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275 related items for PubMed ID: 12815165

  • 1. Molecular determination of agouti-related protein binding to human melanocortin-4 receptor.
    Yang Y, Chen M, Lai Y, Gantz I, Yagmurlu A, Georgeson KE, Harmon CM.
    Mol Pharmacol; 2003 Jul; 64(1):94-103. PubMed ID: 12815165
    [Abstract] [Full Text] [Related]

  • 2. Molecular basis of melanocortin-4 receptor for AGRP inverse agonism.
    Chen M, Celik A, Georgeson KE, Harmon CM, Yang Y.
    Regul Pept; 2006 Sep 11; 136(1-3):40-9. PubMed ID: 16820227
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  • 5. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A, Wang XS, Joseph CG, Xiang Z, Bauzo RM, Scott JW, Sorensen NB, Shaw AM, Millard WJ, Richards NG, Haskell-Luevano C.
    J Med Chem; 2004 Apr 22; 47(9):2194-207. PubMed ID: 15084118
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  • 6. Molecular interaction of Agouti protein and Agouti-related protein with human melanocortin receptors.
    Tota MR, Smith TS, Mao C, MacNeil T, Mosley RT, Van der Ploeg LH, Fong TM.
    Biochemistry; 1999 Jan 19; 38(3):897-904. PubMed ID: 9893984
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  • 8. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA, Doufexis M, Kapas S, Chhajlani V.
    Biochem Biophys Res Commun; 2001 Mar 09; 281(4):851-7. PubMed ID: 11237737
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  • 9. Chimeras of the agouti-related protein: insights into agonist and antagonist selectivity of melanocortin receptors.
    Jackson PJ, Yu B, Hunrichs B, Thompson DA, Chai B, Gantz I, Millhauser GL.
    Peptides; 2005 Oct 09; 26(10):1978-87. PubMed ID: 16009463
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  • 10. Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants.
    Haskell-Luevano C, Cone RD, Monck EK, Wan YP.
    Biochemistry; 2001 May 22; 40(20):6164-79. PubMed ID: 11352754
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  • 11. Structure-activity relationship of (1-aryl-2-piperazinylethyl)piperazines: antagonists for the AGRP/melanocortin receptor binding.
    Arasasingham PN, Fotsch C, Ouyang X, Norman MH, Kelly MG, Stark KL, Karbon B, Hale C, Baumgartner JW, Zambrano M, Cheetham J, Tamayo NA.
    J Med Chem; 2003 Jan 02; 46(1):9-11. PubMed ID: 12502354
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  • 12. Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
    Haskell-Luevano C, Hendrata S, North C, Sawyer TK, Hadley ME, Hruby VJ, Dickinson C, Gantz I.
    J Med Chem; 1997 Jul 04; 40(14):2133-9. PubMed ID: 9216831
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  • 13. Substituted NDP-MSH peptides paired with mutant melanocortin-4 receptors demonstrate the role of transmembrane 6 in receptor activation.
    Fleck BA, Ling N, Chen C.
    Biochemistry; 2007 Sep 18; 46(37):10473-83. PubMed ID: 17713970
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  • 14. The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs.
    Klovins J, Haitina T, Fridmanis D, Kilianova Z, Kapa I, Fredriksson R, Gallo-Payet N, Schiöth HB.
    Mol Biol Evol; 2004 Mar 18; 21(3):563-79. PubMed ID: 14694081
    [Abstract] [Full Text] [Related]

  • 15. Molecular mechanism of the intracellular segments of the melanocortin-4 receptor for NDP-MSH signaling.
    Yang Y, Chen M, Loux TJ, Georgeson KE, Harmon CM.
    Biochemistry; 2005 May 10; 44(18):6971-9. PubMed ID: 15865442
    [Abstract] [Full Text] [Related]

  • 16. Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist.
    Xiang Z, Litherland SA, Sorensen NB, Proneth B, Wood MS, Shaw AM, Millard WJ, Haskell-Luevano C.
    Biochemistry; 2006 Jun 13; 45(23):7277-88. PubMed ID: 16752916
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  • 17. Molecular determinants of melanocortin 4 receptor ligand binding and MC4/MC3 receptor selectivity.
    Nickolls SA, Cismowski MI, Wang X, Wolff M, Conlon PJ, Maki RA.
    J Pharmacol Exp Ther; 2003 Mar 13; 304(3):1217-27. PubMed ID: 12604699
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  • 18. Structural characterization and pharmacology of a potent (Cys101-Cys119, Cys110-Cys117) bicyclic agouti-related protein (AGRP) melanocortin receptor antagonist.
    Wilczynski A, Wang XS, Bauzo RM, Xiang Z, Shaw AM, Millard WJ, Richards NG, Edison AS, Haskell-Luevano C.
    J Med Chem; 2004 Nov 04; 47(23):5662-73. PubMed ID: 15509165
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  • 19. Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides.
    Marsh DJ, Hollopeter G, Huszar D, Laufer R, Yagaloff KA, Fisher SL, Burn P, Palmiter RD.
    Nat Genet; 1999 Jan 04; 21(1):119-22. PubMed ID: 9916804
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  • 20. Overview of endogenous and synthetic melanocortin peptides.
    Wilson KR, Todorovic A, Proneth B, Haskell-Luevano C.
    Cell Mol Biol (Noisy-le-grand); 2006 May 30; 52(2):3-20. PubMed ID: 16914082
    [Abstract] [Full Text] [Related]

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