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476 related items for PubMed ID: 12794826

  • 1. In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes.
    Pelletier JP, Fernandes JC, Brunet J, Moldovan F, Schrier D, Flory C, Martel-Pelletier J.
    Arthritis Rheum; 2003 Jun; 48(6):1582-93. PubMed ID: 12794826
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  • 4. Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase.
    Pelletier JP, Jovanovic D, Fernandes JC, Manning P, Connor JR, Currie MG, Di Battista JA, Martel-Pelletier J.
    Arthritis Rheum; 1998 Jul; 41(7):1275-86. PubMed ID: 9663486
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  • 5. Selective inhibition of inducible nitric oxide synthase in experimental osteoarthritis is associated with reduction in tissue levels of catabolic factors.
    Pelletier JP, Lascau-Coman V, Jovanovic D, Fernandes JC, Manning P, Connor JR, Currie MG, Martel-Pelletier J.
    J Rheumatol; 1999 Sep; 26(9):2002-14. PubMed ID: 10493683
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  • 6. Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis.
    Kobayashi T, Notoya K, Nakamura A, Akimoto K.
    Inflamm Res; 2005 Jun; 54(6):249-55. PubMed ID: 15973508
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  • 7. [In vitro effect of alendronate on chondrocytes and articular cartilage and subchondral bone in rabbit anterior cruciate ligament transection model].
    Hu H, Zhang L, Li B, Zhang Y, Liu X, Tian F, Cheng T, Wang Z.
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2009 Dec; 23(12):1474-81. PubMed ID: 20073314
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  • 9. Selective inhibition of inducible nitric oxide synthase reduces progression of experimental osteoarthritis in vivo: possible link with the reduction in chondrocyte apoptosis and caspase 3 level.
    Pelletier JP, Jovanovic DV, Lascau-Coman V, Fernandes JC, Manning PT, Connor JR, Currie MG, Martel-Pelletier J.
    Arthritis Rheum; 2000 Jun; 43(6):1290-9. PubMed ID: 10857787
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  • 10. Esculetin (dihydroxycoumarin) inhibits the production of matrix metalloproteinases in cartilage explants, and oral administration of its prodrug, CPA-926, suppresses cartilage destruction in rabbit experimental osteoarthritis.
    Yamada H, Watanabe K, Saito T, Hayashi H, Niitani Y, Kikuchi T, Ito A, Fujikawa K, Lohmander LS.
    J Rheumatol; 1999 Mar; 26(3):654-62. PubMed ID: 10090178
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  • 11. The in situ up-regulation of chondrocyte interleukin-1-converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide.
    Boileau C, Martel-Pelletier J, Moldovan F, Jouzeau JY, Netter P, Manning PT, Pelletier JP.
    Arthritis Rheum; 2002 Oct; 46(10):2637-47. PubMed ID: 12384922
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  • 12. Licofelone (ML-3000), a dual inhibitor of 5-lipoxygenase and cyclooxygenase, reduces the level of cartilage chondrocyte death in vivo in experimental dog osteoarthritis: inhibition of pro-apoptotic factors.
    Boileau C, Martel-Pelletier J, Jouzeau JY, Netter P, Moldovan F, Laufer S, Tries S, Pelletier JP.
    J Rheumatol; 2002 Jul; 29(7):1446-53. PubMed ID: 12136904
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  • 13. Licofelone reduces progression of structural changes in a canine model of osteoarthritis under curative conditions: effect on protease expression and activity.
    Moreau M, Boileau C, Martel-Pelletier J, Brunet J, Laufer S, Pelletier JP.
    J Rheumatol; 2006 Jun; 33(6):1176-83. PubMed ID: 16652435
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  • 14. Glucosamine sulfate reduces experimental osteoarthritis and nociception in rats: association with changes of mitogen-activated protein kinase in chondrocytes.
    Wen ZH, Tang CC, Chang YC, Huang SY, Hsieh SP, Lee CH, Huang GS, Ng HF, Neoh CA, Hsieh CS, Chen WF, Jean YH.
    Osteoarthritis Cartilage; 2010 Sep; 18(9):1192-202. PubMed ID: 20510383
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  • 15. Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms.
    Thiel MJ, Schaefer CJ, Lesch ME, Mobley JL, Dudley DT, Tecle H, Barrett SD, Schrier DJ, Flory CM.
    Arthritis Rheum; 2007 Oct; 56(10):3347-57. PubMed ID: 17907188
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  • 16. Hepatocyte growth factor induction of collagenase 3 production in human osteoarthritic cartilage: involvement of the stress-activated protein kinase/c-Jun N-terminal kinase pathway and a sensitive p38 mitogen-activated protein kinase inhibitor cascade.
    Reboul P, Pelletier JP, Tardif G, Benderdour M, Ranger P, Bottaro DP, Martel-Pelletier J.
    Arthritis Rheum; 2001 Jan; 44(1):73-84. PubMed ID: 11212179
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  • 17. Intra-articular injection of the selective cyclooxygenase-2 inhibitor meloxicam (Mobic) reduces experimental osteoarthritis and nociception in rats.
    Wen ZH, Tang CC, Chang YC, Huang SY, Chen CH, Wu SC, Hsieh SP, Hsieh CS, Wang KY, Lin SY, Lee HL, Lee CH, Kuo HC, Chen WF, Jean YH.
    Osteoarthritis Cartilage; 2013 Dec; 21(12):1976-86. PubMed ID: 24084190
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  • 18. Upregulation of urokinase-type plasminogen activator and inhibitor and gelatinase expression via 3 mitogen-activated protein kinases and PI3K pathways during the early development of osteoarthritis.
    Hsieh YS, Yang SF, Lue KH, Chu SC, Li TJ, Lu KH.
    J Rheumatol; 2007 Apr; 34(4):785-93. PubMed ID: 17299841
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  • 19. The therapeutic effects of tenidap in canine experimental osteoarthritis: relationship with biochemical markers.
    Jovanovic D, Caron JP, Martel-Pelletier J, Fernandes JC, Ricketts T, Pelletier JP.
    J Rheumatol; 1997 May; 24(5):916-25. PubMed ID: 9150082
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  • 20. Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: associations with degenerative changes.
    Tetlow LC, Adlam DJ, Woolley DE.
    Arthritis Rheum; 2001 Mar; 44(3):585-94. PubMed ID: 11263773
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