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Journal Abstract Search


459 related items for PubMed ID: 12814936

  • 1. TACE/ADAM17 processing of EGFR ligands indicates a role as a physiological convertase.
    Lee DC, Sunnarborg SW, Hinkle CL, Myers TJ, Stevenson MY, Russell WE, Castner BJ, Gerhart MJ, Paxton RJ, Black RA, Chang A, Jackson LF.
    Ann N Y Acad Sci; 2003 May; 995():22-38. PubMed ID: 12814936
    [Abstract] [Full Text] [Related]

  • 2. Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency.
    Hinkle CL, Sunnarborg SW, Loiselle D, Parker CE, Stevenson M, Russell WE, Lee DC.
    J Biol Chem; 2004 Jun 04; 279(23):24179-88. PubMed ID: 15066986
    [Abstract] [Full Text] [Related]

  • 3. Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability.
    Sunnarborg SW, Hinkle CL, Stevenson M, Russell WE, Raska CS, Peschon JJ, Castner BJ, Gerhart MJ, Paxton RJ, Black RA, Lee DC.
    J Biol Chem; 2002 Apr 12; 277(15):12838-45. PubMed ID: 11823465
    [Abstract] [Full Text] [Related]

  • 4. Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands.
    Sahin U, Weskamp G, Kelly K, Zhou HM, Higashiyama S, Peschon J, Hartmann D, Saftig P, Blobel CP.
    J Cell Biol; 2004 Mar 01; 164(5):769-79. PubMed ID: 14993236
    [Abstract] [Full Text] [Related]

  • 5. Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme.
    Merlos-Suárez A, Ruiz-Paz S, Baselga J, Arribas J.
    J Biol Chem; 2001 Dec 21; 276(51):48510-7. PubMed ID: 11600492
    [Abstract] [Full Text] [Related]

  • 6. Transforming growth factor alpha (TGF-alpha) and other targets of tumor necrosis factor-alpha converting enzyme (TACE) in murine polycystic kidney disease.
    Nemo R, Murcia N, Dell KM.
    Pediatr Res; 2005 May 21; 57(5 Pt 1):732-7. PubMed ID: 15774823
    [Abstract] [Full Text] [Related]

  • 7. Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme.
    Nishi E, Hiraoka Y, Yoshida K, Okawa K, Kita T.
    J Biol Chem; 2006 Oct 13; 281(41):31164-72. PubMed ID: 16923819
    [Abstract] [Full Text] [Related]

  • 8. TACE is required for fetal murine cardiac development and modeling.
    Shi W, Chen H, Sun J, Buckley S, Zhao J, Anderson KD, Williams RG, Warburton D.
    Dev Biol; 2003 Sep 15; 261(2):371-80. PubMed ID: 14499647
    [Abstract] [Full Text] [Related]

  • 9. TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells.
    Gschwind A, Hart S, Fischer OM, Ullrich A.
    EMBO J; 2003 May 15; 22(10):2411-21. PubMed ID: 12743035
    [Abstract] [Full Text] [Related]

  • 10. TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer.
    Merchant NB, Voskresensky I, Rogers CM, Lafleur B, Dempsey PJ, Graves-Deal R, Revetta F, Foutch AC, Rothenberg ML, Washington MK, Coffey RJ.
    Clin Cancer Res; 2008 Feb 15; 14(4):1182-91. PubMed ID: 18281553
    [Abstract] [Full Text] [Related]

  • 11. The heparin-binding domain of amphiregulin necessitates the precursor pro-region for growth factor secretion.
    Thorne BA, Plowman GD.
    Mol Cell Biol; 1994 Mar 15; 14(3):1635-46. PubMed ID: 8114701
    [Abstract] [Full Text] [Related]

  • 12. Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor.
    Hart S, Fischer OM, Ullrich A.
    Cancer Res; 2004 Mar 15; 64(6):1943-50. PubMed ID: 15026328
    [Abstract] [Full Text] [Related]

  • 13. Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.
    Horiuchi K, Le Gall S, Schulte M, Yamaguchi T, Reiss K, Murphy G, Toyama Y, Hartmann D, Saftig P, Blobel CP.
    Mol Biol Cell; 2007 Jan 15; 18(1):176-88. PubMed ID: 17079736
    [Abstract] [Full Text] [Related]

  • 14. Multiple metalloproteinases process protransforming growth factor-alpha (proTGF-alpha).
    Hinkle CL, Mohan MJ, Lin P, Yeung N, Rasmussen F, Milla ME, Moss ML.
    Biochemistry; 2003 Feb 25; 42(7):2127-36. PubMed ID: 12590602
    [Abstract] [Full Text] [Related]

  • 15. Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer.
    Tanaka Y, Miyamoto S, Suzuki SO, Oki E, Yagi H, Sonoda K, Yamazaki A, Mizushima H, Maehara Y, Mekada E, Nakano H.
    Clin Cancer Res; 2005 Jul 01; 11(13):4783-92. PubMed ID: 16000575
    [Abstract] [Full Text] [Related]

  • 16. 5-HT2A receptor induces ERK phosphorylation and proliferation through ADAM-17 tumor necrosis factor-alpha-converting enzyme (TACE) activation and heparin-bound epidermal growth factor-like growth factor (HB-EGF) shedding in mesangial cells.
    Göőz M, Göőz P, Luttrell LM, Raymond JR.
    J Biol Chem; 2006 Jul 28; 281(30):21004-21012. PubMed ID: 16737974
    [Abstract] [Full Text] [Related]

  • 17. Hormone-induced expression of tumor necrosis factor alpha-converting enzyme/A disintegrin and metalloprotease-17 impacts porcine cumulus cell oocyte complex expansion and meiotic maturation via ligand activation of the epidermal growth factor receptor.
    Yamashita Y, Kawashima I, Yanai Y, Nishibori M, Richards JS, Shimada M.
    Endocrinology; 2007 Dec 28; 148(12):6164-75. PubMed ID: 17901238
    [Abstract] [Full Text] [Related]

  • 18. Leptin stimulates the proliferation of human oesophageal adenocarcinoma cells via HB-EGF and Tgfalpha mediated transactivation of the epidermal growth factor receptor.
    Ogunwobi OO, Beales IL.
    Br J Biomed Sci; 2008 Dec 28; 65(3):121-7. PubMed ID: 18986098
    [Abstract] [Full Text] [Related]

  • 19. N-terminal cleavage of proTGFalpha occurs at the cell surface by a TACE-independent activity.
    Juanes PP, Ferreira L, Montero JC, Arribas J, Pandiella A.
    Biochem J; 2005 Jul 01; 389(Pt 1):161-72. PubMed ID: 15777285
    [Abstract] [Full Text] [Related]

  • 20. The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4.
    Riese DJ, Kim ED, Elenius K, Buckley S, Klagsbrun M, Plowman GD, Stern DF.
    J Biol Chem; 1996 Aug 16; 271(33):20047-52. PubMed ID: 8702723
    [Abstract] [Full Text] [Related]


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