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547 related items for PubMed ID: 12805374

  • 1. Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.
    Gavrilova O, Haluzik M, Matsusue K, Cutson JJ, Johnson L, Dietz KR, Nicol CJ, Vinson C, Gonzalez FJ, Reitman ML.
    J Biol Chem; 2003 Sep 05; 278(36):34268-76. PubMed ID: 12805374
    [Abstract] [Full Text] [Related]

  • 2. Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones.
    Chao L, Marcus-Samuels B, Mason MM, Moitra J, Vinson C, Arioglu E, Gavrilova O, Reitman ML.
    J Clin Invest; 2000 Nov 05; 106(10):1221-8. PubMed ID: 11086023
    [Abstract] [Full Text] [Related]

  • 3. A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.
    Murakami K, Tobe K, Ide T, Mochizuki T, Ohashi M, Akanuma Y, Yazaki Y, Kadowaki T.
    Diabetes; 1998 Dec 05; 47(12):1841-7. PubMed ID: 9836514
    [Abstract] [Full Text] [Related]

  • 4. Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice.
    Memon RA, Tecott LH, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, Feingold KR.
    Endocrinology; 2000 Nov 05; 141(11):4021-31. PubMed ID: 11089532
    [Abstract] [Full Text] [Related]

  • 5. Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones.
    Norris AW, Chen L, Fisher SJ, Szanto I, Ristow M, Jozsi AC, Hirshman MF, Rosen ED, Goodyear LJ, Gonzalez FJ, Spiegelman BM, Kahn CR.
    J Clin Invest; 2003 Aug 05; 112(4):608-18. PubMed ID: 12925701
    [Abstract] [Full Text] [Related]

  • 6. Sex dimorphic actions of rosiglitazone in generalised peroxisome proliferator-activated receptor-gamma (PPAR-gamma)-deficient mice.
    Duan SZ, Usher MG, Foley EL, Milstone DS, Brosius FC, Mortensen RM.
    Diabetologia; 2010 Jul 05; 53(7):1493-505. PubMed ID: 20401461
    [Abstract] [Full Text] [Related]

  • 7. Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation.
    Koh EH, Kim MS, Park JY, Kim HS, Youn JY, Park HS, Youn JH, Lee KU.
    Diabetes; 2003 Sep 05; 52(9):2331-7. PubMed ID: 12941773
    [Abstract] [Full Text] [Related]

  • 8. Diabetic KKAy mice exhibit increased hepatic PPARgamma1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones.
    Bedoucha M, Atzpodien E, Boelsterli UA.
    J Hepatol; 2001 Jul 05; 35(1):17-23. PubMed ID: 11495036
    [Abstract] [Full Text] [Related]

  • 9. Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma.
    Savage DB, Tan GD, Acerini CL, Jebb SA, Agostini M, Gurnell M, Williams RL, Umpleby AM, Thomas EL, Bell JD, Dixon AK, Dunne F, Boiani R, Cinti S, Vidal-Puig A, Karpe F, Chatterjee VK, O'Rahilly S.
    Diabetes; 2003 Apr 05; 52(4):910-7. PubMed ID: 12663460
    [Abstract] [Full Text] [Related]

  • 10. Novel genes regulated by the insulin sensitizer rosiglitazone during adipocyte differentiation.
    Albrektsen T, Frederiksen KS, Holmes WE, Boel E, Taylor K, Fleckner J.
    Diabetes; 2002 Apr 05; 51(4):1042-51. PubMed ID: 11916924
    [Abstract] [Full Text] [Related]

  • 11. The effects of fibrates and thiazolidinediones on plasma triglyceride metabolism are mediated by distinct peroxisome proliferator activated receptors (PPARs).
    Staels B, Schoonjans K, Fruchart JC, Auwerx J.
    Biochimie; 1997 Apr 05; 79(2-3):95-9. PubMed ID: 9209702
    [Abstract] [Full Text] [Related]

  • 12. A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice.
    Fukui Y, Masui S, Osada S, Umesono K, Motojima K.
    Diabetes; 2000 May 05; 49(5):759-67. PubMed ID: 10905484
    [Abstract] [Full Text] [Related]

  • 13. Regulation of triglyceride metabolism by PPARs: fibrates and thiazolidinediones have distinct effects.
    Auwerx J, Schoonjans K, Fruchart JC, Staels B.
    J Atheroscler Thromb; 1996 May 05; 3(2):81-9. PubMed ID: 9226459
    [Abstract] [Full Text] [Related]

  • 14. Differential activation of peroxisome proliferator-activated receptor-gamma by troglitazone and rosiglitazone.
    Camp HS, Li O, Wise SC, Hong YH, Frankowski CL, Shen X, Vanbogelen R, Leff T.
    Diabetes; 2000 Apr 05; 49(4):539-47. PubMed ID: 10871190
    [Abstract] [Full Text] [Related]

  • 15. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle.
    He W, Barak Y, Hevener A, Olson P, Liao D, Le J, Nelson M, Ong E, Olefsky JM, Evans RM.
    Proc Natl Acad Sci U S A; 2003 Dec 23; 100(26):15712-7. PubMed ID: 14660788
    [Abstract] [Full Text] [Related]

  • 16. Peroxisome proliferator-activated receptors gamma and alpha mediate in vivo regulation of uncoupling protein (UCP-1, UCP-2, UCP-3) gene expression.
    Kelly LJ, Vicario PP, Thompson GM, Candelore MR, Doebber TW, Ventre J, Wu MS, Meurer R, Forrest MJ, Conner MW, Cascieri MA, Moller DE.
    Endocrinology; 1998 Dec 23; 139(12):4920-7. PubMed ID: 9832429
    [Abstract] [Full Text] [Related]

  • 17. Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.
    Liu LF, Purushotham A, Wendel AA, Belury MA.
    Am J Physiol Gastrointest Liver Physiol; 2007 Jun 23; 292(6):G1671-82. PubMed ID: 17322064
    [Abstract] [Full Text] [Related]

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