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104 related items for PubMed ID: 12906758
1. Stereospecific reduction of the original anticancer drug oracin in rat extrahepatic tissues. Szotáková B, Skálová L, Jílek P, Buchta V, Wsól V. J Pharm Pharmacol; 2003 Jul; 55(7):1003-11. PubMed ID: 12906758 [Abstract] [Full Text] [Related]
2. Sex differences in stereospecificity of oracin reductases in rat in vitro and in vivo. Wsól V, Skálová L, Szotáková B, Trejtnar F, Kvasnicková E. Chirality; 1999 Jul; 11(5-6):505-9. PubMed ID: 10368924 [Abstract] [Full Text] [Related]
3. A comparison between stereospecificity of oracin reduction and stereoselectivity of oxidation of 11-dihydrooracin enantiomers in vitro in rat and guinea pig. Skálová L, Wsól V, Szotáková B, Kvasnicková E. Chirality; 1999 Jul; 11(5-6):510-5. PubMed ID: 10368925 [Abstract] [Full Text] [Related]
4. Partial purification and characterization of a new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin. Skarydová L, Skarka A, Novotná R, Zivná L, Martin HJ, Wsól V, Maser E. Toxicology; 2009 Oct 01; 264(1-2):52-60. PubMed ID: 19635524 [Abstract] [Full Text] [Related]
5. The novel anticancer drug oracin: different stereospecificity and cooperativity for carbonyl reduction by purified human liver 11beta-hydroxysteroid dehydrogenase type 1. Wsól V, Szotáková B, Skálová L, Maser E. Toxicology; 2004 May 03; 197(3):253-61. PubMed ID: 15033547 [Abstract] [Full Text] [Related]
10. Stereochemical aspects of carbonyl reduction of the original anticancer drug oracin by mouse liver microsomes and purified 11beta-hydroxysteroid dehydrogenase type 1. Wsól V, Szotáková B, Skálová L, Maser E. Chem Biol Interact; 2003 Feb 01; 143-144():459-68. PubMed ID: 12604232 [Abstract] [Full Text] [Related]
11. Central composite design as a powerful optimisation technique for enantioresolution of the rac-11-dihydrooracin--the principal metabolite of the potential cytostatic drug oracin. Wsól V, Fell AF. J Biochem Biophys Methods; 2002 Dec 31; 54(1-3):377-90. PubMed ID: 12543513 [Abstract] [Full Text] [Related]
13. Stereospecificity of flobufen metabolism in guinea pigs in vitro and in vivo: phase I of biotransformation. Kral R, Skalova L, Szotakova B, Babu YN, Wsol V. Chirality; 2004 Jan 31; 16(1):1-9. PubMed ID: 14628293 [Abstract] [Full Text] [Related]
14. High-performance liquid chromatographic assay for the separation and characterization of metabolites of the potential cytostatic drug oracine. Wsól V, Kvasnicková E, Szotáková B, Hais IM. J Chromatogr B Biomed Appl; 1996 May 31; 681(1):169-75. PubMed ID: 8798926 [Abstract] [Full Text] [Related]
15. Activity, stereospecificity, and stereoselectivity of microsomal enzymes in dependence on storage and freezing of rat liver samples. Skálová L, Szotáková B, Wsól V, Král R, Baliharová V, Lamka J. Chirality; 2000 Oct 31; 12(9):649-53. PubMed ID: 10984737 [Abstract] [Full Text] [Related]
16. Stereospecificity and stereoselectivity of flobufen metabolic profile in male rats in vitro and in vivo: phase I of biotransformation. Wsól V, Král R, Skálová L, Szotáková B, Trejtnar F, Flieger M. Chirality; 2001 Oct 31; 13(10):754-9. PubMed ID: 11746815 [Abstract] [Full Text] [Related]
18. Distribution of nitroreductive activity toward nilutamide in rat. Ask K, Décologne N, Asare N, Holme JA, Artur Y, Pelczar H, Camus P. Toxicol Appl Pharmacol; 2004 Nov 15; 201(1):1-9. PubMed ID: 15519603 [Abstract] [Full Text] [Related]
19. Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine. Ireson CR, Jones DJ, Orr S, Coughtrie MW, Boocock DJ, Williams ML, Farmer PB, Steward WP, Gescher AJ. Cancer Epidemiol Biomarkers Prev; 2002 Jan 15; 11(1):105-11. PubMed ID: 11815407 [Abstract] [Full Text] [Related]
20. Inactivation of the anticancer drugs doxorubicin and oracin by aldo-keto reductase (AKR) 1C3. Novotna R, Wsol V, Xiong G, Maser E. Toxicol Lett; 2008 Sep 15; 181(1):1-6. PubMed ID: 18616992 [Abstract] [Full Text] [Related] Page: [Next] [New Search]