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Journal Abstract Search
183 related items for PubMed ID: 12904300
1. Catalysis by RNase P RNA: unique features and unprecedented active site plasticity. Persson T, Cuzic S, Hartmann RK. J Biol Chem; 2003 Oct 31; 278(44):43394-401. PubMed ID: 12904300 [Abstract] [Full Text] [Related]
3. Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkage. Warnecke JM, Sontheimer EJ, Piccirilli JA, Hartmann RK. Nucleic Acids Res; 2000 Feb 01; 28(3):720-7. PubMed ID: 10637323 [Abstract] [Full Text] [Related]
4. Effects of phosphorothioate modifications on precursor tRNA processing by eukaryotic RNase P enzymes. Pfeiffer T, Tekos A, Warnecke JM, Drainas D, Engelke DR, Séraphin B, Hartmann RK. J Mol Biol; 2000 May 12; 298(4):559-65. PubMed ID: 10788319 [Abstract] [Full Text] [Related]
6. Helix P4 is a divalent metal ion binding site in the conserved core of the ribonuclease P ribozyme. Christian EL, Kaye NM, Harris ME. RNA; 2000 Apr 12; 6(4):511-9. PubMed ID: 10786842 [Abstract] [Full Text] [Related]
8. Ribonuclease P (RNase P) RNA is converted to a Cd(2+)-ribozyme by a single Rp-phosphorothioate modification in the precursor tRNA at the RNase P cleavage site. Warnecke JM, Fürste JP, Hardt WD, Erdmann VA, Hartmann RK. Proc Natl Acad Sci U S A; 1996 Aug 20; 93(17):8924-8. PubMed ID: 8799129 [Abstract] [Full Text] [Related]
12. The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction. Herschlag D, Eckstein F, Cech TR. Biochemistry; 1993 Aug 17; 32(32):8312-21. PubMed ID: 7688573 [Abstract] [Full Text] [Related]
13. Escherichia coli RNase P RNA: substrate ribose modifications at G+1, but not nucleotide -1/+73 base pairing, affect the transition state for cleavage chemistry. Cuzic S, Heidemann KA, Wöhnert J, Hartmann RK. J Mol Biol; 2008 May 23; 379(1):1-8. PubMed ID: 18452950 [Abstract] [Full Text] [Related]
18. Probing the role of metal ions in RNA catalysis: kinetic and thermodynamic characterization of a metal ion interaction with the 2'-moiety of the guanosine nucleophile in the Tetrahymena group I ribozyme. Shan SO, Herschlag D. Biochemistry; 1999 Aug 24; 38(34):10958-75. PubMed ID: 10460151 [Abstract] [Full Text] [Related]