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148 related items for PubMed ID: 12906935
1. Probing the active site of aromatase with 2-methyl-substituted androstenedione analogs. Numazawa M, Watari Y, Yamada K, Umemura N, Handa W. Steroids; 2003 Aug; 68(6):503-13. PubMed ID: 12906935 [Abstract] [Full Text] [Related]
4. Enzymic aromatization of 6-alkyl-substituted androgens, potent competitive and mechanism-based inhibitors of aromatase. Numazawa M, Yoshimura A, Oshibe M. Biochem J; 1998 Jan 01; 329 ( Pt 1)(Pt 1):151-6. PubMed ID: 9405288 [Abstract] [Full Text] [Related]
5. Biological aromatization of delta4,6- and delta1,4,6-androgens and their 6-alkyl analogs, potent inhibitors of aromatase. Numazawa M, Yoshimura A. J Steroid Biochem Mol Biol; 1999 Jan 01; 70(4-6):189-96. PubMed ID: 10622407 [Abstract] [Full Text] [Related]
7. Time-dependent aromatase inactivation by 4 beta,5 beta-epoxides of the natural substrate androstenedione and its 19-oxygenated analogs. Numazawa M, Yoshimura A, Tachibana M, Shelangouski M, Ishikawa M. Steroids; 2002 Mar 01; 67(3-4):185-93. PubMed ID: 11856542 [Abstract] [Full Text] [Related]
8. 19-oxygenated derivatives of androst-4-ene-6,17-dione and androst-5-ene-4,17-dione as catalytic probes for the active site of aromatase. Numazawa M, Yamada K, Kidokoro K. Biol Pharm Bull; 1999 Oct 01; 22(10):1134-6. PubMed ID: 10549872 [Abstract] [Full Text] [Related]
11. Gas chromatography-mass spectrometric study of 19-oxygenation of the aromatase inhibitor 19-methylandrostenedione with human placental microsomes. Numazawa M, Nagaoka M, Handa W, Yamada A. Biol Pharm Bull; 2006 Jun 01; 29(6):1242-5. PubMed ID: 16755025 [Abstract] [Full Text] [Related]
12. Probing the binding pocket of the active site of aromatase with 2-phenylaliphatic androsta-1,4-diene-3,17-dione steroids. Takahashi M, Yamashita K, Numazawa M. Steroids; 2010 Apr 01; 75(4-5):330-7. PubMed ID: 20096721 [Abstract] [Full Text] [Related]
13. [Development of aromatase inhibitors and analysis of their inhibitory activities]. Numazawa M. Yakugaku Zasshi; 1998 Dec 01; 118(12):539-53. PubMed ID: 9921263 [Abstract] [Full Text] [Related]
14. Studies on the catalytic function of aromatase: aromatization of 6-alkoxy-substituted androgens. Numazawa M, Ando M, Zennyoji R. J Steroid Biochem Mol Biol; 2002 Sep 01; 82(1):65-73. PubMed ID: 12429140 [Abstract] [Full Text] [Related]
16. 3-Methylene-substituted androgens as novel aromatization inhibitors. Evidence of a requirement for C-3 oxygen in C-19 hydroxylations. Miyairi S, Fishman J. J Biol Chem; 1986 May 25; 261(15):6772-7. PubMed ID: 3700413 [Abstract] [Full Text] [Related]
18. Aromatase reaction of 3-deoxyandrogens: steric mode of the C-19 oxygenation and cleavage of the C10-C19 bond by human placental aromatase. Numazawa M, Nagaoka M, Sohtome N. Biochemistry; 2005 Aug 16; 44(32):10839-45. PubMed ID: 16086586 [Abstract] [Full Text] [Related]
19. Biological characterization of A-ring steroids. Johnston JO, Wright CL, Burkhart JP, Peet NP. J Steroid Biochem Mol Biol; 1993 Mar 16; 44(4-6):623-31. PubMed ID: 8476773 [Abstract] [Full Text] [Related]
20. 6-Alkylandrosta-4,6-diene-3,17-diones and their 1,4,6-triene analogs as aromatase inhibitors. Structure-activity relationships. Numazawa M, Oshibe M, Yamaguchi S. Steroids; 1997 Mar 16; 62(8-9):595-602. PubMed ID: 9292934 [Abstract] [Full Text] [Related] Page: [Next] [New Search]