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132 related items for PubMed ID: 12826726

  • 1. The structural basis of Trp192 and the C-terminal region in trichosanthin for activity and conformational stability.
    Ding Y, Too H, Wang Z, Liu Y, Bartlam M, Dong Y, Wong K, Shaw P, Rao Z.
    Protein Eng; 2003 May; 16(5):351-6. PubMed ID: 12826726
    [Abstract] [Full Text] [Related]

  • 2. Crystallization and preliminary x-ray crystallographic studies of trichosanthin delta C7.
    Li X, Ding Y, Wang Z, Liu Y, Dong Y, Shaw P, Rao Z, Too H.
    Protein Pept Lett; 2002 Jun; 9(3):269-73. PubMed ID: 12144525
    [Abstract] [Full Text] [Related]

  • 3. Engineering of a mini-trichosanthin that has lower antigenicity by deleting its C-terminal amino acid residues.
    Chan SH, Shaw PC, Mulot SF, Xu LH, Chan WL, Tam SC, Wong KB.
    Biochem Biophys Res Commun; 2000 Apr 02; 270(1):279-85. PubMed ID: 10733940
    [Abstract] [Full Text] [Related]

  • 4. Change in pH-dependent membrane insertion characteristics of trichosanthin caused by deletion of its last seven C-terminal amino acid residues.
    Zhang F, Lu YJ, Shaw PC, Sui SF.
    Biochemistry (Mosc); 2003 Apr 02; 68(4):436-45. PubMed ID: 12765527
    [Abstract] [Full Text] [Related]

  • 5. Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants.
    Guo Q, Zhou W, Too HM, Li J, Liu Y, Bartlam M, Dong Y, Wong KB, Shaw PC, Rao Z.
    Protein Eng; 2003 Jun 02; 16(6):391-6. PubMed ID: 12874371
    [Abstract] [Full Text] [Related]

  • 6. Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein.
    Shi WW, Wong KB, Shaw PC.
    Toxins (Basel); 2018 Aug 20; 10(8):. PubMed ID: 30127254
    [Abstract] [Full Text] [Related]

  • 7. Anti-HIV-1 property of trichosanthin correlates with its ribosome inactivating activity.
    Wang JH, Nie HL, Tam SC, Huang H, Zheng YT.
    FEBS Lett; 2002 Nov 06; 531(2):295-8. PubMed ID: 12417329
    [Abstract] [Full Text] [Related]

  • 8. Independency of anti-HIV-1 activity from ribosome-inactivating activity of trichosanthin.
    Wang JH, Nie HL, Huang H, Tam SC, Zheng YT.
    Biochem Biophys Res Commun; 2003 Feb 28; 302(1):89-94. PubMed ID: 12593852
    [Abstract] [Full Text] [Related]

  • 9. Crystal structures of the complexes of trichosanthin with four substrate analogs and catalytic mechanism of RNA N-glycosidase.
    Gu YJ, Xia ZX.
    Proteins; 2000 Apr 01; 39(1):37-46. PubMed ID: 10737925
    [Abstract] [Full Text] [Related]

  • 10. Solution structure of human P1•P2 heterodimer provides insights into the role of eukaryotic stalk in recruiting the ribosome-inactivating protein trichosanthin to the ribosome.
    Lee KM, Yusa K, Chu LO, Yu CW, Oono M, Miyoshi T, Ito K, Shaw PC, Wong KB, Uchiumi T.
    Nucleic Acids Res; 2013 Oct 01; 41(18):8776-87. PubMed ID: 23892290
    [Abstract] [Full Text] [Related]

  • 11. Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties.
    Shaw PC, Lee KM, Wong KB.
    Toxicon; 2005 May 01; 45(6):683-9. PubMed ID: 15804517
    [Abstract] [Full Text] [Related]

  • 12. Trichosanthin interacts with acidic ribosomal proteins P0 and P1 and mitotic checkpoint protein MAD2B.
    Chan SH, Hung FS, Chan DS, Shaw PC.
    Eur J Biochem; 2001 Apr 01; 268(7):2107-12. PubMed ID: 11277934
    [Abstract] [Full Text] [Related]

  • 13. Position 120-123, a potential active site of trichosanthin.
    Nie H, Cai X, He X, Xu L, Ke X, Ke Y, Tam SC.
    Life Sci; 1998 Apr 01; 62(6):491-500. PubMed ID: 9464461
    [Abstract] [Full Text] [Related]

  • 14. Role of TYR70 in the N-glycosidase activity of neo-trichosanthin.
    Yan L, Wu S, Li HG, Li JH, Wong RN, Shi QL, Dong YC.
    Toxicon; 1999 Jul 01; 37(7):961-72. PubMed ID: 10484744
    [Abstract] [Full Text] [Related]

  • 15. Trichosanthin induces leakage and membrane fusion of liposome.
    Xia XF, Zhang F, Shaw PC, Sui SF.
    IUBMB Life; 2003 Dec 01; 55(12):681-7. PubMed ID: 14769004
    [Abstract] [Full Text] [Related]

  • 16. Structure of trichosanthin at 1.88 A resolution.
    Zhou K, Fu Z, Chen M, Lin Y, Pan K.
    Proteins; 1994 May 01; 19(1):4-13. PubMed ID: 8066085
    [Abstract] [Full Text] [Related]

  • 17. Molecular modeling of the interactions of trichosanthin with four substrate analogs.
    Gu Y, Chen W, Xia Z.
    J Protein Chem; 2000 May 01; 19(4):291-7. PubMed ID: 11043934
    [Abstract] [Full Text] [Related]

  • 18. An inhibitor of c-Jun N-terminal kinases (CEP-11004) counteracts the anti-HIV-1 action of trichosanthin.
    Ouyang DY, Chan H, Wang YY, Huang H, Tam SC, Zheng YT.
    Biochem Biophys Res Commun; 2006 Jan 06; 339(1):25-9. PubMed ID: 16289100
    [Abstract] [Full Text] [Related]

  • 19. Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses.
    Chan DS, Chu LO, Lee KM, Too PH, Ma KW, Sze KH, Zhu G, Shaw PC, Wong KB.
    Nucleic Acids Res; 2007 Jan 06; 35(5):1660-72. PubMed ID: 17308345
    [Abstract] [Full Text] [Related]

  • 20. Role of Arg163 in the N-glycosidase activity of neo-trichosanthin.
    Li HG, Xu SZ, Wu S, Yan L, Li JH, Wong RN, Shi QL, Dong YC.
    Protein Eng; 1999 Nov 06; 12(11):999-1004. PubMed ID: 10585506
    [Abstract] [Full Text] [Related]

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