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Journal Abstract Search

132 related items for PubMed ID: 12851038

  • 1. In vitro inhibition of human small intestinal and liver microsomal astemizole O-demethylation: different contribution of CYP2J2 in the small intestine and liver.
    Matsumoto S, Hirama T, Kim HJ, Nagata K, Yamazoe Y.
    Xenobiotica; 2003 Jun; 33(6):615-23. PubMed ID: 12851038
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  • 2. Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole.
    Matsumoto S, Hirama T, Matsubara T, Nagata K, Yamazoe Y.
    Drug Metab Dispos; 2002 Nov; 30(11):1240-5. PubMed ID: 12386130
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  • 3. Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Lee CA, Jones JP, Katayama J, Kaspera R, Jiang Y, Freiwald S, Smith E, Walker GS, Totah RA.
    Drug Metab Dispos; 2012 May; 40(5):943-51. PubMed ID: 22328583
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  • 5. Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine.
    Matsumoto S, Yamazoe Y.
    Br J Clin Pharmacol; 2001 Feb; 51(2):133-42. PubMed ID: 11259984
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  • 6. Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism.
    Fitzsimmons ME, Collins JM.
    Drug Metab Dispos; 1997 Feb; 25(2):256-66. PubMed ID: 9029057
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  • 7. Marmoset cytochrome P450 2J2 mainly expressed in small intestines and livers effectively metabolizes human P450 2J2 probe substrates, astemizole and terfenadine.
    Uehara S, Uno Y, Inoue T, Okamoto E, Sasaki E, Yamazaki H.
    Xenobiotica; 2016 Nov; 46(11):977-85. PubMed ID: 26899760
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  • 10. Terfenadone is a strong inhibitor of CYP2J2 present in the human liver and intestinal microsomes.
    Lee E, Kim JH, Shon JC, Wu Z, Kim HJ, Gim M, Lee T, Liu KH.
    Drug Metab Pharmacokinet; 2018 Jun; 33(3):159-163. PubMed ID: 29759885
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  • 12. The inhibitory potential of Broussochalcone A for the human cytochrome P450 2J2 isoform and its anti-cancer effects via FOXO3 activation.
    Park SH, Lee J, Shon JC, Phuc NM, Jee JG, Liu KH.
    Phytomedicine; 2018 Mar 15; 42():199-206. PubMed ID: 29655687
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  • 13. Identification of novel substrates for human cytochrome P450 2J2.
    Lee CA, Neul D, Clouser-Roche A, Dalvie D, Wester MR, Jiang Y, Jones JP, Freiwald S, Zientek M, Totah RA.
    Drug Metab Dispos; 2010 Feb 15; 38(2):347-56. PubMed ID: 19923256
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  • 14. Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability.
    Lampen A, Christians U, Guengerich FP, Watkins PB, Kolars JC, Bader A, Gonschior AK, Dralle H, Hackbarth I, Sewing KF.
    Drug Metab Dispos; 1995 Dec 15; 23(12):1315-24. PubMed ID: 8689938
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  • 15. Metabolism of epinastine, a histamine H1 receptor antagonist, in human liver microsomes in comparison with that of terfenadine.
    Kishimoto W, Hiroi T, Sakai K, Funae Y, Igarashi T.
    Res Commun Mol Pathol Pharmacol; 1997 Dec 15; 98(3):273-92. PubMed ID: 9485522
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