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269 related items for PubMed ID: 12821647

  • 1. Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis.
    Gu H, Botelho RJ, Yu M, Grinstein S, Neel BG.
    J Cell Biol; 2003 Jun 23; 161(6):1151-61. PubMed ID: 12821647
    [Abstract] [Full Text] [Related]

  • 2. Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI.
    Yu M, Lowell CA, Neel BG, Gu H.
    J Immunol; 2006 Feb 15; 176(4):2421-9. PubMed ID: 16456001
    [Abstract] [Full Text] [Related]

  • 3. Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.
    Nyga R, Pecquet C, Harir N, Gu H, Dhennin-Duthille I, Régnier A, Gouilleux-Gruart V, Lassoued K, Gouilleux F.
    Biochem J; 2005 Aug 15; 390(Pt 1):359-66. PubMed ID: 15833084
    [Abstract] [Full Text] [Related]

  • 4. The absence of Grb2-associated binder 2 (Gab2) does not disrupt NK cell development and functions.
    Zompi S, Gu H, Colucci F.
    J Leukoc Biol; 2004 Oct 15; 76(4):896-903. PubMed ID: 15240750
    [Abstract] [Full Text] [Related]

  • 5. Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the gab2 pleckstrin homology domain.
    Parry RV, Whittaker GC, Sims M, Edmead CE, Welham MJ, Ward SG.
    J Immunol; 2006 Jan 01; 176(1):594-602. PubMed ID: 16365455
    [Abstract] [Full Text] [Related]

  • 6. The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway.
    Yu M, Luo J, Yang W, Wang Y, Mizuki M, Kanakura Y, Besmer P, Neel BG, Gu H.
    J Biol Chem; 2006 Sep 29; 281(39):28615-26. PubMed ID: 16873377
    [Abstract] [Full Text] [Related]

  • 7. The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells.
    Xie ZH, Ambudkar I, Siraganian RP.
    J Immunol; 2002 May 01; 168(9):4682-91. PubMed ID: 11971018
    [Abstract] [Full Text] [Related]

  • 8. The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors.
    Wu CJ, O'Rourke DM, Feng GS, Johnson GR, Wang Q, Greene MI.
    Oncogene; 2001 Sep 20; 20(42):6018-25. PubMed ID: 11593409
    [Abstract] [Full Text] [Related]

  • 9. Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration.
    Yu WM, Hawley TS, Hawley RG, Qu CK.
    Blood; 2002 Apr 01; 99(7):2351-9. PubMed ID: 11895767
    [Abstract] [Full Text] [Related]

  • 10. Differential kinase requirements in human and mouse Fc-gamma receptor phagocytosis and endocytosis.
    Huang ZY, Barreda DR, Worth RG, Indik ZK, Kim MK, Chien P, Schreiber AD.
    J Leukoc Biol; 2006 Dec 01; 80(6):1553-62. PubMed ID: 16921024
    [Abstract] [Full Text] [Related]

  • 11. Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes.
    Miyakawa Y, Rojnuckarin P, Habib T, Kaushansky K.
    J Biol Chem; 2001 Jan 26; 276(4):2494-502. PubMed ID: 11054408
    [Abstract] [Full Text] [Related]

  • 12. G-CSF-induced tyrosine phosphorylation of Gab2 is Lyn kinase dependent and associated with enhanced Akt and differentiative, not proliferative, responses.
    Zhu QS, Robinson LJ, Roginskaya V, Corey SJ.
    Blood; 2004 May 01; 103(9):3305-12. PubMed ID: 14656892
    [Abstract] [Full Text] [Related]

  • 13. Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling.
    Zhang X, Lavoie G, Méant A, Aubert L, Cargnello M, Haman A, Hoang T, Roux PP.
    Mol Cell Biol; 2017 Apr 01; 37(7):. PubMed ID: 28096188
    [Abstract] [Full Text] [Related]

  • 14. A yeast two-hybrid study of human p97/Gab2 interactions with its SH2 domain-containing binding partners.
    Crouin C, Arnaud M, Gesbert F, Camonis J, Bertoglio J.
    FEBS Lett; 2001 Apr 27; 495(3):148-53. PubMed ID: 11334882
    [Abstract] [Full Text] [Related]

  • 15. Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.
    Zhang SQ, Tsiaras WG, Araki T, Wen G, Minichiello L, Klein R, Neel BG.
    Mol Cell Biol; 2002 Jun 27; 22(12):4062-72. PubMed ID: 12024020
    [Abstract] [Full Text] [Related]

  • 16. Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis.
    Marshall JG, Booth JW, Stambolic V, Mak T, Balla T, Schreiber AD, Meyer T, Grinstein S.
    J Cell Biol; 2001 Jun 25; 153(7):1369-80. PubMed ID: 11425868
    [Abstract] [Full Text] [Related]

  • 17. HIV-1 down-modulates gamma signaling chain of Fc gamma R in human macrophages: a possible mechanism for inhibition of phagocytosis.
    Kedzierska K, Ellery P, Mak J, Lewin SR, Crowe SM, Jaworowski A.
    J Immunol; 2002 Mar 15; 168(6):2895-903. PubMed ID: 11884460
    [Abstract] [Full Text] [Related]

  • 18. Phosphoinositide3-kinase regulates actin polymerization during delayed phagocytosis of Helicobacter pylori.
    Allen LA, Allgood JA, Han X, Wittine LM.
    J Leukoc Biol; 2005 Jul 15; 78(1):220-30. PubMed ID: 15809290
    [Abstract] [Full Text] [Related]

  • 19. Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1.
    Zhao C, Yu DH, Shen R, Feng GS.
    J Biol Chem; 1999 Jul 09; 274(28):19649-54. PubMed ID: 10391903
    [Abstract] [Full Text] [Related]

  • 20. Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors.
    Nishida K, Yoshida Y, Itoh M, Fukada T, Ohtani T, Shirogane T, Atsumi T, Takahashi-Tezuka M, Ishihara K, Hibi M, Hirano T.
    Blood; 1999 Mar 15; 93(6):1809-16. PubMed ID: 10068651
    [Abstract] [Full Text] [Related]


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