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235 related items for PubMed ID: 12837749
1. Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C. Delisle BP, Anderson CL, Balijepalli RC, Anson BD, Kamp TJ, January CT. J Biol Chem; 2003 Sep 12; 278(37):35749-54. PubMed ID: 12837749 [Abstract] [Full Text] [Related]
2. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations. Ficker E, Obejero-Paz CA, Zhao S, Brown AM. J Biol Chem; 2002 Feb 15; 277(7):4989-98. PubMed ID: 11741928 [Abstract] [Full Text] [Related]
5. Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-à-go-go-Related Gene. Roti EC, Myers CD, Ayers RA, Boatman DE, Delfosse SA, Chan EK, Ackerman MJ, January CT, Robertson GA. J Biol Chem; 2002 Dec 06; 277(49):47779-85. PubMed ID: 12270925 [Abstract] [Full Text] [Related]
7. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel. Furutani M, Trudeau MC, Hagiwara N, Seki A, Gong Q, Zhou Z, Imamura S, Nagashima H, Kasanuki H, Takao A, Momma K, January CT, Robertson GA, Matsuoka R. Circulation; 1999 May 04; 99(17):2290-4. PubMed ID: 10226095 [Abstract] [Full Text] [Related]
8. Intragenic suppression of trafficking-defective KCNH2 channels associated with long QT syndrome. Delisle BP, Slind JK, Kilby JA, Anderson CL, Anson BD, Balijepalli RC, Tester DJ, Ackerman MJ, Kamp TJ, January CT. Mol Pharmacol; 2005 Jul 04; 68(1):233-40. PubMed ID: 15851652 [Abstract] [Full Text] [Related]
10. Defective human Ether-à-go-go-related gene trafficking linked to an endoplasmic reticulum retention signal in the C terminus. Kupershmidt S, Yang T, Chanthaphaychith S, Wang Z, Towbin JA, Roden DM. J Biol Chem; 2002 Jul 26; 277(30):27442-8. PubMed ID: 12021266 [Abstract] [Full Text] [Related]
11. Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits. Gong Q, Anderson CL, January CT, Zhou Z. Am J Physiol Heart Circ Physiol; 2004 Aug 26; 287(2):H652-8. PubMed ID: 15072950 [Abstract] [Full Text] [Related]
17. Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing. Thomas D, Kiehn J, Katus HA, Karle CA. Cardiovasc Res; 2003 Nov 01; 60(2):235-41. PubMed ID: 14613852 [Abstract] [Full Text] [Related]
18. Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome. Ficker E, Dennis AT, Obejero-Paz CA, Castaldo P, Taglialatela M, Brown AM. J Mol Cell Cardiol; 2000 Dec 01; 32(12):2327-37. PubMed ID: 11113008 [Abstract] [Full Text] [Related]
19. HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects. Zhou Z, Gong Q, Epstein ML, January CT. J Biol Chem; 1998 Aug 14; 273(33):21061-6. PubMed ID: 9694858 [Abstract] [Full Text] [Related]
20. Molecular determinants of dofetilide block of HERG K+ channels. Ficker E, Jarolimek W, Kiehn J, Baumann A, Brown AM. Circ Res; 1998 Feb 23; 82(3):386-95. PubMed ID: 9486667 [Abstract] [Full Text] [Related] Page: [Next] [New Search]