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263 related items for PubMed ID: 12815069

  • 1. Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis.
    Yang QH, Church-Hajduk R, Ren J, Newton ML, Du C.
    Genes Dev; 2003 Jun 15; 17(12):1487-96. PubMed ID: 12815069
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  • 2. Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways.
    Suzuki Y, Takahashi-Niki K, Akagi T, Hashikawa T, Takahashi R.
    Cell Death Differ; 2004 Feb 15; 11(2):208-16. PubMed ID: 14605674
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  • 4. Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2.
    Srinivasula SM, Gupta S, Datta P, Zhang Z, Hegde R, Cheong N, Fernandes-Alnemri T, Alnemri ES.
    J Biol Chem; 2003 Aug 22; 278(34):31469-72. PubMed ID: 12835328
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  • 5. Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi.
    Martins LM, Turk BE, Cowling V, Borg A, Jarrell ET, Cantley LC, Downward J.
    J Biol Chem; 2003 Dec 05; 278(49):49417-27. PubMed ID: 14512424
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  • 10. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif.
    Martins LM, Iaccarino I, Tenev T, Gschmeissner S, Totty NF, Lemoine NR, Savopoulos J, Gray CW, Creasy CL, Dingwall C, Downward J.
    J Biol Chem; 2002 Jan 04; 277(1):439-44. PubMed ID: 11602612
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  • 12. Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease.
    Goffredo D, Rigamonti D, Zuccato C, Tartari M, Valenza M, Cattaneo E.
    Pharmacol Res; 2005 Aug 04; 52(2):140-50. PubMed ID: 15967379
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  • 13. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death.
    Suzuki Y, Imai Y, Nakayama H, Takahashi K, Takio K, Takahashi R.
    Mol Cell; 2001 Sep 04; 8(3):613-21. PubMed ID: 11583623
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  • 14. The proteases HtrA2/Omi and UCH-L1 regulate TNF-induced necroptosis.
    Sosna J, Voigt S, Mathieu S, Kabelitz D, Trad A, Janssen O, Meyer-Schwesinger C, Schütze S, Adam D.
    Cell Commun Signal; 2013 Oct 03; 11():76. PubMed ID: 24090154
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  • 15. Endogenously released Smac is insufficient to mediate cell death of human lung carcinoma in response to etoposide.
    Bartling B, Lewensohn R, Zhivotovsky B.
    Exp Cell Res; 2004 Aug 01; 298(1):83-95. PubMed ID: 15242764
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  • 18. Mammalian mitochondrial IAP binding proteins.
    Vaux DL, Silke J.
    Biochem Biophys Res Commun; 2003 May 09; 304(3):499-504. PubMed ID: 12729584
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  • 19. Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15.
    Trencia A, Fiory F, Maitan MA, Vito P, Barbagallo AP, Perfetti A, Miele C, Ungaro P, Oriente F, Cilenti L, Zervos AS, Formisano P, Beguinot F.
    J Biol Chem; 2004 Nov 05; 279(45):46566-72. PubMed ID: 15328349
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  • 20. Motoneuron resistance to apoptotic cell death in vivo correlates with the ratio between X-linked inhibitor of apoptosis proteins (XIAPs) and its inhibitor, XIAP-associated factor 1.
    Perrelet D, Perrin FE, Liston P, Korneluk RG, MacKenzie A, Ferrer-Alcon M, Kato AC.
    J Neurosci; 2004 Apr 14; 24(15):3777-85. PubMed ID: 15084658
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