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Journal Abstract Search


181 related items for PubMed ID: 12818695

  • 1. Nitrogen substitution modifies the activity of cytisine on neuronal nicotinic receptor subtypes.
    Carbonnelle E, Sparatore F, Canu-Boido C, Salvagno C, Baldani-Guerra B, Terstappen G, Zwart R, Vijverberg H, Clementi F, Gotti C.
    Eur J Pharmacol; 2003 Jun 20; 471(2):85-96. PubMed ID: 12818695
    [Abstract] [Full Text] [Related]

  • 2. Deletion of the alpha7, beta2, or beta4 nicotinic receptor subunit genes identifies highly expressed subtypes with relatively low affinity for [3H]epibatidine.
    Marks MJ, Whiteaker P, Collins AC.
    Mol Pharmacol; 2006 Sep 20; 70(3):947-59. PubMed ID: 16728647
    [Abstract] [Full Text] [Related]

  • 3. ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors: I. In vitro characterization.
    Donnelly-Roberts DL, Puttfarcken PS, Kuntzweiler TA, Briggs CA, Anderson DJ, Campbell JE, Piattoni-Kaplan M, McKenna DG, Wasicak JT, Holladay MW, Williams M, Arneric SP.
    J Pharmacol Exp Ther; 1998 May 20; 285(2):777-86. PubMed ID: 9580626
    [Abstract] [Full Text] [Related]

  • 4. Long-term exposure to the new nicotinic antagonist 1,2-bisN-cytisinylethane upregulates nicotinic receptor subtypes of SH-SY5Y human neuroblastoma cells.
    Riganti L, Matteoni C, Di Angelantonio S, Nistri A, Gaimarri A, Sparatore F, Canu-Boido C, Clementi F, Gotti C.
    Br J Pharmacol; 2005 Dec 20; 146(8):1096-109. PubMed ID: 16273122
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, binding, and modeling studies of new cytisine derivatives, as ligands for neuronal nicotinic acetylcholine receptor subtypes.
    Tasso B, Canu Boido C, Terranova E, Gotti C, Riganti L, Clementi F, Artali R, Bombieri G, Meneghetti F, Sparatore F.
    J Med Chem; 2009 Jul 23; 52(14):4345-57. PubMed ID: 19548687
    [Abstract] [Full Text] [Related]

  • 6. Neuronal nicotinic receptor beta2 and beta4 subunits confer large differences in agonist binding affinity.
    Parker MJ, Beck A, Luetje CW.
    Mol Pharmacol; 1998 Dec 23; 54(6):1132-9. PubMed ID: 9855644
    [Abstract] [Full Text] [Related]

  • 7. C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists.
    Abin-Carriquiry JA, Voutilainen MH, Barik J, Cassels BK, Iturriaga-Vásquez P, Bermudez I, Durand C, Dajas F, Wonnacott S.
    Eur J Pharmacol; 2006 Apr 24; 536(1-2):1-11. PubMed ID: 16563372
    [Abstract] [Full Text] [Related]

  • 8. Characterization of [(125) I]epibatidine binding and nicotinic agonist-mediated (86) Rb(+) efflux in interpeduncular nucleus and inferior colliculus of beta2 null mutant mice.
    Marks MJ, Whiteaker P, Grady SR, Picciotto MR, McIntosh JM, Collins AC.
    J Neurochem; 2002 Jun 24; 81(5):1102-15. PubMed ID: 12065623
    [Abstract] [Full Text] [Related]

  • 9. Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors.
    Fitch RW, Kaneko Y, Klaperski P, Daly JW, Seitz G, Gündisch D.
    Bioorg Med Chem Lett; 2005 Feb 15; 15(4):1221-4. PubMed ID: 15686946
    [Abstract] [Full Text] [Related]

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  • 12. Ligand specificity of nicotinic acetylcholine receptors in rat spinal cord: studies with nicotine and cytisine.
    Khan IM, Yaksh TL, Taylor P.
    J Pharmacol Exp Ther; 1994 Jul 15; 270(1):159-66. PubMed ID: 8035312
    [Abstract] [Full Text] [Related]

  • 13. Characterization of a series of anabaseine-derived compounds reveals that the 3-(4)-dimethylaminocinnamylidine derivative is a selective agonist at neuronal nicotinic alpha 7/125I-alpha-bungarotoxin receptor subtypes.
    de Fiebre CM, Meyer EM, Henry JC, Muraskin SI, Kem WR, Papke RL.
    Mol Pharmacol; 1995 Jan 15; 47(1):164-71. PubMed ID: 7838125
    [Abstract] [Full Text] [Related]

  • 14. Halogenated cytisine derivatives as agonists at human neuronal nicotinic acetylcholine receptor subtypes.
    Slater YE, Houlihan LM, Maskell PD, Exley R, Bermúdez I, Lukas RJ, Valdivia AC, Cassels BK.
    Neuropharmacology; 2003 Mar 15; 44(4):503-15. PubMed ID: 12646287
    [Abstract] [Full Text] [Related]

  • 15. Nicotine-induced alterations in the expression of nicotinic receptors in primary cultures from human prenatal brain.
    Hellström-Lindahl E, Seiger A, Kjaeldgaard A, Nordberg A.
    Neuroscience; 2001 Mar 15; 105(3):527-34. PubMed ID: 11516820
    [Abstract] [Full Text] [Related]

  • 16. Laminar distribution of nicotinic receptor subtypes in human cerebral cortex as determined by [3H](-)nicotine, [3H]cytisine and [3H]epibatidine in vitro autoradiography.
    Sihver W, Gillberg PG, Nordberg A.
    Neuroscience; 1998 Aug 15; 85(4):1121-33. PubMed ID: 9681951
    [Abstract] [Full Text] [Related]

  • 17. Differential modulation of brain nicotinic acetylcholine receptor function by cytisine, varenicline, and two novel bispidine compounds: emergent properties of a hybrid molecule.
    Peng C, Stokes C, Mineur YS, Picciotto MR, Tian C, Eibl C, Tomassoli I, Guendisch D, Papke RL.
    J Pharmacol Exp Ther; 2013 Nov 15; 347(2):424-37. PubMed ID: 23959137
    [Abstract] [Full Text] [Related]

  • 18. The subunit composition and pharmacology of alpha-Conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay.
    Salminen O, Whiteaker P, Grady SR, Collins AC, McIntosh JM, Marks MJ.
    Neuropharmacology; 2005 Apr 15; 48(5):696-705. PubMed ID: 15814104
    [Abstract] [Full Text] [Related]

  • 19. Regional distribution of nicotinic receptors during prenatal development of human brain and spinal cord.
    Hellström-Lindahl E, Gorbounova O, Seiger A, Mousavi M, Nordberg A.
    Brain Res Dev Brain Res; 1998 Jun 15; 108(1-2):147-60. PubMed ID: 9693793
    [Abstract] [Full Text] [Related]

  • 20. Gene targeting demonstrates that alpha4 nicotinic acetylcholine receptor subunits contribute to expression of diverse [3H]epibatidine binding sites and components of biphasic 86Rb+ efflux with high and low sensitivity to stimulation by acetylcholine.
    Marks MJ, Meinerz NM, Drago J, Collins AC.
    Neuropharmacology; 2007 Sep 15; 53(3):390-405. PubMed ID: 17631923
    [Abstract] [Full Text] [Related]


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