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921 related items for PubMed ID: 12876289

  • 1. Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
    Song K, Cornelius SC, Reiss M, Danielpour D.
    J Biol Chem; 2003 Oct 03; 278(40):38342-51. PubMed ID: 12876289
    [Abstract] [Full Text] [Related]

  • 2. The phosphatidylinositol 3-kinase/Akt pathway enhances Smad3-stimulated mesangial cell collagen I expression in response to transforming growth factor-beta1.
    Runyan CE, Schnaper HW, Poncelet AC.
    J Biol Chem; 2004 Jan 23; 279(4):2632-9. PubMed ID: 14610066
    [Abstract] [Full Text] [Related]

  • 3. Critical role of a survivin/TGF-β/mTORC1 axis in IGF-I-mediated growth of prostate epithelial cells.
    Song K, Shankar E, Yang J, Bane KL, Wahdan-Alaswad R, Danielpour D.
    PLoS One; 2013 Jan 23; 8(5):e61896. PubMed ID: 23658701
    [Abstract] [Full Text] [Related]

  • 4. The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells.
    Poncelet AC, de Caestecker MP, Schnaper HW.
    Kidney Int; 1999 Oct 23; 56(4):1354-65. PubMed ID: 10504488
    [Abstract] [Full Text] [Related]

  • 5. The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.
    Chipuk JE, Cornelius SC, Pultz NJ, Jorgensen JS, Bonham MJ, Kim SJ, Danielpour D.
    J Biol Chem; 2002 Jan 11; 277(2):1240-8. PubMed ID: 11707452
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  • 9. IGF-binding proteins mediate TGF-beta 1-induced apoptosis in bovine mammary epithelial BME-UV1 cells.
    Gajewska M, Motyl T.
    Comp Biochem Physiol C Toxicol Pharmacol; 2004 Oct 11; 139(1-3):65-75. PubMed ID: 15556067
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  • 10. Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity.
    Hjelmeland AB, Hjelmeland MD, Shi Q, Hart JL, Bigner DD, Wang XF, Kontos CD, Rich JN.
    Cancer Res; 2005 Dec 15; 65(24):11276-81. PubMed ID: 16357132
    [Abstract] [Full Text] [Related]

  • 11. Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
    Zhang D, Bar-Eli M, Meloche S, Brodt P.
    J Biol Chem; 2004 May 07; 279(19):19683-90. PubMed ID: 14993222
    [Abstract] [Full Text] [Related]

  • 12. Transforming growth factor-beta inhibition of insulin-like growth factor-binding protein-5 synthesis in skeletal muscle cells involves a c-Jun N-terminal kinase-dependent pathway.
    Rousse S, Lallemand F, Montarras D, Pinset C, Mazars A, Prunier C, Atfi A, Dubois C.
    J Biol Chem; 2001 Dec 14; 276(50):46961-7. PubMed ID: 11598109
    [Abstract] [Full Text] [Related]

  • 13. Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.
    Qiao M, Shapiro P, Kumar R, Passaniti A.
    J Biol Chem; 2004 Oct 08; 279(41):42709-18. PubMed ID: 15304489
    [Abstract] [Full Text] [Related]

  • 14. Activated phosphatidylinositol 3-kinase/Akt inhibits the transition of endothelial progenitor cells to mesenchymal cells by regulating the forkhead box subgroup O-3a signaling.
    Zhang Z, Zhang T, Zhou Y, Wei X, Zhu J, Zhang J, Wang C.
    Cell Physiol Biochem; 2015 Oct 08; 35(4):1643-53. PubMed ID: 25824462
    [Abstract] [Full Text] [Related]

  • 15. Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells.
    Zheng WH, Kar S, Quirion R.
    J Biol Chem; 2000 Dec 15; 275(50):39152-8. PubMed ID: 10995739
    [Abstract] [Full Text] [Related]

  • 16. Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer.
    Cui X, Zhang P, Deng W, Oesterreich S, Lu Y, Mills GB, Lee AV.
    Mol Endocrinol; 2003 Apr 15; 17(4):575-88. PubMed ID: 12554765
    [Abstract] [Full Text] [Related]

  • 17. Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha.
    Phillips RJ, Mestas J, Gharaee-Kermani M, Burdick MD, Sica A, Belperio JA, Keane MP, Strieter RM.
    J Biol Chem; 2005 Jun 10; 280(23):22473-81. PubMed ID: 15802268
    [Abstract] [Full Text] [Related]

  • 18. The murine gastrin promoter is synergistically activated by transforming growth factor-beta/Smad and Wnt signaling pathways.
    Lei S, Dubeykovskiy A, Chakladar A, Wojtukiewicz L, Wang TC.
    J Biol Chem; 2004 Oct 08; 279(41):42492-502. PubMed ID: 15292219
    [Abstract] [Full Text] [Related]

  • 19. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ.
    Cancer Res; 2003 Jan 15; 63(2):364-74. PubMed ID: 12543789
    [Abstract] [Full Text] [Related]

  • 20. Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells.
    Poncelet AC, Schnaper HW.
    J Biol Chem; 2001 Mar 09; 276(10):6983-92. PubMed ID: 11114293
    [Abstract] [Full Text] [Related]

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