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Journal Abstract Search

202 related items for PubMed ID: 12899530

  • 1. Design, synthesis, and biological studies of the A-ring-modified 1,25-dihydroxyvitamin D3 analogs.
    Takayama H, Kittaka A, Fujishima T, Suhara Y.
    Recent Results Cancer Res; 2003; 164():289-317. PubMed ID: 12899530
    [Abstract] [Full Text] [Related]

  • 2. Systematic studies on synthesis, structural elucidation, and biological evaluation of A-ring diastereomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 20-epi-2-methyl-1alpha,25-dihydroxyvitamin D(3).
    Takayama H, Konno K, Fujishima T, Maki S, Liu Z, Miura D, Chokki M, Ishizuka S, Smith C, DeLuca HF, Nakagawa K, Kurobe M, Okano T.
    Steroids; 2001; 66(3-5):277-85. PubMed ID: 11179735
    [Abstract] [Full Text] [Related]

  • 3. Highly potent cell differentiation-inducing analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and biological activity of 2-methyl-1,25-dihydroxyvitamin D3 with side-chain modifications.
    Fujishima T, Zhaopeng L, Konno K, Nakagawa K, Okano T, Yamaguchi K, Takayama H.
    Bioorg Med Chem; 2001 Feb; 9(2):525-35. PubMed ID: 11249144
    [Abstract] [Full Text] [Related]

  • 4. Novel ring A stereoisomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 2-methyl-20-epi-1alpha,25-dihydroxyvitamin D(3): transactivation of target genes and modulation of differentiation in human promyelocytic leukemia (HL-60) cells.
    Nakagawa K, Kurobe M, Ozono K, Konno K, Fujishima T, Takayama H, Okano T.
    Biochem Pharmacol; 2000 Mar 15; 59(6):691-702. PubMed ID: 10677586
    [Abstract] [Full Text] [Related]

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  • 6. Novel 2-alkyl-1alpha,25-dihydroxy-19-norvitamin D3: efficient synthesis with Julia olefination, evaluation of biological activity and development of new analyzing system for co-activator recruitment.
    Arai MA, Kittaka A.
    Anticancer Res; 2006 Mar 15; 26(4A):2621-31. PubMed ID: 16886672
    [Abstract] [Full Text] [Related]

  • 7. [Structural refinement of seco-steroidal skeleton and the biological activity through nuclear receptors].
    Kittaka A.
    Yakugaku Zasshi; 2008 Sep 15; 128(9):1235-50. PubMed ID: 18758137
    [Abstract] [Full Text] [Related]

  • 8. Syntheses and biological evaluation of novel 2alpha-substituted 1alpha,25-dihydroxyvitamin D3 analogues.
    Suhara Y, Nihei KI, Tanigawa H, Fujishima T, Konno K, Nakagawa K, Okano T, Takayama H.
    Bioorg Med Chem Lett; 2000 May 15; 10(10):1129-32. PubMed ID: 10843234
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  • 10. Analogs of 1alpha,25-dihydroxyvitamin D3 with high potency in induction of osteoclastogenesis and prevention of dendritic cell differentiation: synthesis and biological evaluation of 2-substituted 19-norvitamin D analogs.
    Shimazaki M, Miyamoto Y, Yamamoto K, Yamada S, Takami M, Shinki T, Udagawa N, Shimizu M.
    Bioorg Med Chem; 2006 Jul 01; 14(13):4645-56. PubMed ID: 16513359
    [Abstract] [Full Text] [Related]

  • 11. The antagonism between 2-methyl-1,25-dihydroxyvitamin D3 and 2-methyl-20-epi-1,25-dihydroxyvitamin D3 in non-genomic pathway-mediated biological responses induced by 1alpha,25-dihydroxyvitamin D3 assessed by NB4 cell differentiation.
    Miura D, Norman AW, Mizwicki MT, Fujishima T, Konno K, Kittaka A, Takayama H, Ishizuka S.
    J Steroid Biochem Mol Biol; 2005 Apr 01; 94(5):469-79. PubMed ID: 15876412
    [Abstract] [Full Text] [Related]

