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557 related items for PubMed ID: 12829994

  • 1. Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice.
    Ip E, Farrell GC, Robertson G, Hall P, Kirsch R, Leclercq I.
    Hepatology; 2003 Jul; 38(1):123-32. PubMed ID: 12829994
    [Abstract] [Full Text] [Related]

  • 2. Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice.
    Ip E, Farrell G, Hall P, Robertson G, Leclercq I.
    Hepatology; 2004 May; 39(5):1286-96. PubMed ID: 15122757
    [Abstract] [Full Text] [Related]

  • 3. Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation.
    Larter CZ, Yeh MM, Cheng J, Williams J, Brown S, dela Pena A, Bell-Anderson KS, Farrell GC.
    J Gastroenterol Hepatol; 2008 Feb; 23(2):267-75. PubMed ID: 17868330
    [Abstract] [Full Text] [Related]

  • 4. Elevated basal expression of liver peroxisomal beta-oxidation enzymes and CYP4A microsomal fatty acid omega-hydroxylase in STAT5b(-/-) mice: cross-talk in vivo between peroxisome proliferator-activated receptor and signal transducer and activator of transcription signaling pathways.
    Zhou YC, Davey HW, McLachlan MJ, Xie T, Waxman DJ.
    Toxicol Appl Pharmacol; 2002 Jul 01; 182(1):1-10. PubMed ID: 12127257
    [Abstract] [Full Text] [Related]

  • 5. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis.
    Leclercq IA, Farrell GC, Field J, Bell DR, Gonzalez FJ, Robertson GR.
    J Clin Invest; 2000 Apr 01; 105(8):1067-75. PubMed ID: 10772651
    [Abstract] [Full Text] [Related]

  • 6. Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes.
    Kroetz DL, Yook P, Costet P, Bianchi P, Pineau T.
    J Biol Chem; 1998 Nov 20; 273(47):31581-9. PubMed ID: 9813074
    [Abstract] [Full Text] [Related]

  • 7. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
    Fisher CD, Jackson JP, Lickteig AJ, Augustine LM, Cherrington NJ.
    Arch Toxicol; 2008 Dec 20; 82(12):959-64. PubMed ID: 18488193
    [Abstract] [Full Text] [Related]

  • 8. Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression.
    Patsouris D, Reddy JK, Müller M, Kersten S.
    Endocrinology; 2006 Mar 20; 147(3):1508-16. PubMed ID: 16357043
    [Abstract] [Full Text] [Related]

  • 9. NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis.
    Dela Peña A, Leclercq I, Field J, George J, Jones B, Farrell G.
    Gastroenterology; 2005 Nov 20; 129(5):1663-74. PubMed ID: 16285964
    [Abstract] [Full Text] [Related]

  • 10. CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis.
    Rahman SM, Schroeder-Gloeckler JM, Janssen RC, Jiang H, Qadri I, Maclean KN, Friedman JE.
    Hepatology; 2007 May 20; 45(5):1108-17. PubMed ID: 17464987
    [Abstract] [Full Text] [Related]

  • 11. Peroxisomal and mitochondrial fatty acid beta-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor alpha and peroxisomal fatty acyl-CoA oxidase. Genotype correlation with fatty liver phenotype.
    Hashimoto T, Fujita T, Usuda N, Cook W, Qi C, Peters JM, Gonzalez FJ, Yeldandi AV, Rao MS, Reddy JK.
    J Biol Chem; 1999 Jul 02; 274(27):19228-36. PubMed ID: 10383430
    [Abstract] [Full Text] [Related]

  • 12. Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet.
    Nagasawa T, Inada Y, Nakano S, Tamura T, Takahashi T, Maruyama K, Yamazaki Y, Kuroda J, Shibata N.
    Eur J Pharmacol; 2006 Apr 24; 536(1-2):182-91. PubMed ID: 16574099
    [Abstract] [Full Text] [Related]

  • 13. Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require peroxisome proliferator-activated receptor alpha.
    Ren B, Thelen AP, Peters JM, Gonzalez FJ, Jump DB.
    J Biol Chem; 1997 Oct 24; 272(43):26827-32. PubMed ID: 9341113
    [Abstract] [Full Text] [Related]

  • 14. Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.
    Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.
    Metabolism; 2013 Nov 24; 62(11):1651-61. PubMed ID: 23928105
    [Abstract] [Full Text] [Related]

  • 15. Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis.
    Larter CZ, Yeh MM, Van Rooyen DM, Brooling J, Ghatora K, Farrell GC.
    J Gastroenterol Hepatol; 2012 Feb 24; 27(2):341-50. PubMed ID: 21929649
    [Abstract] [Full Text] [Related]

  • 16. Oxidized frying oil up-regulates hepatic acyl-CoA oxidase and cytochrome P450 4 A1 genes in rats and activates PPARalpha.
    Chao PM, Chao CY, Lin FJ, Huang C.
    J Nutr; 2001 Dec 24; 131(12):3166-74. PubMed ID: 11739861
    [Abstract] [Full Text] [Related]

  • 17. Phyllanthus urinaria ameliorates the severity of nutritional steatohepatitis both in vitro and in vivo.
    Shen B, Yu J, Wang S, Chu ES, Wong VW, Zhou X, Lin G, Sung JJ, Chan HL.
    Hepatology; 2008 Feb 24; 47(2):473-83. PubMed ID: 18157836
    [Abstract] [Full Text] [Related]

  • 18. The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis.
    Yamazaki Y, Kakizaki S, Horiguchi N, Sohara N, Sato K, Takagi H, Mori M, Negishi M.
    Gut; 2007 Apr 24; 56(4):565-74. PubMed ID: 16950832
    [Abstract] [Full Text] [Related]

  • 19. COX-2 induction in mice with experimental nutritional steatohepatitis: Role as pro-inflammatory mediator.
    Yu J, Ip E, Dela Peña A, Hou JY, Sesha J, Pera N, Hall P, Kirsch R, Leclercq I, Farrell GC.
    Hepatology; 2006 Apr 24; 43(4):826-36. PubMed ID: 16557554
    [Abstract] [Full Text] [Related]

  • 20. Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis.
    Simon Y, Kessler SM, Gemperlein K, Bohle RM, Müller R, Haybaeck J, Kiemer AK.
    World J Gastroenterol; 2014 Dec 21; 20(47):17839-50. PubMed ID: 25548482
    [Abstract] [Full Text] [Related]


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