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PUBMED FOR HANDHELDS

Journal Abstract Search


168 related items for PubMed ID: 12874004

  • 1. Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells.
    Shingu T, Yamada K, Hara N, Moritake K, Osago H, Terashima M, Uemura T, Yamasaki T, Tsuchiya M.
    Cancer Res; 2003 Jul 15; 63(14):4044-7. PubMed ID: 12874004
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  • 2. Phosphatidylinositol 3-kinases inhibitor LY294002 potentiates the cytotoxic effects of doxorubicin, vincristine, and etoposide in a panel of cancer cell lines.
    Badinloo M, Esmaeili-Mahani S.
    Fundam Clin Pharmacol; 2014 Aug 15; 28(4):414-22. PubMed ID: 23837575
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  • 3. Growth inhibition of human malignant glioma cells induced by the PI3-K-specific inhibitor.
    Shingu T, Yamada K, Hara N, Moritake K, Osago H, Terashima M, Uemura T, Yamasaki T, Tsuchiya M.
    J Neurosurg; 2003 Jan 15; 98(1):154-61. PubMed ID: 12546364
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  • 7. Cotreatment with a novel phosphoinositide analogue inhibitor and carmustine enhances chemotherapeutic efficacy by attenuating AKT activity in gliomas.
    Van Meter TE, Broaddus WC, Cash D, Fillmore H.
    Cancer; 2006 Nov 15; 107(10):2446-54. PubMed ID: 17041888
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  • 11. Combinatorial therapy with adenoviral-mediated PTEN and a PI3K inhibitor suppresses malignant glioma cell growth in vitro and in vivo by regulating the PI3K/AKT signaling pathway.
    Nan Y, Guo L, Song Y, Wang L, Yu K, Huang Q, Zhong Y.
    J Cancer Res Clin Oncol; 2017 Aug 15; 143(8):1477-1487. PubMed ID: 28401302
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  • 12. LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway.
    Poh TW, Pervaiz S.
    Cancer Res; 2005 Jul 15; 65(14):6264-74. PubMed ID: 16024628
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  • 13. LY294002 enhances cytotoxicity of temozolomide in glioma by down-regulation of the PI3K/Akt pathway.
    Chen L, Han L, Shi Z, Zhang K, Liu Y, Zheng Y, Jiang T, Pu P, Jiang C, Kang C.
    Mol Med Rep; 2012 Feb 15; 5(2):575-9. PubMed ID: 22086271
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  • 14. Modulation of DNA repair in vitro after treatment with chemotherapeutic agents by the epidermal growth factor receptor inhibitor gefitinib (ZD1839).
    Friedmann B, Caplin M, Hartley JA, Hochhauser D.
    Clin Cancer Res; 2004 Oct 01; 10(19):6476-86. PubMed ID: 15475435
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  • 15. Blockade of the phosphatidylinositol-3-kinase-Akt signaling pathway enhances the induction of apoptosis by microtubule-destabilizing agents in tumor cells in which the pathway is constitutively activated.
    Fujiwara Y, Hosokawa Y, Watanabe K, Tanimura S, Ozaki K, Kohno M.
    Mol Cancer Ther; 2007 Mar 01; 6(3):1133-42. PubMed ID: 17363506
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  • 17. GSK-3beta reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis.
    Beurel E, Kornprobst M, Blivet-Van Eggelpoël MJ, Cadoret A, Capeau J, Desbois-Mouthon C.
    Int J Oncol; 2005 Jul 01; 27(1):215-22. PubMed ID: 15942663
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  • 19. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C, Rahmani M, Dai Y, Conrad D, Krystal G, Dent P, Grant S.
    Cancer Res; 2003 Apr 15; 63(8):1822-33. PubMed ID: 12702569
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  • 20. Modulating effect of the PI3-kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells.
    Fujiwara M, Izuishi K, Sano T, Hossain MA, Kimura S, Masaki T, Suzuki Y.
    J Exp Clin Cancer Res; 2008 Nov 25; 27(1):76. PubMed ID: 19032736
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