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125 related items for PubMed ID: 12898644

  • 1. Influence of culture time on the expression of drug-metabolizing enzymes in primary human hepatocytes and hepatoma cell line HepG2.
    Wilkening S, Bader A.
    J Biochem Mol Toxicol; 2003; 17(4):207-13. PubMed ID: 12898644
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  • 2. Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties.
    Wilkening S, Stahl F, Bader A.
    Drug Metab Dispos; 2003 Aug; 31(8):1035-42. PubMed ID: 12867492
    [Abstract] [Full Text] [Related]

  • 3. Comparative analysis of phase I and II enzyme activities in 5 hepatic cell lines identifies Huh-7 and HCC-T cells with the highest potential to study drug metabolism.
    Lin J, Schyschka L, Mühl-Benninghaus R, Neumann J, Hao L, Nussler N, Dooley S, Liu L, Stöckle U, Nussler AK, Ehnert S.
    Arch Toxicol; 2012 Jan; 86(1):87-95. PubMed ID: 21735230
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  • 4. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
    Westerink WM, Schoonen WG.
    Toxicol In Vitro; 2007 Dec; 21(8):1581-91. PubMed ID: 17637504
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  • 5. Phase II enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
    Westerink WM, Schoonen WG.
    Toxicol In Vitro; 2007 Dec; 21(8):1592-602. PubMed ID: 17716855
    [Abstract] [Full Text] [Related]

  • 6. Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells.
    Harris AJ, Dial SL, Casciano DA.
    Mutat Res; 2004 May 18; 549(1-2):79-99. PubMed ID: 15120964
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  • 7. Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes.
    Mathijs K, Kienhuis AS, Brauers KJ, Jennen DG, Lahoz A, Kleinjans JC, van Delft JH.
    Drug Metab Dispos; 2009 Jun 18; 37(6):1305-11. PubMed ID: 19251822
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  • 8. Effects of cell culture conditions on primary rat hepatocytes-cell morphology and differential gene expression.
    Tuschl G, Mueller SO.
    Toxicology; 2006 Feb 01; 218(2-3):205-15. PubMed ID: 16337326
    [Abstract] [Full Text] [Related]

  • 9. The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.
    Guillouzo A, Corlu A, Aninat C, Glaise D, Morel F, Guguen-Guillouzo C.
    Chem Biol Interact; 2007 May 20; 168(1):66-73. PubMed ID: 17241619
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  • 10. Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.
    Aninat C, Piton A, Glaise D, Le Charpentier T, Langouët S, Morel F, Guguen-Guillouzo C, Guillouzo A.
    Drug Metab Dispos; 2006 Jan 20; 34(1):75-83. PubMed ID: 16204462
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  • 12. Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction.
    Hariparsad N, Carr BA, Evers R, Chu X.
    Drug Metab Dispos; 2008 Jun 20; 36(6):1046-55. PubMed ID: 18332078
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  • 14. Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line.
    Le Vee M, Jigorel E, Glaise D, Gripon P, Guguen-Guillouzo C, Fardel O.
    Eur J Pharm Sci; 2006 May 20; 28(1-2):109-17. PubMed ID: 16488578
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  • 18. Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.
    Gómez-Lechón MJ, Castell JV, Donato MT.
    Chem Biol Interact; 2007 May 20; 168(1):30-50. PubMed ID: 17134688
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  • 19. Well maintained expression of CYP genes in sandwich-culturing hepatocytes: quantitative analysis using real-time PCR method.
    Toritsuka N, Nonogaki Y, Hori Y, Sawada S, Shoun H, Motooka S.
    Res Commun Mol Pathol Pharmacol; 2001 May 20; 110(5-6):311-8. PubMed ID: 12889523
    [Abstract] [Full Text] [Related]

  • 20. Blood monocyte-derived neohepatocytes as in vitro test system for drug metabolism.
    Ehnert S, Nussler AK, Lehmann A, Dooley S.
    Drug Metab Dispos; 2008 Sep 20; 36(9):1922-9. PubMed ID: 18559486
    [Abstract] [Full Text] [Related]

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