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161 related items for PubMed ID: 12884365

  • 1. Pifithrin-alpha promotes p53-mediated apoptosis in JB6 cells.
    Kaji A, Zhang Y, Nomura M, Bode AM, Ma WY, She QB, Dong Z.
    Mol Carcinog; 2003 Jul; 37(3):138-48. PubMed ID: 12884365
    [Abstract] [Full Text] [Related]

  • 2. Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation.
    Wang J, Ouyang W, Li J, Wei L, Ma Q, Zhang Z, Tong Q, He J, Huang C.
    Cancer Res; 2005 Aug 01; 65(15):6601-11. PubMed ID: 16061640
    [Abstract] [Full Text] [Related]

  • 3. Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation.
    Murphy PJ, Galigniana MD, Morishima Y, Harrell JM, Kwok RP, Ljungman M, Pratt WB.
    J Biol Chem; 2004 Jul 16; 279(29):30195-201. PubMed ID: 15145929
    [Abstract] [Full Text] [Related]

  • 4. Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase.
    She QB, Bode AM, Ma WY, Chen NY, Dong Z.
    Cancer Res; 2001 Feb 15; 61(4):1604-10. PubMed ID: 11245472
    [Abstract] [Full Text] [Related]

  • 5. p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways.
    Komarova EA, Neznanov N, Komarov PG, Chernov MV, Wang K, Gudkov AV.
    J Biol Chem; 2003 May 02; 278(18):15465-8. PubMed ID: 12637507
    [Abstract] [Full Text] [Related]

  • 6. Role of MAP kinases in UVB-induced phosphorylation of p53 at serine 20.
    She QB, Ma WY, Dong Z.
    Oncogene; 2002 Feb 28; 21(10):1580-9. PubMed ID: 11896587
    [Abstract] [Full Text] [Related]

  • 7. Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells.
    Chua CC, Liu X, Gao J, Hamdy RC, Chua BH.
    Am J Physiol Heart Circ Physiol; 2006 Jun 28; 290(6):H2606-13. PubMed ID: 16687611
    [Abstract] [Full Text] [Related]

  • 8. Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis.
    Tamagno E, Parola M, Guglielmotto M, Santoro G, Bardini P, Marra L, Tabaton M, Danni O.
    Free Radic Biol Med; 2003 Jul 01; 35(1):45-58. PubMed ID: 12826255
    [Abstract] [Full Text] [Related]

  • 9. UVB-mediated activation of p38 mitogen-activated protein kinase enhances resistance of normal human keratinocytes to apoptosis by stabilizing cytoplasmic p53.
    Chouinard N, Valerie K, Rouabhia M, Huot J.
    Biochem J; 2002 Jul 01; 365(Pt 1):133-45. PubMed ID: 12071847
    [Abstract] [Full Text] [Related]

  • 10. MAPK inhibitors and pifithrin-alpha block cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells.
    Wu SJ, Ng LT.
    Food Chem Toxicol; 2007 Dec 01; 45(12):2446-53. PubMed ID: 17673346
    [Abstract] [Full Text] [Related]

  • 11. Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha.
    Sparfel L, Van Grevenynghe J, Le Vee M, Aninat C, Fardel O.
    Carcinogenesis; 2006 Mar 01; 27(3):656-63. PubMed ID: 16258175
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of p53, p21 and Bax by pifithrin-alpha does not affect UV induced apoptotic response in CS-B cells.
    Proietti De Santis L, Balajee AS, Lorenti Garcia C, Pepe G, Worboys AM, Palitti F.
    DNA Repair (Amst); 2003 Aug 12; 2(8):891-900. PubMed ID: 12893085
    [Abstract] [Full Text] [Related]

  • 13. [PFTalpha, guardian of the sick?].
    Jacquemin-Sablon A.
    Bull Cancer; 1999 Nov 12; 86(11):894-5. PubMed ID: 10627130
    [No Abstract] [Full Text] [Related]

  • 14. An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines.
    Walton MI, Wilson SC, Hardcastle IR, Mirza AR, Workman P.
    Mol Cancer Ther; 2005 Sep 12; 4(9):1369-77. PubMed ID: 16170029
    [Abstract] [Full Text] [Related]

  • 15. Activation of extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells.
    Yu W, Liao QY, Hantash FM, Sanders BG, Kline K.
    Cancer Res; 2001 Sep 01; 61(17):6569-76. PubMed ID: 11522656
    [Abstract] [Full Text] [Related]

  • 16. Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
    Xu GW, Mymryk JS, Cairncross JG.
    Int J Cancer; 2005 Aug 20; 116(2):187-92. PubMed ID: 15800902
    [Abstract] [Full Text] [Related]

  • 17. Biological and chemical studies on aryl hydrocarbon receptor induction by the p53 inhibitor pifithrin-α and its condensation product pifithrin-β.
    Fernández-Cruz ML, Valdehita A, Alonso M, Mann E, Herradón B, Navas JM.
    Life Sci; 2011 Apr 25; 88(17-18):774-83. PubMed ID: 21362431
    [Abstract] [Full Text] [Related]

  • 18. Pifithrin-α enhancing anticancer effect of topotecan on p53-expressing cancer cells.
    Guo J, Tang Q, Wang Q, Sun W, Pu Z, Wang J, Bao Y.
    Eur J Pharm Sci; 2019 Feb 01; 128():61-72. PubMed ID: 30472223
    [Abstract] [Full Text] [Related]

  • 19. [Involvement of p38-p53 signal pathway in resveratrol-induced apoptosis in MCF-7 cells].
    Zhang YH, Guo JG, Guo ZH, Xie SQ.
    Yao Xue Xue Bao; 2011 Nov 01; 46(11):1332-7. PubMed ID: 22260024
    [Abstract] [Full Text] [Related]

  • 20. The role of p53-induced apoptosis in cerebral ischemia: effects of the p53 inhibitor pifithrin alpha.
    Leker RR, Aharonowiz M, Greig NH, Ovadia H.
    Exp Neurol; 2004 Jun 01; 187(2):478-86. PubMed ID: 15144874
    [Abstract] [Full Text] [Related]

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