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Journal Abstract Search

237 related items for PubMed ID: 12885242

  • 21. Recent progress in the CYP51 research focusing on its unique evolutionary and functional characteristics as a diversozyme P450.
    Aoyama Y.
    Front Biosci; 2005 May 01; 10():1546-57. PubMed ID: 15769645
    [Abstract] [Full Text] [Related]

  • 22.
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  • 23. Sterol 14alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms.
    Lepesheva GI, Waterman MR.
    Biochim Biophys Acta; 2007 Mar 01; 1770(3):467-77. PubMed ID: 16963187
    [Abstract] [Full Text] [Related]

  • 24. Many facets of mammalian lanosterol 14alpha-demethylase from the evolutionarily conserved cytochrome P450 family CYP51.
    Debeljak N, Fink M, Rozman D.
    Arch Biochem Biophys; 2003 Jan 01; 409(1):159-71. PubMed ID: 12464255
    [Abstract] [Full Text] [Related]

  • 25. Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives.
    Lewis DF, Wiseman A, Tarbit MH.
    J Enzyme Inhib; 1999 Jan 01; 14(3):175-92. PubMed ID: 10445042
    [Abstract] [Full Text] [Related]

  • 26. [Structural-functional motifs of sterol 14-alpha demethylases (CYP51)].
    Lisitsina AV, Gusev SA, Miroshnichenko IuV, Kuznetsova GP, Lazarev VN, Skvortsov VS, Karuzina II, Govorun VM, Archakov AI.
    Biomed Khim; 2004 Jan 01; 50(6):554-65. PubMed ID: 15707270
    [Abstract] [Full Text] [Related]

  • 27. Cloning and expression in Escherichia coli of the obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals.
    Bak S, Kahn RA, Olsen CE, Halkier BA.
    Plant J; 1997 Feb 01; 11(2):191-201. PubMed ID: 9076987
    [Abstract] [Full Text] [Related]

  • 28. Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions.
    Sheng C, Zhang W, Zhang M, Song Y, Ji H, Zhu J, Yao J, Yu J, Yang S, Zhou Y, Zhu J, Lu J.
    J Biomol Struct Dyn; 2004 Aug 01; 22(1):91-9. PubMed ID: 15214809
    [Abstract] [Full Text] [Related]

  • 29. Structure and mapping of the human lanosterol 14alpha-demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; comparison of exon/intron organization with other mammalian and fungal CYP genes.
    Rozman D, Strömstedt M, Tsui LC, Scherer SW, Waterman MR.
    Genomics; 1996 Dec 15; 38(3):371-81. PubMed ID: 8975714
    [Abstract] [Full Text] [Related]

  • 30. Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): a live example showing the selection of altered P450 through interaction with environmental compounds.
    Kudo M, Ohi M, Aoyama Y, Nitahara Y, Chung SK, Yoshida Y.
    J Biochem; 2005 May 15; 137(5):625-32. PubMed ID: 15944416
    [Abstract] [Full Text] [Related]

  • 31. Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography.
    Podust LM, von Kries JP, Eddine AN, Kim Y, Yermalitskaya LV, Kuehne R, Ouellet H, Warrier T, Alteköster M, Lee JS, Rademann J, Oschkinat H, Kaufmann SH, Waterman MR.
    Antimicrob Agents Chemother; 2007 Nov 15; 51(11):3915-23. PubMed ID: 17846131
    [Abstract] [Full Text] [Related]

  • 32. [Expression of the Mycobacterium tuberculosis cytochrome CYP51 gene in Escherichia coli].
    Shavkunov AS, Lazarev VN, Zgoda VG, Govorun VM, Levi P, Janssen P, Archakov AI.
    Biomed Khim; 2003 Nov 15; 49(2):145-52. PubMed ID: 14565078
    [Abstract] [Full Text] [Related]

  • 33. The R467K amino acid substitution in Candida albicans sterol 14alpha-demethylase causes drug resistance through reduced affinity.
    Lamb DC, Kelly DE, White TC, Kelly SL.
    Antimicrob Agents Chemother; 2000 Jan 15; 44(1):63-7. PubMed ID: 10602724
    [Abstract] [Full Text] [Related]

  • 34. Binding of a physiological substrate causes large-scale conformational reorganization in cytochrome P450 51.
    Hargrove TY, Wawrzak Z, Fisher PM, Child SA, Nes WD, Guengerich FP, Waterman MR, Lepesheva GI.
    J Biol Chem; 2018 Dec 14; 293(50):19344-19353. PubMed ID: 30327430
    [Abstract] [Full Text] [Related]

  • 35. Human sterol 14alpha-demethylase activity is enhanced by the membrane-bound state of cytochrome b(5).
    Lamb DC, Kaderbhai NN, Venkateswarlu K, Kelly DE, Kelly SL, Kaderbhai MA.
    Arch Biochem Biophys; 2001 Nov 01; 395(1):78-84. PubMed ID: 11673868
    [Abstract] [Full Text] [Related]

  • 36. MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51.
    Zanno A, Kwiatkowski N, Vaz AD, Guardiola-Diaz HM.
    Biochim Biophys Acta; 2005 Nov 01; 1707(2-3):157-69. PubMed ID: 15863094
    [Abstract] [Full Text] [Related]

  • 37. Sterol 14-demethylase P450 (CYP51) provides a breakthrough for the discussion on the evolution of cytochrome P450 gene superfamily.
    Yoshida Y, Aoyama Y, Noshiro M, Gotoh O.
    Biochem Biophys Res Commun; 2000 Jul 14; 273(3):799-804. PubMed ID: 10891326
    [Abstract] [Full Text] [Related]

  • 38. Spin equilibrium and O₂-binding kinetics of Mycobacterium tuberculosis CYP51 with mutations in the histidine-threonine dyad.
    Jennings GK, Modi A, Elenewski JE, Ritchie CM, Nguyen T, Ellis KC, Hackett JC.
    J Inorg Biochem; 2014 Jul 14; 136():81-91. PubMed ID: 24793591
    [Abstract] [Full Text] [Related]

  • 39.
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  • 40. The three human cytochrome P450 lanosterol 14 alpha-demethylase (CYP51) genes reside on chromosomes 3, 7, and 13: structure of the two retrotransposed pseudogenes, association with a line-1 element, and evolution of the human CYP51 family.
    Rozman D, Strömstedt M, Waterman MR.
    Arch Biochem Biophys; 1996 Sep 15; 333(2):466-74. PubMed ID: 8809088
    [Abstract] [Full Text] [Related]

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