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Journal Abstract Search

139 related items for PubMed ID: 12915442

  • 1. LEKTI proteolytic processing in human primary keratinocytes, tissue distribution and defective expression in Netherton syndrome.
    Bitoun E, Micheloni A, Lamant L, Bonnart C, Tartaglia-Polcini A, Cobbold C, Al Saati T, Mariotti F, Mazereeuw-Hautier J, Boralevi F, Hohl D, Harper J, Bodemer C, D'Alessio M, Hovnanian A.
    Hum Mol Genet; 2003 Oct 01; 12(19):2417-30. PubMed ID: 12915442
    [Abstract] [Full Text] [Related]

  • 2. LEKTI demonstrable by immunohistochemistry of the skin: a potential diagnostic skin test for Netherton syndrome.
    Ong C, O'Toole EA, Ghali L, Malone M, Smith VV, Callard R, Harper JI.
    Br J Dermatol; 2004 Dec 01; 151(6):1253-7. PubMed ID: 15606522
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  • 4. Netherton syndrome in two Japanese siblings with a novel mutation in the SPINK5 gene: immunohistochemical studies of LEKTI and other epidermal molecules.
    Shimomura Y, Sato N, Kariya N, Takatsuka S, Ito M.
    Br J Dermatol; 2005 Nov 01; 153(5):1026-30. PubMed ID: 16225619
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  • 6. Consequences of C-terminal domains and N-terminal signal peptide deletions on LEKTI secretion, stability, and subcellular distribution.
    Jayakumar A, Kang Y, Henderson Y, Mitsudo K, Liu X, Briggs K, Wang M, Frederick MJ, El-Naggar AK, Bebök Z, Clayman GL.
    Arch Biochem Biophys; 2005 Mar 01; 435(1):89-102. PubMed ID: 15680911
    [Abstract] [Full Text] [Related]

  • 7. SPINK5 and Netherton syndrome: novel mutations, demonstration of missing LEKTI, and differential expression of transglutaminases.
    Raghunath M, Tontsidou L, Oji V, Aufenvenne K, Schürmeyer-Horst F, Jayakumar A, Ständer H, Smolle J, Clayman GL, Traupe H.
    J Invest Dermatol; 2004 Sep 01; 123(3):474-83. PubMed ID: 15304086
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  • 8. rAAV2-mediated restoration of LEKTI in LEKTI-deficient cells from Netherton patients.
    Roedl D, Oji V, Buters JT, Behrendt H, Braun-Falco M.
    J Dermatol Sci; 2011 Mar 01; 61(3):194-8. PubMed ID: 21251800
    [Abstract] [Full Text] [Related]

  • 9. Netherton syndrome: report of two Taiwanese siblings with staphylococcal scalded skin syndrome and mutation of SPINK5.
    Chao SC, Richard G, Lee JY.
    Br J Dermatol; 2005 Jan 01; 152(1):159-65. PubMed ID: 15656819
    [Abstract] [Full Text] [Related]

  • 10. Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis.
    Fortugno P, Bresciani A, Paolini C, Pazzagli C, El Hachem M, D'Alessio M, Zambruno G.
    J Invest Dermatol; 2011 Nov 01; 131(11):2223-32. PubMed ID: 21697885
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI).
    Schechter NM, Choi EJ, Wang ZM, Hanakawa Y, Stanley JR, Kang Y, Clayman GL, Jayakumar A.
    Biol Chem; 2005 Nov 01; 386(11):1173-84. PubMed ID: 16307483
    [Abstract] [Full Text] [Related]

  • 12. SPINK5 gene mutation and decreased LEKTI activity in three Chinese patients with Netherton's syndrome.
    Zhao Y, Ma ZH, Yang Y, Yang SX, Wu LS, Ding BL, Lin ZM, Wang AP, Bu DF, Tu P.
    Clin Exp Dermatol; 2007 Sep 01; 32(5):564-7. PubMed ID: 17608759
    [Abstract] [Full Text] [Related]

  • 13. Correlation between SPINK5 gene mutations and clinical manifestations in Netherton syndrome patients.
    Komatsu N, Saijoh K, Jayakumar A, Clayman GL, Tohyama M, Suga Y, Mizuno Y, Tsukamoto K, Taniuchi K, Takehara K, Diamandis EP.
    J Invest Dermatol; 2008 May 01; 128(5):1148-59. PubMed ID: 17989726
    [Abstract] [Full Text] [Related]

  • 14. A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins.
    Di WL, Hennekam RC, Callard RE, Harper JI.
    Br J Dermatol; 2009 Aug 01; 161(2):404-12. PubMed ID: 19438860
    [Abstract] [Full Text] [Related]

  • 15. The 15-domain serine proteinase inhibitor LEKTI: biochemical properties, genomic organization, and pathophysiological role.
    Mägert HJ, Kreutzmann P, Drögemüller K, Ständker L, Adermann K, Walden M, John H, Korting HC, Forssmann WG.
    Eur J Med Res; 2002 Feb 21; 7(2):49-56. PubMed ID: 11891144
    [Abstract] [Full Text] [Related]

  • 16. LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction.
    Deraison C, Bonnart C, Lopez F, Besson C, Robinson R, Jayakumar A, Wagberg F, Brattsand M, Hachem JP, Leonardsson G, Hovnanian A.
    Mol Biol Cell; 2007 Sep 21; 18(9):3607-19. PubMed ID: 17596512
    [Abstract] [Full Text] [Related]

  • 17. Biochemical features, molecular biology and clinical relevance of the human 15-domain serine proteinase inhibitor LEKTI.
    Walden M, Kreutzmann P, Drögemüller K, John H, Forssmann WG, Hans-Jürgen M.
    Biol Chem; 2002 Sep 21; 383(7-8):1139-41. PubMed ID: 12437098
    [Abstract] [Full Text] [Related]

  • 18. LEKTI-1 in sickness and in health.
    Roelandt T, Thys B, Heughebaert C, De Vroede A, De Paepe K, Roseeuw D, Rombaut B, Hachem JP.
    Int J Cosmet Sci; 2009 Aug 21; 31(4):247-54. PubMed ID: 19467033
    [Abstract] [Full Text] [Related]

  • 19. The 420K LEKTI variant alters LEKTI proteolytic activation and results in protease deregulation: implications for atopic dermatitis.
    Fortugno P, Furio L, Teson M, Berretti M, El Hachem M, Zambruno G, Hovnanian A, D'Alessio M.
    Hum Mol Genet; 2012 Oct 01; 21(19):4187-200. PubMed ID: 22730493
    [Abstract] [Full Text] [Related]

  • 20. Proteolytic processing of human growth hormone by multiple tissue kallikreins and regulation by the serine protease inhibitor Kazal-Type5 (SPINK5) protein.
    Komatsu N, Saijoh K, Otsuki N, Kishi T, Micheal IP, Obiezu CV, Borgono CA, Takehara K, Jayakumar A, Wu HK, Clayman GL, Diamandis EP.
    Clin Chim Acta; 2007 Feb 01; 377(1-2):228-36. PubMed ID: 17140555
    [Abstract] [Full Text] [Related]

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