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317 related items for PubMed ID: 12857935

  • 1. Hyperforin contributes to the hepatic CYP3A-inducing effect of Hypericum perforatum extract in the mouse.
    Cantoni L, Rozio M, Mangolini A, Hauri L, Caccia S.
    Toxicol Sci; 2003 Sep; 75(1):25-30. PubMed ID: 12857935
    [Abstract] [Full Text] [Related]

  • 2. Step by step removal of hyperforin and hypericin: activity profile of different Hypericum preparations in behavioral models.
    Butterweck V, Christoffel V, Nahrstedt A, Petereit F, Spengler B, Winterhoff H.
    Life Sci; 2003 Jun 20; 73(5):627-39. PubMed ID: 12770617
    [Abstract] [Full Text] [Related]

  • 3. The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose.
    Mueller SC, Majcher-Peszynska J, Uehleke B, Klammt S, Mundkowski RG, Miekisch W, Sievers H, Bauer S, Frank B, Kundt G, Drewelow B.
    Eur J Clin Pharmacol; 2006 Jan 20; 62(1):29-36. PubMed ID: 16341856
    [Abstract] [Full Text] [Related]

  • 4. Effect of the St. John's wort constituent hyperforin on docetaxel metabolism by human hepatocyte cultures.
    Komoroski BJ, Parise RA, Egorin MJ, Strom SC, Venkataramanan R.
    Clin Cancer Res; 2005 Oct 01; 11(19 Pt 1):6972-9. PubMed ID: 16203790
    [Abstract] [Full Text] [Related]

  • 5. St John's wort, a herbal antidepressant, activates the steroid X receptor.
    Wentworth JM, Agostini M, Love J, Schwabe JW, Chatterjee VK.
    J Endocrinol; 2000 Sep 01; 166(3):R11-6. PubMed ID: 10974665
    [Abstract] [Full Text] [Related]

  • 6. Correlation of hyperforin content of Hypericum perforatum (St John's Wort) extracts with their effects on alcohol drinking in C57BL/6J mice: a preliminary study.
    Wright CW, Gott M, Grayson B, Hanna M, Smith AG, Sunter A, Neill JC.
    J Psychopharmacol; 2003 Dec 01; 17(4):403-8. PubMed ID: 14870952
    [Abstract] [Full Text] [Related]

  • 7. The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity.
    Wang Z, Gorski JC, Hamman MA, Huang SM, Lesko LJ, Hall SD.
    Clin Pharmacol Ther; 2001 Oct 01; 70(4):317-26. PubMed ID: 11673747
    [Abstract] [Full Text] [Related]

  • 8. Variability in PXR-mediated induction of CYP3A4 by commercial preparations and dry extracts of St. John's wort.
    Gödtel-Armbrust U, Metzger A, Kroll U, Kelber O, Wojnowski L.
    Naunyn Schmiedebergs Arch Pharmacol; 2007 Aug 01; 375(6):377-82. PubMed ID: 17593354
    [Abstract] [Full Text] [Related]

  • 9. Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures.
    Komoroski BJ, Zhang S, Cai H, Hutzler JM, Frye R, Tracy TS, Strom SC, Lehmann T, Ang CY, Cui YY, Venkataramanan R.
    Drug Metab Dispos; 2004 May 01; 32(5):512-8. PubMed ID: 15100173
    [Abstract] [Full Text] [Related]

  • 10. No clinically relevant CYP3A induction after St. John's wort with low hyperforin content in healthy volunteers.
    Mueller SC, Majcher-Peszynska J, Mundkowski RG, Uehleke B, Klammt S, Sievers H, Lehnfeld R, Frank B, Thurow K, Kundt G, Drewelow B.
    Eur J Clin Pharmacol; 2009 Jan 01; 65(1):81-7. PubMed ID: 18762932
    [Abstract] [Full Text] [Related]

  • 11. St. John's wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse.
    Bray BJ, Perry NB, Menkes DB, Rosengren RJ.
    Toxicol Sci; 2002 Mar 01; 66(1):27-33. PubMed ID: 11861970
    [Abstract] [Full Text] [Related]

  • 12. Hyperforin in St. John's wort drug interactions.
    Madabushi R, Frank B, Drewelow B, Derendorf H, Butterweck V.
    Eur J Clin Pharmacol; 2006 Mar 01; 62(3):225-33. PubMed ID: 16477470
    [Abstract] [Full Text] [Related]

  • 13. In vitro effects of the dicyclohexylammonium salt of hyperforin on interleukin-6 release in different experimental models.
    Gobbi M, Moia M, Funicello M, Riva A, Morazzoni P, Mennini T.
    Planta Med; 2004 Jul 01; 70(7):680-2. PubMed ID: 15303261
    [Abstract] [Full Text] [Related]

  • 14. Understanding drug interactions with St John's wort (Hypericum perforatum L.): impact of hyperforin content.
    Chrubasik-Hausmann S, Vlachojannis J, McLachlan AJ.
    J Pharm Pharmacol; 2019 Jan 01; 71(1):129-138. PubMed ID: 29411879
    [Abstract] [Full Text] [Related]

  • 15. Role of hyperforin in the antidepressant-like activity of Hypericum perforatum extracts.
    Cervo L, Rozio M, Ekalle-Soppo CB, Guiso G, Morazzoni P, Caccia S.
    Psychopharmacology (Berl); 2002 Dec 01; 164(4):423-8. PubMed ID: 12457273
    [Abstract] [Full Text] [Related]

  • 16. Antidepressant activity of hyperforin conjugates of the St. John's wort, Hypericum perforatum Linn.: an experimental study.
    Muruganandam AV, Bhattacharya SK, Ghosal S.
    Indian J Exp Biol; 2001 Dec 01; 39(12):1302-4. PubMed ID: 12018529
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of hyperforin, the active constituent of St. John's wort, in human liver microsomes.
    Hokkanen J, Tolonen A, Mattila S, Turpeinen M.
    Eur J Pharm Sci; 2011 Feb 14; 42(3):273-84. PubMed ID: 21168483
    [Abstract] [Full Text] [Related]

  • 18. The time-dependent effects of St John's wort on cytochrome P450, uridine diphosphate-glucuronosyltransferase, glutathione S-transferase, and NAD(P)H-quinone oxidoreductase in mice.
    Yang JF, Liu YR, Huang CC, Ueng YF.
    J Food Drug Anal; 2018 Jan 14; 26(1):422-431. PubMed ID: 29389584
    [Abstract] [Full Text] [Related]

  • 19. Effects of a methanolic extract and a hyperforin-enriched CO2 extract of St. John's Wort (Hypericum perforatum) on intracerebral field potentials in the freely moving rat (Tele-Stereo-EEG).
    Dimpfel W, Schober F, Mannel M.
    Pharmacopsychiatry; 1998 Jun 14; 31 Suppl 1():30-5. PubMed ID: 9684945
    [Abstract] [Full Text] [Related]

  • 20. Protective effects of St. John's wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line.
    Menegazzi M, Novelli M, Beffy P, D'Aleo V, Tedeschi E, Lupi R, Zoratti E, Marchetti P, Suzuki H, Masiello P.
    Int J Biochem Cell Biol; 2008 Jun 14; 40(8):1509-21. PubMed ID: 18226577
    [Abstract] [Full Text] [Related]

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