  • 12. Concise synthesis and biological activities of 2alpha-alkyl- and 2alpha-(omega-hydroxyalkyl)-20-epi-1alpha,25-dihydroxyvitamin D3.
    Honzawa S, Suhara Y, Nihei K, Saito N, Kishimoto S, Fujishima T, Kurihara M, Sugiura T, Waku K, Takayama H, Kittaka A.
    Bioorg Med Chem Lett; 2003 Oct 20; 13(20):3503-6. PubMed ID: 14505658
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological activity of 22-iodo- and (E)-20(22)-dehydro analogues of 1alpha,25-dihydroxyvitamin D3.
    Sicinski RR, DeLuca HF.
    Bioorg Med Chem; 1999 Dec 20; 7(12):2877-89. PubMed ID: 10658592
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of 1alpha,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1 alpha,25-dihydroxyvitamin D3 antagonist.
    Kato Y, Nakano Y, Sano H, Tanatani A, Kobayashi H, Shimazawa R, Koshino H, Hashimoto Y, Nagasawa K.
    Bioorg Med Chem Lett; 2004 May 17; 14(10):2579-83. PubMed ID: 15109656
    [Abstract] [Full Text] [Related]

  • 15. Rational design, synthesis, and biological activity of novel conformationally restricted vitamin D analogues, (22R)- and (22S)-22-ethyl-1,25-dihydroxy-23,24-didehydro-24a,24b-dihomo-20-epivitamin D(3).
    Masuno H, Yamamoto K, Wang X, Choi M, Ooizumi H, Shinki T, Yamada S.
    J Med Chem; 2002 Apr 25; 45(9):1825-34. PubMed ID: 11960494
    [Abstract] [Full Text] [Related]

  • 16. 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure.
    Shimizu M, Miyamoto Y, Takaku H, Matsuo M, Nakabayashi M, Masuno H, Udagawa N, DeLuca HF, Ikura T, Ito N.
    Bioorg Med Chem; 2008 Jul 15; 16(14):6949-64. PubMed ID: 18539034
    [Abstract] [Full Text] [Related]

  • 17. A novel and practical route to A-ring enyne synthon for 1 alpha,25-dihydroxyvitamin D3 analogs: synthesis of A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D2 and 3-methyl-1,25-dihydroxyvitamin D3.
    Konno K, Maki S, Fujishima T, Liu Z, Miura D, Chokki M, Takayama H.
    Bioorg Med Chem Lett; 1998 Jan 20; 8(2):151-6. PubMed ID: 9871644
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological evaluation of 1α,25-dihydroxyvitamin D3 analogues with aromatic side chains attached at C-17.
    Liu C, Zhao GD, Mao X, Suenaga T, Fujishima T, Zhang CM, Liu ZP.
    Eur J Med Chem; 2014 Oct 06; 85():569-75. PubMed ID: 25127149
    [Abstract] [Full Text] [Related]

  • 19. Effect of 25-hydroxyl group orientation on biological activity and binding to the 1alpha,25-dihydroxy vitamin D3 receptor.
    Collins ED, Bishop JE, Bula CM, Acevedo A, Okamura WH, Norman AW.
    J Steroid Biochem Mol Biol; 2005 Mar 06; 94(4):279-88. PubMed ID: 15857747
    [Abstract] [Full Text] [Related]

  • 20. Recent results on A-ring modification of 1alpha,25-dihydroxyvitamin D3: design and synthesis of VDR-agonists and antagonists with high biological activity.
    Saito N, Honzawa S, Kittaka A.
    Curr Top Med Chem; 2006 Mar 06; 6(12):1273-88. PubMed ID: 16848741
    [Abstract] [Full Text] [Related]

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