration of its prodrug, CPA-926, suppresses cartilage destruction in rabbit experimental osteoarthritis. Yamada H, Watanabe K, Saito T, Hayashi H, Niitani Y, Kikuchi T, Ito A, Fujikawa K, Lohmander LS. J Rheumatol; 1999 Mar; 26(3):654-62. PubMed ID: 10090178 [Abstract] [Full Text] [Related]
15. Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms. Thiel MJ, Schaefer CJ, Lesch ME, Mobley JL, Dudley DT, Tecle H, Barrett SD, Schrier DJ, Flory CM. Arthritis Rheum; 2007 Oct; 56(10):3347-57. PubMed ID: 17907188 [Abstract] [Full Text] [Related]
16. Hepatocyte growth factor induction of collagenase 3 production in human osteoarthritic cartilage: involvement of the stress-activated protein kinase/c-Jun N-terminal kinase pathway and a sensitive p38 mitogen-activated protein kinase inhibitor cascade. Reboul P, Pelletier JP, Tardif G, Benderdour M, Ranger P, Bottaro DP, Martel-Pelletier J. Arthritis Rheum; 2001 Jan; 44(1):73-84. PubMed ID: 11212179 [Abstract] [Full Text] [Related]
17. Intra-articular injection of the selective cyclooxygenase-2 inhibitor meloxicam (Mobic) reduces experimental osteoarthritis and nociception in rats. Wen ZH, Tang CC, Chang YC, Huang SY, Chen CH, Wu SC, Hsieh SP, Hsieh CS, Wang KY, Lin SY, Lee HL, Lee CH, Kuo HC, Chen WF, Jean YH. Osteoarthritis Cartilage; 2013 Dec; 21(12):1976-86. PubMed ID: 24084190 [Abstract] [Full Text] [Related]