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422 related items for PubMed ID: 12874002

  • 1. A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines.
    Brandi G, Paiardini M, Cervasi B, Fiorucci C, Filippone P, De Marco C, Zaffaroni N, Magnani M.
    Cancer Res; 2003 Jul 15; 63(14):4028-36. PubMed ID: 12874002
    [Abstract] [Full Text] [Related]

  • 2. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells.
    Chinni SR, Li Y, Upadhyay S, Koppolu PK, Sarkar FH.
    Oncogene; 2001 May 24; 20(23):2927-36. PubMed ID: 11420705
    [Abstract] [Full Text] [Related]

  • 3. Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells.
    Cover CM, Hsieh SJ, Cram EJ, Hong C, Riby JE, Bjeldanes LF, Firestone GL.
    Cancer Res; 1999 Mar 15; 59(6):1244-51. PubMed ID: 10096555
    [Abstract] [Full Text] [Related]

  • 4. Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.
    Cover CM, Hsieh SJ, Tran SH, Hallden G, Kim GS, Bjeldanes LF, Firestone GL.
    J Biol Chem; 1998 Feb 13; 273(7):3838-47. PubMed ID: 9461564
    [Abstract] [Full Text] [Related]

  • 5. Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells.
    Zhang J, Hsu B A JC, Kinseth B A MA, Bjeldanes LF, Firestone GL.
    Cancer; 2003 Dec 01; 98(11):2511-20. PubMed ID: 14635088
    [Abstract] [Full Text] [Related]

  • 6. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.
    Carlson BA, Dubay MM, Sausville EA, Brizuela L, Worland PJ.
    Cancer Res; 1996 Jul 01; 56(13):2973-8. PubMed ID: 8674031
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate.
    Liang YC, Lin-Shiau SY, Chen CF, Lin JK.
    J Cell Biochem; 1999 Oct 01; 75(1):1-12. PubMed ID: 10462699
    [Abstract] [Full Text] [Related]

  • 8. Insulin-like growth factor binding protein-3 induces G1 cell cycle arrest with inhibition of cyclin-dependent kinase 2 and 4 in MCF-7 human breast cancer cells.
    Kim HS, Lee WJ, Lee SW, Chae HW, Kim DH, Oh Y.
    Horm Metab Res; 2010 Mar 01; 42(3):165-72. PubMed ID: 19960406
    [Abstract] [Full Text] [Related]

  • 9. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S, Lowe M, Herliczek TW, Keyomarsi K.
    Oncogene; 1998 Nov 05; 17(18):2393-402. PubMed ID: 9811471
    [Abstract] [Full Text] [Related]

  • 10. Translocation of Bax to mitochondria induces apoptotic cell death in indole-3-carbinol (I3C) treated breast cancer cells.
    Rahman KM, Aranha O, Glazyrin A, Chinni SR, Sarkar FH.
    Oncogene; 2000 Nov 23; 19(50):5764-71. PubMed ID: 11126363
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.
    Srethapakdi M, Liu F, Tavorath R, Rosen N.
    Cancer Res; 2000 Jul 15; 60(14):3940-6. PubMed ID: 10919672
    [Abstract] [Full Text] [Related]

  • 12. The role of p27Kip1 in gamma interferon-mediated growth arrest of mammary epithelial cells and related defects in mammary carcinoma cells.
    Harvat BL, Seth P, Jetten AM.
    Oncogene; 1997 May 01; 14(17):2111-22. PubMed ID: 9160891
    [Abstract] [Full Text] [Related]

  • 13. Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.
    Damiens E, El Yazidi I, Mazurier J, Duthille I, Spik G, Boilly-Marer Y.
    J Cell Biochem; 1999 Sep 01; 74(3):486-98. PubMed ID: 10412049
    [Abstract] [Full Text] [Related]

  • 14. Indole-3-carbinol activates the cyclin-dependent kinase inhibitor p15(INK4b) gene.
    Matsuzaki Y, Koyama M, Hitomi T, Kawanaka M, Sakai T.
    FEBS Lett; 2004 Oct 08; 576(1-2):137-40. PubMed ID: 15474025
    [Abstract] [Full Text] [Related]

  • 15. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 08; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

  • 16. AP-1 blockade in breast cancer cells causes cell cycle arrest by suppressing G1 cyclin expression and reducing cyclin-dependent kinase activity.
    Liu Y, Lu C, Shen Q, Munoz-Medellin D, Kim H, Brown PH.
    Oncogene; 2004 Oct 28; 23(50):8238-46. PubMed ID: 15378019
    [Abstract] [Full Text] [Related]

  • 17. Involvement of G1/S cyclins in estrogen-independent proliferation of estrogen receptor-positive breast cancer cells.
    Bindels EM, Lallemand F, Balkenende A, Verwoerd D, Michalides R.
    Oncogene; 2002 Nov 21; 21(53):8158-65. PubMed ID: 12444551
    [Abstract] [Full Text] [Related]

  • 18. Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
    Aronchik I, Chen T, Durkin KA, Horwitz MS, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL.
    Mol Carcinog; 2012 Nov 21; 51(11):881-94. PubMed ID: 22012859
    [Abstract] [Full Text] [Related]

  • 19. Tamoxifen induces p21WAF1 and p27KIP1 expression in estrogen receptor-negative lung cancer cells.
    Lee TH, Chuang LY, Hung WC.
    Oncogene; 1999 Jul 22; 18(29):4269-74. PubMed ID: 10435640
    [Abstract] [Full Text] [Related]

  • 20. Characterization of the N-methoxyindole-3-carbinol (NI3C)--induced cell cycle arrest in human colon cancer cell lines.
    Neave AS, Sarup SM, Seidelin M, Duus F, Vang O.
    Toxicol Sci; 2005 Jan 22; 83(1):126-35. PubMed ID: 15483186
    [Abstract] [Full Text] [Related]

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