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Journal Abstract Search

231 related items for PubMed ID: 12869732

  • 1. Medicine. Drug deals diabetes a one-two punch.
    Couzin J.
    Science; 2003 Jul 18; 301(5631):290. PubMed ID: 12869732
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  • 2. Allosteric activators of glucokinase: potential role in diabetes therapy.
    Grimsby J, Sarabu R, Corbett WL, Haynes NE, Bizzarro FT, Coffey JW, Guertin KR, Hilliard DW, Kester RF, Mahaney PE, Marcus L, Qi L, Spence CL, Tengi J, Magnuson MA, Chu CA, Dvorozniak MT, Matschinsky FM, Grippo JF.
    Science; 2003 Jul 18; 301(5631):370-3. PubMed ID: 12869762
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  • 4. Discovery of 3-(4-methanesulfonylphenoxy)-N-[1-(2-methoxy-ethoxymethyl)-1H-pyrazol-3-yl]-5-(3-methylpyridin-2-yl)-benzamide as a novel glucokinase activator (GKA) for the treatment of type 2 diabetes mellitus.
    Park K, Lee BM, Hyun KH, Lee DH, Choi HH, Kim H, Chong W, Kim KB, Nam SY.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2280-93. PubMed ID: 24588963
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  • 5. Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus.
    Xu J, Lin S, Myers RW, Addona G, Berger JP, Campbell B, Chen HS, Chen Z, Eiermann GJ, Elowe NH, Farrer BT, Feng W, Fu Q, Kats-Kagan R, Kavana M, Malkani S, McMasters DR, Mitra K, Pachanski MJ, Tong X, Trujillo ME, Xu L, Zhang B, Zhang F, Zhang R, Parmee ER.
    Bioorg Med Chem Lett; 2017 May 01; 27(9):2069-2073. PubMed ID: 28284804
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  • 7. Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus.
    Xu J, Lin S, Myers RW, Trujillo ME, Pachanski MJ, Malkani S, Chen HS, Chen Z, Campbell B, Eiermann GJ, Elowe N, Farrer BT, Feng W, Fu Q, Kats-Kagan R, Kavana M, McMasters DR, Mitra K, Tong X, Xu L, Zhang F, Zhang R, Addona GH, Berger JP, Zhang B, Parmee ER.
    Bioorg Med Chem Lett; 2017 May 01; 27(9):2063-2068. PubMed ID: 28284809
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  • 9. A novel glucokinase activator modulates pancreatic islet and hepatocyte function.
    Efanov AM, Barrett DG, Brenner MB, Briggs SL, Delaunois A, Durbin JD, Giese U, Guo H, Radloff M, Gil GS, Sewing S, Wang Y, Weichert A, Zaliani A, Gromada J.
    Endocrinology; 2005 Sep 01; 146(9):3696-701. PubMed ID: 15919746
    [Abstract] [Full Text] [Related]

  • 10. Identification of mangiferin as a potential Glucokinase activator by structure-based virtual ligand screening.
    Min Q, Cai X, Sun W, Gao F, Li Z, Zhang Q, Wan LS, Li H, Chen J.
    Sci Rep; 2017 Mar 20; 7():44681. PubMed ID: 28317897
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  • 11. Recent advances in glucokinase activators for the treatment of type 2 diabetes.
    Pal M.
    Drug Discov Today; 2009 Aug 20; 14(15-16):784-92. PubMed ID: 19520181
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  • 13. Treatment with exendin-4 improves the antidiabetic efficacy and reverses hepatic steatosis in glucokinase activator treated db/db mice.
    Dhanesha N, Joharapurkar A, Shah G, Kshirsagar S, Patel V, Patel K, Bahekar R, Jain M.
    Eur J Pharmacol; 2013 Aug 15; 714(1-3):188-92. PubMed ID: 23810686
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  • 15. Discovery of liver-directed glucokinase activator having anti-hyperglycemic effect without hypoglycemia.
    Deshpande AM, Bhuniya D, De S, Dave B, Vyavahare VP, Kurhade SH, Kandalkar SR, Naik KP, Kobal BS, Kaduskar RD, Basu S, Jain V, Patil P, Chaturvedi Joshi S, Bhat G, Raje AA, Reddy S, Gundu J, Madgula V, Tambe S, Shitole P, Umrani D, Chugh A, Palle VP, Mookhtiar KA.
    Eur J Med Chem; 2017 Jun 16; 133():268-286. PubMed ID: 28390958
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  • 17. Effect of 1-[4- [2-(4-bromobenzenesulfonamino) ethyl] phenylsulfonyl]-3-(trans-4-methylcyclohexyl)urea (I4), a new synthetic sulfonylurea compound, on glucose metabolism in vivo and in vitro.
    Wu GZ, Hong G, Zhang WP, Zhang HB.
    Arzneimittelforschung; 2009 Jun 16; 59(11):550-6. PubMed ID: 20066963
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