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Journal Abstract Search

217 related items for PubMed ID: 12839864

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  • 2. Lipid-lowering effects of TAK-475, a squalene synthase inhibitor, in animal models of familial hypercholesterolemia.
    Amano Y, Nishimoto T, Tozawa Ri, Ishikawa E, Imura Y, Sugiyama Y.
    Eur J Pharmacol; 2003 Apr 11; 466(1-2):155-61. PubMed ID: 12679152
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  • 4. Pharmacological characterization in vitro of EP2306 and EP2302, potent inhibitors of squalene synthase and lipid biosynthesis.
    Tavridou A, Kaklamanis L, Megaritis G, Kourounakis AP, Papalois A, Roukounas D, Rekka EA, Kourounakis PN, Charalambous A, Manolopoulos VG.
    Eur J Pharmacol; 2006 Mar 27; 535(1-3):34-42. PubMed ID: 16545796
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  • 8. Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs.
    Nishimoto T, Ishikawa E, Anayama H, Hamajyo H, Nagai H, Hirakata M, Tozawa R.
    Toxicol Appl Pharmacol; 2007 Aug 15; 223(1):39-45. PubMed ID: 17599378
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  • 11. Synthesis of novel 4,1-benzoxazepine derivatives as squalene synthase inhibitors and their inhibition of cholesterol synthesis.
    Miki T, Kori M, Mabuchi H, Tozawa R, Nishimoto T, Sugiyama Y, Teshima K, Yukimasa H.
    J Med Chem; 2002 Sep 26; 45(20):4571-80. PubMed ID: 12238936
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  • 14. Squalene synthase inhibition: a novel target for the management of dyslipidemia.
    Davidson MH.
    Curr Atheroscler Rep; 2007 Jan 26; 9(1):78-80. PubMed ID: 17169251
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  • 20. Synthesis and biological evaluation of novel propylamine derivatives as orally active squalene synthase inhibitors.
    Ishihara T, Kakuta H, Moritani H, Ugawa T, Yanagisawa I.
    Bioorg Med Chem; 2004 Nov 15; 12(22):5899-908. PubMed ID: 15498666
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