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386 related items for PubMed ID: 12796698

  • 1. Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells.
    Oades GM, Senaratne SG, Clarke IA, Kirby RS, Colston KW.
    J Urol; 2003 Jul; 170(1):246-52. PubMed ID: 12796698
    [Abstract] [Full Text] [Related]

  • 2. Zoledronic acid induces apoptosis and inhibits adhesion to mineralized matrix in prostate cancer cells via inhibition of protein prenylation.
    Coxon JP, Oades GM, Kirby RS, Colston KW.
    BJU Int; 2004 Jul; 94(1):164-70. PubMed ID: 15217454
    [Abstract] [Full Text] [Related]

  • 3. Pamidronate inhibits antiapoptotic bcl-2 expression through inhibition of the mevalonate pathway in prostate cancer PC-3 cells.
    Iguchi K, Tatsuda Y, Usui S, Hirano K.
    Eur J Pharmacol; 2010 Sep 01; 641(1):35-40. PubMed ID: 20519142
    [Abstract] [Full Text] [Related]

  • 4. A novel hydroxamic acid compound, BMD188, demonstrates anti-prostate cancer effects by inducing apoptosis. I: In vitro studies.
    Li L, Zhu Z, Joshi B, Porter AT, Tang DG.
    Anticancer Res; 1999 Sep 01; 19(1A):51-60. PubMed ID: 10226524
    [Abstract] [Full Text] [Related]

  • 5. The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel.
    Jagdev SP, Coleman RE, Shipman CM, Rostami-H A, Croucher PI.
    Br J Cancer; 2001 Apr 20; 84(8):1126-34. PubMed ID: 11308265
    [Abstract] [Full Text] [Related]

  • 6. The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation.
    Peng H, Sohara Y, Moats RA, Nelson MD, Groshen SG, Ye W, Reynolds CP, DeClerck YA.
    Cancer Res; 2007 Oct 01; 67(19):9346-55. PubMed ID: 17909043
    [Abstract] [Full Text] [Related]

  • 7. Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway.
    Virtanen SS, Väänänen HK, Härkönen PL, Lakkakorpi PT.
    Cancer Res; 2002 May 01; 62(9):2708-14. PubMed ID: 11980672
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of protein prenylation by bisphosphonates causes sustained activation of Rac, Cdc42, and Rho GTPases.
    Dunford JE, Rogers MJ, Ebetino FH, Phipps RJ, Coxon FP.
    J Bone Miner Res; 2006 May 01; 21(5):684-94. PubMed ID: 16734383
    [Abstract] [Full Text] [Related]

  • 9. Indirect antitumor effects of bisphosphonates on prostatic LNCaP cells co-cultured with bone cells.
    Tanaka T, Kawashima H, Ohnishi K, Matsumura K, Yoshimura R, Matsuyama M, Kuratsukuri K, Nakatani T.
    Anticancer Res; 2009 Apr 01; 29(4):1089-94. PubMed ID: 19414350
    [Abstract] [Full Text] [Related]

  • 10. Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells.
    Goffinet M, Thoulouzan M, Pradines A, Lajoie-Mazenc I, Weinbaum C, Faye JC, Séronie-Vivien S.
    BMC Cancer; 2006 Mar 15; 6():60. PubMed ID: 16539721
    [Abstract] [Full Text] [Related]

  • 11. Zoledronic acid in combination with serine/threonine phosphatase inhibitors induces enhanced cytotoxicity and apoptosis in hormone-refractory prostate cancer cell lines by decreasing the activities of PP1 and PP2A.
    Cirak Y, Varol U, Atmaca H, Kisim A, Sezgin C, Karabulut B, Uzunoglu S, Uslu R, Karaca B.
    BJU Int; 2012 Dec 15; 110(11 Pt C):E1147-54. PubMed ID: 22882676
    [Abstract] [Full Text] [Related]

  • 12. Cytostatic and apoptotic effects of bisphosphonates on prostate cancer cells.
    Dumon JC, Journé F, Kheddoumi N, Lagneaux L, Body JJ.
    Eur Urol; 2004 Apr 15; 45(4):521-8; discussion 528-9. PubMed ID: 15041119
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells.
    Merrell MA, Wakchoure S, Lehenkari PP, Harris KW, Selander KS.
    Eur J Pharmacol; 2007 Sep 10; 570(1-3):27-37. PubMed ID: 17640631
    [Abstract] [Full Text] [Related]

  • 14. The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro.
    Mitrofan LM, Pelkonen J, Mönkkönen J.
    Bone; 2009 Dec 10; 45(6):1153-60. PubMed ID: 19699819
    [Abstract] [Full Text] [Related]

  • 15. Increased anti-tumour effects of doxorubicin and zoledronic acid in prostate cancer cells in vitro: supporting the benefits of combination therapy.
    Clyburn RD, Reid P, Evans CA, Lefley DV, Holen I.
    Cancer Chemother Pharmacol; 2010 Apr 10; 65(5):969-78. PubMed ID: 19730863
    [Abstract] [Full Text] [Related]

  • 16. Bisphosphonates: preclinical review.
    Green JR.
    Oncologist; 2004 Apr 10; 9 Suppl 4():3-13. PubMed ID: 15459425
    [Abstract] [Full Text] [Related]

  • 17. Nitroxide tempo, a small molecule, induces apoptosis in prostate carcinoma cells and suppresses tumor growth in athymic mice.
    Suy S, Mitchell JB, Samuni A, Mueller S, Kasid U.
    Cancer; 2005 Mar 15; 103(6):1302-13. PubMed ID: 15685617
    [Abstract] [Full Text] [Related]

  • 18. Apigenin drives the production of reactive oxygen species and initiates a mitochondrial mediated cell death pathway in prostate epithelial cells.
    Morrissey C, O'Neill A, Spengler B, Christoffel V, Fitzpatrick JM, Watson RW.
    Prostate; 2005 May 01; 63(2):131-42. PubMed ID: 15486995
    [Abstract] [Full Text] [Related]

  • 19. Bisphosphonate treatment inhibits the growth of prostate cancer cells.
    Lee MV, Fong EM, Singer FR, Guenette RS.
    Cancer Res; 2001 Mar 15; 61(6):2602-8. PubMed ID: 11289137
    [Abstract] [Full Text] [Related]

  • 20. Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells.
    O'Connor K, Gill C, Tacke M, Rehmann FJ, Strohfeldt K, Sweeney N, Fitzpatrick JM, Watson RW.
    Apoptosis; 2006 Jul 15; 11(7):1205-14. PubMed ID: 16699961
    [Abstract] [Full Text] [Related]

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