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203 related items for PubMed ID: 12898520

  • 1. Non-apoptogenic killing of hela cervical carcinoma cells after short exposure to the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
    Wesierska-Gadek J, Gueorguieva M, Schloffer D, Uhl M, Wojciechowski J.
    J Cell Biochem; 2003 Aug 15; 89(6):1222-34. PubMed ID: 12898520
    [Abstract] [Full Text] [Related]

  • 2. Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: implication for cytotoxicity.
    Bai P, Hegedus C, Erdélyi K, Szabó E, Bakondi E, Gergely S, Szabó C, Virág L.
    Toxicol Lett; 2007 May 15; 170(3):203-13. PubMed ID: 17428624
    [Abstract] [Full Text] [Related]

  • 3. Oxidative stress initiates DNA damager MNNG-induced poly(ADP-ribose)polymerase-1-dependent parthanatos cell death.
    Chiu LY, Ho FM, Shiah SG, Chang Y, Lin WW.
    Biochem Pharmacol; 2011 Feb 01; 81(3):459-70. PubMed ID: 21056551
    [Abstract] [Full Text] [Related]

  • 4. Role of poly(ADP-ribose) polymerase in rapid intracellular acidification induced by alkylating DNA damage.
    Affar el B, Shah RG, Dallaire AK, Castonguay V, Shah GM.
    Proc Natl Acad Sci U S A; 2002 Jan 08; 99(1):245-50. PubMed ID: 11756665
    [Abstract] [Full Text] [Related]

  • 5. Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.
    Pogrebniak A, Schemainda I, Pelka-Fleischer R, Nüssler V, Hasmann M.
    Eur J Med Res; 2003 Oct 22; 8(10):438-50. PubMed ID: 14594650
    [Abstract] [Full Text] [Related]

  • 6. The monofunctional alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways.
    Kim WJ, Beardsley DI, Adamson AW, Brown KD.
    Toxicol Appl Pharmacol; 2005 Jan 01; 202(1):84-98. PubMed ID: 15589979
    [Abstract] [Full Text] [Related]

  • 7. Functional interactions of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the M(r) 85,000 proteolytic fragment.
    Kumari SR, Mendoza-Alvarez H, Alvarez-Gonzalez R.
    Cancer Res; 1998 Nov 15; 58(22):5075-8. PubMed ID: 9823314
    [Abstract] [Full Text] [Related]

  • 8. N-methyl-N'-nitro-N-nitrosoguanidine activates multiple cell death mechanisms in human fibroblasts.
    Lee MW, Kim WJ, Beardsley DI, Brown KD.
    DNA Cell Biol; 2007 Sep 15; 26(9):683-94. PubMed ID: 17678437
    [Abstract] [Full Text] [Related]

  • 9. Signaling of DNA damage is not sufficient to induce p53 response: (re)activation of wt p53 protein strongly depends on cellular context.
    Wesierska-Gadek J, Gueorguieva M, Komina O, Schmid G, Kramer MP.
    J Cell Biochem; 2008 Apr 01; 103(5):1607-20. PubMed ID: 17879942
    [Abstract] [Full Text] [Related]

  • 10. Molecular and cellular influences of butylated hydroxyanisole on Chinese hamster V79 cells treated with N-methyl-N'-nitro-N-nitrosoguanidine: antimutagenicity of butylated hydroxyanisole.
    Slamenová D, Horváthová E, Robichová S, Hrusovská L, Gábelová A, Kleibl K, Jakubíková J, Sedlák J.
    Environ Mol Mutagen; 2003 Apr 01; 41(1):28-36. PubMed ID: 12552589
    [Abstract] [Full Text] [Related]

  • 11. Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.
    Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J, Susin SA.
    Mol Cell Biol; 2007 Jul 01; 27(13):4844-62. PubMed ID: 17470554
    [Abstract] [Full Text] [Related]

  • 12. MNNG induces dramatic DNA damage and non-apoptotic changes in cervical carcinoma HeLa cells.
    Wsierska-Gadek J, Gueorguieva M, Wojciechowski J.
    Ann N Y Acad Sci; 2003 Dec 01; 1010():278-82. PubMed ID: 15033734
    [Abstract] [Full Text] [Related]

  • 13. Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damage.
    Liu X, Luo X, Shi Y, Zhu GD, Penning T, Giranda VL, Luo Y.
    Cancer Biol Ther; 2008 Jun 01; 7(6):934-41. PubMed ID: 18376143
    [Abstract] [Full Text] [Related]

  • 14. Human melanoma cells selected for resistance to apoptosis by prolonged exposure to tumor necrosis factor-related apoptosis-inducing ligand are more vulnerable to necrotic cell death induced by cisplatin.
    Zhang XD, Wu JJ, Gillespie S, Borrow J, Hersey P.
    Clin Cancer Res; 2006 Feb 15; 12(4):1355-64. PubMed ID: 16489094
    [Abstract] [Full Text] [Related]

  • 15. Induction of apoptosis and G2/M arrest by N-methyl-N'-nitro-N-nitrosoguanidine in human prostate carcinoma cells.
    Park C, Choi BT, Cheong J, Moon SK, Kim CH, Lee WH, Choi YH.
    Mutat Res; 2004 Oct 10; 563(2):139-49. PubMed ID: 15364280
    [Abstract] [Full Text] [Related]

  • 16. Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.
    Pogrebniak A, Schemainda I, Azzam K, Pelka-Fleischer R, Nüssler V, Hasmann M.
    Eur J Med Res; 2006 Aug 30; 11(8):313-21. PubMed ID: 17052966
    [Abstract] [Full Text] [Related]

  • 17. DNA damage and cytotoxicity of 2-chloroethyl (methylsulfonyl)methanesulfonate (NSC 338947) produced in human colon carcinoma cells with or without methylating agent pretreatment.
    Hartley JA, Gibson NW.
    Cancer Res; 1986 Aug 30; 46(8):3871-5. PubMed ID: 3015378
    [Abstract] [Full Text] [Related]

  • 18. Synergistic cytotoxicity of N-methyl-N'-nitro-N-nitrosoguanidine and absence of poly(ADP-ribose) glycohydrolase involves chromatin decondensation.
    Zhou Y, Feng X, Koh DW.
    Int J Oncol; 2011 Jul 30; 39(1):121-7. PubMed ID: 21519789
    [Abstract] [Full Text] [Related]

  • 19. Multicell spheroid response to drugs predicted with the comet assay.
    Olive PL, Banáth JP.
    Cancer Res; 1997 Dec 15; 57(24):5528-33. PubMed ID: 9407963
    [Abstract] [Full Text] [Related]

  • 20. Apaf-1 deficient mouse fibroblasts are resistant to MNNG and MMS-induced apoptotic death without attenuation of Bcl-2 decline.
    Tomicic MT, Christmann M, Fabian K, Kaina B.
    Toxicol Appl Pharmacol; 2005 Sep 01; 207(2 Suppl):117-22. PubMed ID: 16019050
    [Abstract] [Full Text] [Related]

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