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197 related items for PubMed ID: 12902979

  • 1. Loss of inhibitor of apoptosis proteins as a determinant of polyamine analog-induced apoptosis in human melanoma cells.
    Chen Y, Kramer DL, Li F, Porter CW.
    Oncogene; 2003 Aug 07; 22(32):4964-72. PubMed ID: 12902979
    [Abstract] [Full Text] [Related]

  • 2. Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells.
    Chen Y, Kramer DL, Diegelman P, Vujcic S, Porter CW.
    Cancer Res; 2001 Sep 01; 61(17):6437-44. PubMed ID: 11522638
    [Abstract] [Full Text] [Related]

  • 3. Small interfering RNA suppression of polyamine analog-induced spermidine/spermine n1-acetyltransferase.
    Chen Y, Kramer DL, Jell J, Vujcic S, Porter CW.
    Mol Pharmacol; 2003 Nov 01; 64(5):1153-9. PubMed ID: 14573765
    [Abstract] [Full Text] [Related]

  • 4. The polyamine analogue N1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines.
    Stanic' I, Facchini A, Borzì RM, Stefanelli C, Flamigni F.
    J Cell Physiol; 2009 Apr 01; 219(1):109-16. PubMed ID: 19097065
    [Abstract] [Full Text] [Related]

  • 5. Activation of polyamine catabolism by N1,N11-diethylnorspermine leads to cell death in glioblastoma.
    Jiang R, Choi W, Khan A, Hess K, Gerner EW, Casero RA, Yung WK, Hamilton SR, Zhang W.
    Int J Oncol; 2007 Aug 01; 31(2):431-40. PubMed ID: 17611701
    [Abstract] [Full Text] [Related]

  • 6. Correlations between polyamine analogue-induced increases in spermidine/spermine N1-acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines.
    Porter CW, Ganis B, Libby PR, Bergeron RJ.
    Cancer Res; 1991 Jul 15; 51(14):3715-20. PubMed ID: 2065327
    [Abstract] [Full Text] [Related]

  • 7. The role of mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells.
    Chen Y, Alm K, Vujcic S, Kramer DL, Kee K, Diegelman P, Porter CW.
    Cancer Res; 2003 Jul 01; 63(13):3619-25. PubMed ID: 12839950
    [Abstract] [Full Text] [Related]

  • 8. Effects of polyamines, polyamine analogs, and inhibitors of protein synthesis on spermidine-spermine N1-acetyltransferase gene expression.
    Fogel-Petrovic M, Vujcic S, Brown PJ, Haddox MK, Porter CW.
    Biochemistry; 1996 Nov 12; 35(45):14436-44. PubMed ID: 8916930
    [Abstract] [Full Text] [Related]

  • 9. Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion.
    Bernacki RJ, Oberman EJ, Seweryniak KE, Atwood A, Bergeron RJ, Porter CW.
    Clin Cancer Res; 1995 Aug 12; 1(8):847-57. PubMed ID: 9816054
    [Abstract] [Full Text] [Related]

  • 10. Differential effects of the spermine analog, N1, N12-bis(ethyl)-spermine, on polyamine metabolism and cell growth in human melanoma cell lines and melanocytes.
    Shappell NW, Miller JT, Bergeron RJ, Porter CW.
    Anticancer Res; 1992 Aug 12; 12(4):1083-9. PubMed ID: 1503400
    [Abstract] [Full Text] [Related]

  • 11. Novel anti-apoptotic effect of Bcl-2: prevention of polyamine depletion-induced cell death.
    Holst CM, Johansson VM, Alm K, Oredsson SM.
    Cell Biol Int; 2008 Jan 12; 32(1):66-74. PubMed ID: 17920946
    [Abstract] [Full Text] [Related]

  • 12. Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N1-acetyltransferase show enhanced sensitivity to the polyamine analog, N1, N11-diethylnorspermine.
    Alhonen L, Pietilä M, Halmekytö M, Kramer DL, Jänne J, Porter CW.
    Mol Pharmacol; 1999 Apr 12; 55(4):693-8. PubMed ID: 10101027
    [Abstract] [Full Text] [Related]

  • 13. Collateral sensitivity of human melanoma multidrug-resistant variants to the polyamine analogue, N1,N11-diethylnorspermine.
    Porter CW, Ganis B, Rustum Y, Wrzosek C, Kramer DL, Bergeron RJ.
    Cancer Res; 1994 Nov 15; 54(22):5917-24. PubMed ID: 7954423
    [Abstract] [Full Text] [Related]

  • 14. Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytes.
    Stanic I, Cetrullo S, Facchini A, Stefanelli C, Borzì RM, Tantini B, Guarnieri C, Caldarera CM, Flamigni F.
    J Cell Physiol; 2008 Jul 15; 216(1):153-61. PubMed ID: 18231987
    [Abstract] [Full Text] [Related]

  • 15. Polyamine analogue induction of the p53-p21WAF1/CIP1-Rb pathway and G1 arrest in human melanoma cells.
    Kramer DL, Vujcic S, Diegelman P, Alderfer J, Miller JT, Black JD, Bergeron RJ, Porter CW.
    Cancer Res; 1999 Mar 15; 59(6):1278-86. PubMed ID: 10096560
    [Abstract] [Full Text] [Related]

  • 16. Apoptosis induced by the potential chemotherapeutic drug N1, N11-Diethylnorspermine in a neuroblastoma cell line.
    Söderstjerna E, Holst CM, Alm K, Oredsson SM.
    Anticancer Drugs; 2010 Nov 15; 21(10):917-26. PubMed ID: 20729713
    [Abstract] [Full Text] [Related]

  • 17. Sequence specific antisense oligonucleotide analog interference with spermidine/spermine N1-acetyltransferase gene expression.
    Fogel-Petrovic M, Vujcic S, Häner R, Regenass U, Mett H, Porter CW.
    Anticancer Res; 1996 Nov 15; 16(5A):2517-23. PubMed ID: 8917345
    [Abstract] [Full Text] [Related]

  • 18. Antitumor activity of N1,N11-bis(ethyl)norspermine against human melanoma xenografts and possible biochemical correlates of drug action.
    Porter CW, Bernacki RJ, Miller J, Bergeron RJ.
    Cancer Res; 1993 Feb 01; 53(3):581-6. PubMed ID: 8425191
    [Abstract] [Full Text] [Related]

  • 19. Molecular mechanisms underlying N1, N11-diethylnorspermine-induced apoptosis in a human breast cancer cell line.
    Holst CM, Staaf J, Jönsson G, Hegardt C, Oredsson SM.
    Anticancer Drugs; 2008 Oct 01; 19(9):871-83. PubMed ID: 18766001
    [Abstract] [Full Text] [Related]

  • 20. Induction of spermidine/spermine N1-acetyltransferase in breast cancer tissues treated with the polyamine analogue N1, N11-diethylnorspermine.
    Gabrielson E, Tully E, Hacker A, Pegg AE, Davidson NE, Casero RA.
    Cancer Chemother Pharmacol; 2004 Aug 01; 54(2):122-6. PubMed ID: 15138709
    [Abstract] [Full Text] [Related]

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