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1842 related items for PubMed ID: 12807727

  • 1. Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.
    Woo JH, Kim YH, Choi YJ, Kim DG, Lee KS, Bae JH, Min DS, Chang JS, Jeong YJ, Lee YH, Park JW, Kwon TK.
    Carcinogenesis; 2003 Jul; 24(7):1199-208. PubMed ID: 12807727
    [Abstract] [Full Text] [Related]

  • 2. Arsenic trioxide-induced apoptosis in U937 cells involve generation of reactive oxygen species and inhibition of Akt.
    Choi YJ, Park JW, Suh SI, Mun KC, Bae JH, Song DK, Kim SP, Kwon TK.
    Int J Oncol; 2002 Sep; 21(3):603-10. PubMed ID: 12168106
    [Abstract] [Full Text] [Related]

  • 3. Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer.
    Shankar S, Srivastava RK.
    Int J Oncol; 2007 Apr; 30(4):905-18. PubMed ID: 17332930
    [Abstract] [Full Text] [Related]

  • 4. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation.
    Choi MJ, Park EJ, Oh JH, Min KJ, Yang ES, Kim YH, Lee TJ, Kim SH, Choi YH, Park JW, Kwon TK.
    Chem Biol Interact; 2011 Apr 25; 190(2-3):102-8. PubMed ID: 21334318
    [Abstract] [Full Text] [Related]

  • 5. Rituximab modifies the cisplatin-mitochondrial signaling pathway, resulting in apoptosis in cisplatin-resistant non-Hodgkin's lymphoma.
    Alas S, Ng CP, Bonavida B.
    Clin Cancer Res; 2002 Mar 25; 8(3):836-45. PubMed ID: 11895917
    [Abstract] [Full Text] [Related]

  • 6. Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl.
    Anto RJ, Mukhopadhyay A, Denning K, Aggarwal BB.
    Carcinogenesis; 2002 Jan 25; 23(1):143-50. PubMed ID: 11756235
    [Abstract] [Full Text] [Related]

  • 7. Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells.
    Park MT, Kang JA, Choi JA, Kang CM, Kim TH, Bae S, Kang S, Kim S, Choi WI, Cho CK, Chung HY, Lee YS, Lee SJ.
    Clin Cancer Res; 2003 Feb 25; 9(2):878-85. PubMed ID: 12576463
    [Abstract] [Full Text] [Related]

  • 8. Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.
    Watson JL, Greenshields A, Hill R, Hilchie A, Lee PW, Giacomantonio CA, Hoskin DW.
    Mol Carcinog; 2010 Jan 25; 49(1):13-24. PubMed ID: 19676105
    [Abstract] [Full Text] [Related]

  • 9. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW, Chong SY, Kim JY, Eom JI, Jeung HK, Maeng HY, Lee ST, Min YH.
    Clin Cancer Res; 2003 Oct 15; 9(13):5018-27. PubMed ID: 14581377
    [Abstract] [Full Text] [Related]

  • 10. Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.
    Rashmi R, Kumar S, Karunagaran D.
    Carcinogenesis; 2005 Apr 15; 26(4):713-23. PubMed ID: 15661804
    [Abstract] [Full Text] [Related]

  • 11. Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.
    Rashmi R, Kumar S, Karunagaran D.
    Carcinogenesis; 2004 Oct 15; 25(10):1867-77. PubMed ID: 15205359
    [Abstract] [Full Text] [Related]

  • 12. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 13. Characterization of distinct consecutive phases in non-genotoxic p53-induced apoptosis of Ewing tumor cells and the rate-limiting role of caspase 8.
    Kovar H, Jug G, Printz D, Bartl S, Schmid G, Wesierska-Gadek J.
    Oncogene; 2000 Aug 24; 19(36):4096-107. PubMed ID: 10962570
    [Abstract] [Full Text] [Related]

  • 14. Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor beta in rat fetal hepatocytes.
    Herrera B, Fernández M, Alvarez AM, Roncero C, Benito M, Gil J, Fabregat I.
    Hepatology; 2001 Sep 24; 34(3):548-56. PubMed ID: 11526541
    [Abstract] [Full Text] [Related]

  • 15. N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells.
    Kim BM, Choi YJ, Han Y, Yun YS, Hong SH.
    Toxicol Appl Pharmacol; 2009 Aug 15; 239(1):87-97. PubMed ID: 19481559
    [Abstract] [Full Text] [Related]

  • 16. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M, Reese E, Dai Y, Bauer C, Payne SG, Dent P, Spiegel S, Grant S.
    Cancer Res; 2005 Mar 15; 65(6):2422-32. PubMed ID: 15781658
    [Abstract] [Full Text] [Related]

  • 17. Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway.
    Oh SH, Lee BH, Lim SC.
    Biochem Pharmacol; 2004 Nov 01; 68(9):1845-55. PubMed ID: 15450950
    [Abstract] [Full Text] [Related]

  • 18. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):49-60. PubMed ID: 17341418
    [Abstract] [Full Text] [Related]

  • 19. N-phenethyl-2-phenylacetamide isolated from Xenorhabdus nematophilus induces apoptosis through caspase activation and calpain-mediated Bax cleavage in U937 cells.
    Hwang SY, Paik S, Park SH, Kim HS, Lee IS, Kim SP, Baek WK, Suh MH, Kwon TK, Park JW, Park JB, Lee JJ, Suh SI.
    Int J Oncol; 2003 Jan 01; 22(1):151-7. PubMed ID: 12469198
    [Abstract] [Full Text] [Related]

  • 20. Overexpression of bcl-2 or bcl-XL fails to inhibit apoptosis mediated by a novel retinoid.
    Fontana JA, Sun RJ, Rishi AK, Dawson MI, Ordónez JV, Zhang Y, Tschang SH, Bhalla K, Han Z, Wyche J, Poirer G, Sheikh MS, Shroot B, Reichert U.
    Oncol Res; 1998 Jan 01; 10(6):313-24. PubMed ID: 9848102
    [Abstract] [Full Text] [Related]


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